Centre for Bioengineering
People
On this page:
- Academic Members
- Postdoc Research Assistants
- Professional Services
- Current PhD Projects
- Past PhD Projects
Academic Members
Prof Teresa Alonso-Rasgado |
Prof James Busfield |
Dr Christopher Chapman |
Dr Tina Chowdhury |
Dr Thilina Dulantha Lalitharatne |
Dr Ildar Farkhatdinov |
Prof Julien Gautrot |
Prof Himadri Gupta |
Dr Mohammad Hassannezhad |
Prof Karin Hing |
Prof Henri Huijberts |
Prof Thomas Iskratsch |
Prof Martin Knight |
Prof Rob Krams |
Prof Steffi Krause |
Prof David Lee |
Dr Marco Pensalfini |
Dr Caroline Roney |
Prof Hazel Screen |
Prof Julia Shelton |
Dr Lei Su |
Prof Gleb SukhorukovProfessor of Biomedical Materials |
Prof Elizabeth Tanner |
Prof Zion Tse |
Dr Stefaan Verbruggen |
Prof Wen Wang |
Postdoc Research Associates
Dr Laura BevisPostdoctoral Research Associate: Cardiovascular Digital Twins |
Dr Mahmoud Ehnesh |
Mr Thomas GriggsPostdoctoral Reserach Assisatnt in Elastomer Recycling |
Dr Timothy Hopkins |
Dr Hassan Kanso |
Dr Valeriia Kudriavtceva |
Mr William Amoako Kyei-ManuResearch Assistant |
Dr Roberto Leonardo Diaz |
Dr Jiajun LuoPDRA |
Dr Subrata MondalPostdoctoral Research Assistant in Biomechanics |
Dr Clémence Nadal |
Dr Sara Naderizadeh |
Dr Elis NewhamPostdoctoral Research Assistant |
Dr Dhruv Saxena |
Dr David Shepherd |
Dr Pamela SwiatlowskaPostdoctoral Research Assistant |
Dr Danae Zamboulis |
Dr Alexander Zolotarev |
Professional Services
Current PhD Projects
Thesis Title | Supervisor |
---|---|
Study of Liquid-liquid interfaces | Julien Gautrot |
A Machine Learning Model to Predict Preterm Birth | Tina Chowdhury |
INVESTIGATION OF THE CEMENT MANTLE STRESS IN THE ACETABULAR COMPONENT AFTER TOTAL HIP ARTHROPLASTY (THA) Hip replacement surgery is a common orthopaedic operation undertaken in order to repair a broken hip or to relieve pain due to osteoarthritis. In the UK alone, a total of 890,681 THA were performed between 2003 and 2016. In total hip arthroplasty surgery the acetabulum is prepared and a cup shaped shell and liner put in place of the worn cartilage and bone. The prosthetic joint is completed by a metal stem with a hip ball attached to the neck being inserted into the femur. A variety of designs and materials are now used for the components of the prosthesis. In terms of the acetabular component, the choice is between a cementless implant (metal shells) and a cemented implant (polyethylene shell). Hip replacements do however, have a finite life and wear out and fail in which case revision hip surgery is required. Liner wear and aseptic loosening are two acetabulum related components that can lead to failure of the implant. This project is in partnership with an orthopaedic consultant form Wrightington, Wigan and Leigh NHS Foundation Trust. | Teresa Alonso-Rasgado |
3D in vitro models; biofabrication; 3D bioprinting; | Thomas Iskratsch |
Nanoscale damage markers for early osteoarthritis detection in the bone-cartilage unit | Himadri Gupta |
Self-assembled peptide droplet interfaces for simple screening of stem cell microenvironments and micromanipulation of colonies | Julien Gautrot |
Prostate Cancer Detection | Zion Tse |
organ chip model development- - integrating mechanobiology | Hazel Screen |
Exploring tendon health and disease with tendon-on-a-chip models | Hazel Screen |
Engineering retinal vascularization on a chip to model pathological events in eye diseases and study the effect of modulator drugs | Julien Gautrot |
Robotic interface to simulate locomotion in VR | Ildar Farkhatdinov |
one-year Joint-Supervision Ph.D. student position | Himadri Gupta |
Investigating ventricular arrhythmia disease progression through UK Biobank data digital twins. | Caroline Roney |
SEMS-PHD-521 | Thomas Iskratsch |
Effect of mechanical stimulation on cell and collagen mechanics in human preterm amniotic membrane defects | Tina Chowdhury |
Development of a Polycystic Kidney Disease organ-chip model to study therapeutic regulation of primary cilia mechanobiology | Martin Knight |
