Centre for Bioengineering

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• Centre Associates

Academic Members

Prof Teresa Alonso-Rasgado PhD Professor in Mechanical Engineering  +44 (0)20 7882 3028      t.alonso@qmul.ac.uk

Prof James Busfield FREng, MA, PhD, CEng, FIMMM, FHEA Professor of Materials Examining the physical behaviour by experiment and modelling techniques of polymers and soft matter such as elastomers and rubber materials. Properties of interest include abrasion, friction, fracture, creep, fatigue, viscoelastic behaviour, modulus enhancement, self healing, recycling, ageing and composite filler reinforcement. Developing smart soft materials that can sense their environment and soft actuating materials that can change shape in response to a physical stimulus.  j.busfield@qmul.ac.uk

Dr Christopher Chapman PhD, CEng, CSci, MIMMM, MIPEM Lecturer in Bioengineering Bioelectronics design and fabrication for central nervous system and peripheral nervous system targets. Experience using both metals and conducting polymers to create soft and flexible bioelectronic implants via laser-based and traditional microfabrication.  christopher.chapman@qmul.ac.uk

Dr Tina Chowdhury BSc, MSc, PhD, PGCAP, SFHEA Reader in Regenerative Medicine Regenerative medicine  +44 (0)20 7882 7560      t.t.chowdhury@qmul.ac.uk

Dr Thilina Dulantha Lalitharatne PhD, MSc, BSc(Hons) Eng Lecturer in Robotics and Mechatronics Human-Robot Interaction (HRI), Social Robotics, Medical Robotics, Brain-Machine Interface (BMI/BCI), Soft Robotics, Bio-inspired Robotics  t.lalitharatne@qmul.ac.uk

Prof Julien Gautrot FRSC, PhD Professor of Biomaterials and Biointerfaces Synthesis and characterisation of biomaterials. Micro- and nano-patterning. Bio-interfaces. Stem cell biology.  +44 (0)20 7882 5263      j.gautrot@qmul.ac.uk

Prof Himadri Gupta PhD, MSc, FHEA Professor of Bioengineering and Biophysics Structure-function in tissue mechanics; Ageing, degeneration and fibrotic disorders in ECM; Developing multiscale and correlative imaging; small-angle X-ray scattering and modelling  +44 (0)20 7882 8867      h.gupta@qmul.ac.uk

Prof Karin Hing PhD, BSc, CEng, MIMMM, FHEA, FRSA, FWES Professor of Biomaterials and Tissue Regeneration My research is focused around the development of pioneering biomaterials and healthcare therapies through development of novel materials and processing technologies and investigation of the phenomena behind biocompatibility, and the stimulation of tissue regeneration. I am particularly interested in understanding the mechanisms behind enhanced bone healing or regeneration in the presence of porous synthetic scaffolds, known as synthetic bone graft substitutes, via manipulation of both synthetic graft chemistry and hierarchical pore structure. This has resulted in the development of 3D mechanosensitive in vitro models for investigation of these phenomena in the laboratory. I also have extensive experience in translating research from the bench to the bed side through my involvement in the successful development and commercialisation of a progressive series of synthetic bone graft substitute materials with tuneable hierarchical structures to support rapid, reliable bone regeneration, which are now in global clinical use in a range of applications including trauma, maxillofacial reconstruction, joint revision and spine surgery.  +44 (0)20 7882 7804      k.a.hing@qmul.ac.uk

Prof Henri Huijberts MSc PhD(Twente, Netherlands) PFHEA CMath FIMA Professor of Engineering Science and Education Nonlinear control systems, nonlinear dynamics, chaos, synchronisation, robotics, engineering and mathematics education, educational leadership, digital education  +44 (0)20 78869      h.j.c.huijberts@qmul.ac.uk

Prof Thomas Iskratsch Dipl.-Ing., PhD, FHEA Professor of Cardiovascular Mechanobiology and Bioengineering Cardiomyocyte and Vacular Smooth Muscle Cell Mechanobiology, Rigidity Sensing, Micro and Nanopatterning, Cellular Force Measurement  +44 (0)20 7882 3674      t.iskratsch@qmul.ac.uk

Prof Martin Knight BEng, MSc, PhD, FHEA Professor of Mechanobiology As a bioengineer, my research is focussed on the development of organ-on-a-chip technology and other complex in vitro models. These in vitro models can transform pre-clinical testing of new drugs and therapeutics, acelerating the delivery of safer, more effective medicines. The models are also helping us to better understand human health and disease. As a professor of 'mechanobiology' I am interested in how living cells and tissues respond to biomechanical forces and how this should be incorporated into organ-chip design. Related to this, my research team examine the role of the cellular structures known as primary cilia. We are investigating structure-function relationships in this poorly understood organelle and whether manipulation of cilia can be used as a therapeutic strategy. I work on a variety of different diseases including osteoarthritis, cancer, atherosclerosis and inflammation and associated tissues/organs such as cartilage, synovium, bone, kidney and artery.  +44 (0)20 7882 8868      m.m.knight@qmul.ac.uk

Prof Rob Krams MD, PhD Professor of Molecular Bioengineering mechanotransduction, flow studies, molecular biology, CRISPR, knock out, knock in, finite element modelling, fluid structure modelling, imaging, animal studies  +44 (0)20 7882 7940      r.krams@qmul.ac.uk