High throughput analysis of mechanosensitive microRNA | Rob Krams |
Effect of ultrasound-controlled release by MCA's DD Systems | Gleb Sukhorukov |
Lifetime predictions of Elastomers | James Busfield |
Cell imaging with PEI-SICM - CSC studentship | Steffi Krause |
Development of an Organ-chip Model to examine Muscle Degeneration | Hazel Screen |
Determination of the optimum construct for lunate prosthetic | Teresa Alonso-Rasgado |
Nanoscale biophysics of cutaneous fibrosis | Himadri Gupta |
Long-term Tracking and Targeted Therapy of Mesenchymal Stem Cell Labeled Nanoparticles | Martin Knight |
Novel Models of Tendinopathy on a Chip | Hazel Screen |
Investigation of bone coverage for patients with hip dysplasia during uncemented total hip arthroplasty | Teresa Alonso-Rasgado |
Light Activated Antibacterial Membranes for Hernia Repair | Elizabeth Tanner |
Modelling and characterisation of cells in flows | Yi Sui |
Ion channel blockers effect on viability, cell migration and | Lei Su |
Microdroplet-based microfluidics for direct reprogramming of human pluripotent stem cells | Julien Gautrot |
Single-shot optical imaging system for hidden objects behind scattering media by Particle Swarm Optimization and Deep Learning | Lei Su |
Development of an arterial organ-chip to study the role of primary cilia in atherosclerosis | Martin Knight |
Needle-based diagnostic and therapeutic technologies for oncological applications | Zion Tse |
CSC/Visiting student | Julien Gautrot |
Development of a new High Throughput CRISPR platform for detection of microRNA | Rob Krams |
Towards in-situ optical and electrochemical imaging to monitor action potentials for in-vitro and in-vivo applications | Steffi Krause |
A Cohort of Virtual Human Atria with Personalised Electrophysiology for In-silico Prediction of Ablation and Pharmacology Therapy Outcome | Caroline Roney |
Developing a CRISPR Methodology for subtle modification of proteins in mammalian cells | Rob Krams |
Medical engineering, Healthcare Robotics, Wearable Smart Devices | Zion Tse |
AI-driven surgical inventory management to prevent waste in healthcare | Zion Tse |
Investigating the influence of synovium on cartilage response to inflammatory stimuli using predictive invitro models. | Martin Knight |
Elucidation of Smear Wear Mechanism | James Busfield |
miRNAS Sequence Embedding For Pathway Detection And Selectivity | Rob Krams |
The Role of Proteoglycans in Vascular Smooth Muscle Mechanosensing | Thomas Iskratsch |
DEVELOPMENT OF A NOVEL FAMILY OF BIOACTIVE BIORESORBABLE POLYLACTIC ACID ? SILICATE SUBSTITUTED HYDROXYAPATITE COMPOSITES FOR MUSCULOSKELETAL APPLICATIONS | Karin Hing |
Engineered Recombinant Strategies to Organo-Hydrogel Design with Applications from Plant-Based Foods to Tissue Engineering | Julien Gautrot |
Prototyping cost-effective medical robots | Zion Tse |
Numerical Modelling of Cancer cells in flows | Yi Sui |
Investigation of mechanobiological sensing in cell spreading with label-free photoelectrochemical imaging | Steffi Krause |
The combination of fluorescent AuNCs and microcapsules | Gleb Sukhorukov |
Flexible ultrasound sensor | Lei Su |
MRI Conditional Actuations and Prostate Intervention Systems | Zion Tse |
Magnetically Actuated Robots for Medical Interventions | Zion Tse |
Investigating the Effects of Catheter Electrode Arrangement | Caroline Roney |
A GraphNN model for rapid convergence of Navier Stokes Equations in blood flow | Rob Krams |
Design of synthetic nanostructured hydrogel to regulate microvascularisation | Julien Gautrot |
Digital Public Health | Zion Tse |
Investigating atrial fibrillation disease progression through UK Biobank data digital twins | Caroline Roney |
Sustainable Future Footwear and Fashion Technology | James Busfield |
Smart electronic skin with multi-sensing uints integration | Lei Su |
Design of polymer brush vectors for controlled RNA delivery. | Julien Gautrot |
Magnetic Soft Robots for interventional application | Zion Tse |
IL-10 signalling in human vascular development (human vascular cell differentiation from induced-pluripotent stem cell (iPSC)) | Wen Wang |
Filler Reinforcement of Elastomers | James Busfield |
Nanotechnology approaches for the investigation of cardiac mechanosensing | Thomas Iskratsch |
Optimisation of a Novel Polymeric Heart Valve | James Busfield |
Control of the Circadian Clock in Chondrocytes | David Lee |
The interfascicular matrix niche ? novel approaches to identify the aetiology of tendinopathy | Hazel Screen |
Optimisation of Tyre Wear Performance | James Busfield |
Perceptible gaps in audiological services within the NHS | Mohammad Hassannezhad |
A Dynamic Model of Soft Tissue Integration to Dental Hard Tissue | Thomas Iskratsch |
3D enhanced bioreactor for enhanced bone grafting | Karin Hing |
Using graphNN to predict new small molecules | Rob Krams |
Nanostructured Reinforcing Fillers to Enhance Physical and Mechanical Properties | James Busfield |
A PORTABLE GAIT EVENT DETECTION SYSTEM FOR PATIENTS WITH FOOT DROP | Teresa Alonso-Rasgado |
Graphene based transparent electrodes for tuneable optical devices | James Busfield |
Hydrogel Waveguides for Clinical Applications | Lei Su |
SEMS-PHD-520 | Thomas Iskratsch |
Innovative Tactile and Optical Sensing and Actuating Devices | James Busfield |
Hybrid Perovskite Nanocrystals: Synthesis, Stability and Defect Tolerance | Lei Su |
Polymer brushes as a delivery tool to DNA vaccine | Julien Gautrot |
Inertial Measurement Unit based Miniaturised Devices for Physiological Monitoring using Vibrational Signals | Zion Tse |
AI tool to predict protein phosphorylations that are dangerous for cancerous tumors | Rob Krams |
Designing Mechanism-Specific Treatment Approaches for Atrial Fibrillation Through Computational Modelling | Caroline Roney |
Role of CD34+ Stem Cells in Isografted Vessel Remodelling | Wen Wang |
Single crystal perovskite optical and electronic devices | Lei Su |
Single optical fibre imaging | Lei Su |
Cardiomyocytes, Mechanobiology, Rigidity sensing, Micropatterning, Traction Force Measurement | Thomas Iskratsch |
Nano-Microstructured Synthetic Cell Instructive Hydrogels for Organ-on-Chip Engineering | Julien Gautrot |
3D photoelectrochemical imaging | Steffi Krause |
Development of organ-chip models of the growth plate with mechanical stimulation | Martin Knight |
Past PhD Projects
Thesis Title | Supervisor | Year |
---|---|---|
Electrospinning high toughness biomimetic polystyrene nanocomposites | Asa Barber, Himadri Gupta | 2017 |
The Effects of Loading Frequency on Tenocyte Matabolism | Hazel Screen | 2017 |
Wear and corrosion testing of modular hip prostheses | Julia Shelton | 2017 |
Motion of deformable capsules in complex flows | Yi Sui | 2017 |
Composite inorganic particles/polyelectrolyte microcapsules: fabrication and application | Gleb Sukhorukov | 2017 |
SmartNanoHeat - Self-regulating heating compounds | Emiliano Bilotti, James Busfield | 2017 |
Fabrication of non(low) permeable microcapsules and further study | Gleb Sukhorukov, Himadri Gupta | 2017 |
Predicting tyre compound wear. | James Busfield, Emiliano Bilotti | 2017 |
Micro-patterning of peptide-based biomaterials | Julien Gautrot, Hazel Screen | 2017 |
Development of materials and applications for electroactive composites | James Busfield, Federico Carpi | 2017 |
Fatigue life prediction in aircraft tyres | James Busfield | 2017 |
Electric Breakdown of Dielectric Elastomer Actuator Materials | Federico Carpi, James Busfield | 2017 |
Naturally Inspired Multi-layer Composite Films on Planar and Modulated Surfaces | Gleb Sukhorukov, Ton Peijs | 2016 |
To Fabricate and Study the Properties of the Intelligent Microencapsulated Liquid Particles Containing Biologically Active Compounds | Gleb Sukhorukov | 2016 |
Micro-structure reorganisation of the aortic heart valve under a biaxial loading condition | Hazel Screen, Wen Wang | 2016 |