Prof Steffi Krause Dr. rer. nat., MRSC, FHEA Professor of Electroanalytical Systems My research focuses on the development of electrochemical imaging and chemical and biological sensor technologies, and my group has recently developed photoelectrochemical imaging with high spatiotemporal resolution. This measurement technology has shown great potential in the functional imaging of living cells and is expected to aid the understanding of disease mechanisms and biological processes. If you want to find out more, please follow the link to my inaugural lecture above.  +44 (0)20 7882 3747      s.krause@qmul.ac.uk

Prof David Lee BSc (Hons), MA, PhD Deputy Vice Principal - Impact (Enterprise and Commercial Innovation) Tissue engineering and mechanobiology, Mesenchymal stem cell biology  +44 (0)20 7882 8874      d.a.lee@qmul.ac.uk

Dr Marco Pensalfini BSc (Bologna); MSc (Bologna); PhD (Dr. Sc. ETH) Lecturer in Mechanical and Biomedical Engineering My expertise is at the interface of mechanical and biomedical engineering, with a focus on the multiscale mechanics of soft fibrous biomaterials. A central theme is the development of novel experimental approaches combining mechanics and imaging techniques to unravel mechanisms of load redistribution across tissue lengthscales and address their mechanobiological relevance. I also have broad experience in establishing two-way links between experiments and corresponding computational models with predictive or interpretative function, including inverse FEA and hierarchical Bayesian inverse analysis. My work is intrinsically multidisciplinary, and over the years I have initiated multiple collaborations with clinical and industrial partners.  m.pensalfini@qmul.ac.uk

Prof Nicola Pugno MSc PhD Professor of Materials Science Bio-inspired, Bionic, Nano, Meta Materials and Mechanics (including Fracture Mechanics, Solid Mechanics, Structural Mechanics, Tribology, Wettability, Adhesion, Scaling laws, etc.)  +44 (0)20 7882 6310      n.pugno@qmul.ac.uk

Dr Caroline Roney MMath, MRes, PhD Reader in Computational Medicine My research interests are in developing engineering methodologies to personalise treatment approaches for cardiac arrhythmias. We use a combination of signal processing, image processing, machine learning and computational modelling techniques to develop novel techniques for investigating cardiac arrhythmia mechanisms from clinical imaging data and electrical recordings. The ultimate aim of our research is to translate these tools to predict optimal patient-specific treatment strategies in the clinic. We work closely with clinical, basic science and industrial collaborators.  c.roney@qmul.ac.uk

Dr S.M.Hadi Sadati PhD Lecturer in Robotics and Mechatronics  s.sadati@qmul.ac.uk

Prof Hazel Screen BEng MRes PhD(Lond) CEng, FIMechE, MIPEM Professor of Biomedical Engineering My research aims to understand how our tissues are built to be able to withstand the loads they experience in the body. I am particularly interested in understanding tendon and heart valve; how and why they get injured, and ways to prevent this happening. By looking at the ways a tissue is supposed to work when it is healthy, we can identify how small changes in the structure, such as those which occur with age, can make injury more likely and look to prevent or treat these specifically.  h.r.c.screen@qmul.ac.uk

Prof Julia Shelton BA(Cantab) PhD(Lond) Professor of Biomechanical Engineering Wear of total hip replacements, surface coatings, particle analysis, orthopaedic systems, tissue engineering, tendon mechanics, modelling of taper mechanics  +44 (0)20 7882 8877      j.shelton@qmul.ac.uk

Dr Karen Shoop BA MSc PhD Senior Lecturer in Design  +44 (0)20 7882 8014      karen.shoop@qmul.ac.uk

Prof Lei Su BSc, MRes, PhD, FHEA Professor of Photonics My research is centred on sensors and instrumentation, optical devices, optoelectronic materials, wearable ultrasound for imaging, detection, monitoring and communication, interfacing with Artificial Intelligence, Materials, Chemistry and Nanotechnology, in applications such as healthcare, energy and security.  +44 (0)20 7882 5184      l.su@qmul.ac.uk

Prof Yi Sui PhD, MInstP, Fellow HEA Professor of Fluid Mechanics  +44 (0)20 7882 7763      y.sui@qmul.ac.uk

Prof Elizabeth Tanner OBE, FREng, FRSE, PhD (Hon Caus), MA, DPhil, FIMMM, FIMechE, FIPEM, CEng, CSci Bonfield Professor of Biomedical Materials My research interests are in the development, testing and use of biomaterials for bone and joint replacement. In particular composites of bioactive ceramics and polymers which can encourage bone ongrowth yet have sufficient mechanical properties to be used for load bearing applications. These are based on either non-degradable or degradable artificial or natural polymers depending on application. In parallel I have interests in the mechanical properties of bone and the effects of pathology on these properties.  +44 (0)20 7882 6785      k.e.tanner@qmul.ac.uk

Prof Zion Tse PhD, CEng, FIET, FIMechE, SMIEEE Director, Centre for Bioengineering Intelligent Robotics, AI & Digital Technologies, Imaging & Medical Assistive Devices, and AI Healthcare  z.tse@qmul.ac.uk

Dr Stefaan Verbruggen BEng, PhD, FHEA Lecturer in Medical Technology Bone biomechanics and mechanobiology, Developmental biomechanics, cancer mechanobiology  s.verbruggen@qmul.ac.uk

Prof Wen Wang PhD, CEng, FIMechE, FHEA, FAIMBE, FREng Vice-Principal and Executive Dean for Science and Engineering Vascular endothelial mechanics, cell mechanobiology, flow and solute transport in extracellular matrices, microcirculation, arterial haemodynamics, cell & tissue mechanics  +44 (0)20 7882 3031      wen.wang@qmul.ac.uk

Centre Associates