The effects of the rate of hypo-osmotic challenge and IFT88 mutation on the biomechanics of chondrocytes. | Martin Knight, Wen Wang | 2016 |
Roles of primary cilia in hMSC in differentiation | Martin Knight | 2016 |
Biomimetic Layered Nanocomposites with Tunable Dynamical Mechanical Properties: Synthesis, Imaging and Characterisation | Himadri Gupta, Nicola Pugno | 2016 |
A novel fibre composite system to investigate tenocyte metabolism under physiological and pathological loading conditions. | Hazel Screen | 2016 |
Development of a 3D Perfusion System to Monitor Response of Osteoblast-like Cells Incubated on Synthetic Bone Graft Substitute Granules with Varied Hierarchical Porosities under Dynamic Conditions | Karin Hing | 2016 |
Developing Cationic Nanoparticles for Gene Delivery | Julien Gautrot, John Stark | 2016 |
Bone Quality Changes at the Nanoscale in Metabolic Bone Diseases assessed by Synchrotron X-ray Imaging | Himadri Gupta | 2016 |
The synergistic role of mechanical stimuli and VEGF treatment in stem cell differentiation to endothelial cells | Wen Wang | 2016 |
The Strain Dependent Dielectric Behaviour of Carbon Black Filled Natural Rubber | James Busfield, Emiliano Bilotti | 2016 |
Interaction between the circulating blood and vascular endothelial cells in health & disease. Cell Mechanics for endothelial glycocalyx | Wen Wang, Asa Barber | 2016 |
The role of HDAC7-related peptide in stem cell differentiation towards endothelial cell | Wen Wang | 2016 |
Investigating the effects of cholesterol on phospholipid bilayer with molecular dynamics simulations. | Wen Wang, Yiling Lu | 2016 |
Functional impact of microRNA-34a on stem cell differentiation towards smooth muscle cell | Wen Wang | 2015 |
Mechanical properties of stem cells using micropipette aspiration | Martin Knight, David Lee | 2015 |
The Role of DKK3 in Vascular Smooth Muscle Differentiation | Wen Wang | 2015 |
Electrical stimulation on cell-cell interactions in vitro | Wen Wang | 2015 |
Microcapsule for targetted drug delivery to diseased tissues | Wen Wang, Gleb Sukhorukov | 2015 |
Complex mechanical conditioning of cell-seeded constructs can influence chondrocyte activity | Julia Shelton, Dan Bader | 2015 |
Microfluidics for a novel bioreactor | Wen Wang, Pankaj Vadgama | 2015 |
Combined Impedance and Fluorescence Imaging of Polymeric Microcapsules using Photocurrent Measurements at silicon/SAM/electrolyte Field Effect Structures | Steffi Krause | 2015 |
Monitoring of Bone Quality and Penetration in Osteoinductive Scaffolds with Varied Strut Porosity | Karin Hing | 2015 |
Enhancing Osteogenesis in Porous Bone Graft Substitutes Through Control of Microporosity | Karin Hing | 2015 |
The development of a novel nanostructured silica filler for high friction and low rolling resistance rubber applications. | James Busfield | 2015 |
Modelling and Interactional Control of a Multi-fingered Robotic Hand for Grasping and Manipulation | M Hasan Shaheed, Henri Huijberts | 2015 |
Investigation of Protein Mediated Control of Oteoinductivity in Porous Bone Graft Substitutes using Fluorescent Probes | Karin Hing, Alice Sullivan | 2015 |
The behaviour of hollow sphere filled rubber materials under strain | James Busfield | 2014 |
Microcapsule internalization be cells in vitro caused by physical and biochemical stimuli | Gleb Sukhorukov, Wen Wang | 2014 |
Failure of Rubber Components under Fatigue | James Busfield | 2014 |
Accelerated wear protocols for understanding clinical wear in modern hip prostheses | Julia Shelton, Martin Knight | 2014 |
Novel polymeric matrix and its interaction withbiological cells | Wen Wang, Ton Peijs | 2014 |
Analysis of Alterations in Matrix Quality at Nanoscale in Metabolic Bone Diseases using Synchrotron X-ray Diffraction | Himadri Gupta | 2013 |
Interaction between primary cilia length and hedgehog signalling in response to mechanical and thermal stress | Martin Knight | 2013 |
Tearing of rubber | James Busfield | 2013 |
Nuclear Related Responses to Osmotic Challenge in Chondrocytes | David Lee, Martin Knight | 2013 |
A Biomechanical Characterisation of Eccentric and Concentric Loading of the Triceps Surae Complex | Hazel Screen | 2013 |
UV-Triggered Encapsulation and Release by Multilayer Microcapsules | Gleb Sukhorukov | 2013 |
The Nanostructure of Impant-Induced Fibrosis (MPhil) | Himadri Gupta | 2013 |
Investigation into the use of carbon nanotubes networks as gate electrodes in field-effect gas sensors with increased functionality | Steffi Krause | 2013 |
Formation control of nonholonomic mobile robots: the virtual structure approach | Henri Huijberts | 2012 |
Laser scanning system for microscopic and macroscopic investigations of chemical semiconductor sensors | Steffi Krause | 2012 |
The Impact and Deformation of Press-Fit Metal Acetablular Components | Julia Shelton, James Busfield | 2012 |
Multilayer Microcapsules for Delivery, Control and Triggered Release of Bioactive Compounds | Gleb Sukhorukov | 2012 |
Natural Rubber/Organoclay Nanocomposites | James Busfield | 2012 |
Spatial distribution, temporal development and mechanical properties of the endothelial glycocalyx in vitro | Wen Wang | 2012 |
Modelling studies on biological tissue property and mechanical responses under external stimuli | Wen Wang | 2012 |
Viscoelastic Response of Cells and the Role of Actin Cytoskeletal Remodelling | Martin Knight | 2012 |
Novel Fluorescent probes for Analysis of Protein interactions under truly physiological conditions with real Medical devices | Karin Hing | 2012 |
Structure-Function Relationships in the Aortic Valve | Hazel Screen | 2012 |
Influence of coatings on ion release from large diameter metal-on-metal hip bearings | Julia Shelton | 2012 |
Computational modelling of flows in porous scaffold materials using a lattice Boltzmann method | Wen Wang | 2011 |
Can Interface Conditions be Modified by Support Surfaces to Minimise the Risk of Pressure Ulcer Development? | Wen Wang, Dan Bader | 2011 |
microRNAs play a role in human embryonic stem cell differentiation into endothelial cells | Wen Wang | 2011 |
Processing of Polymer-based Systems for Improved Performance and Controlled Release | Gleb Sukhorukov, Ton Peijs | 2011 |
Development of a non-invasive method to detect pericellular spatial oxygen gradients using FLIM | Martin Knight | 2011 |
The influence of test parameters and surface modifications on the wear of total hip replacements | Julia Shelton | 2011 |
The Influence of Microstructure on the Mechanical Behaviours of Tendons | Hazel Screen, Julia Shelton | 2010 |
Characterisaction of Human Mesenchymal Stem Cell Metabolism during Proliferation and Differentiation | David Lee, Joost deBruijn | 2010 |
Transmission power control in wireless networks | Henri Huijberts | 2010 |
Viscoelastic Properties of Elastomer under Complex Loading | James Busfield | 2010 |
Investigation and Modelling of Rubber Friction | James Busfield | 2010 |
Novel biosensors and Their application in Mass Transport | Wen Wang, Pankaj Vadgama | 2009 |
Carbon Black Filler Reinforcement of Elastomers | James Busfield | 2009 |
Investigation into the Sensitivity and Resolution of Scanning Photo-Induced Impedance Microscopy | Steffi Krause | 2009 |
Optically addressable, integrative composite polymer microcapsules | Gleb Sukhorukov | 2009 |
The potential of pulsed low-intensity ultrasound to stimulate chondrocytes in a 3D model system | Martin Knight | 2009 |
The influence of direct current electrical stimulation on chondrocytes in a 3D model system | Dan Bader, David Lee | 2008 |
Temporal regulation of tenocyte metabolism in strained fascicles | David Lee, Julia Shelton | 2008 |
In vitro wear of metal-on-metal hip replacements: a multifactorial problem. | Julia Shelton | 2008 |
Mechanisms of the improvced Biological Response with Silicate Substitution in Hydroxy Apatite. | Karin Hing | 2008 |