Centre for Bioengineering

People

On this page:

• Academic Members
• Postdoc Research Assistants
• Professional Services
• Current PhD Projects
• Past PhD Projects

Academic Members

Prof Teresa Alonso-Rasgado PhD Professor in Mechanical Engineering  +44 (0)20 7882 3028      t.alonso@qmul.ac.uk

Prof James Busfield FREng, MA, PhD, CEng, FIMMM, FHEA Professor of Materials Examining the physical behaviour by experiment and modelling techniques of soft matter such as elastomers and rubber materials. Properties of interest include abrasion, friction, fracture, creep, fatigue, viscoelastic behaviour, modulus enhancement, self healing, recycling, ageing and composite filler reinforcement. Developing smart soft materials that can sense their environment and soft actuating materials that can change shape in response to a physical stimulus.  +44 (0)20 7882 8866      j.busfield@qmul.ac.uk

Dr Christopher Chapman PhD Lecturer in Bioengineering Bioelectronics design and fabrication for central nervous system and peripheral nervous system targets. Experience using both metals and conducting polymers to create soft and flexible bioelectronic implants via laser-based and traditional microfabrication.  christopher.chapman@qmul.ac.uk

Dr Tina Chowdhury BSc, MSc, PhD, PGCAP, SFHEA Senior Lecturer in Regenerative Medicine Inflammation, mechanobiology, regenerative medicine, ageing.  +44 (0)20 7882 7560      t.t.chowdhury@qmul.ac.uk

Dr Claudia Contini PhD Lecturer in Biochemical Engineering Dr Contini's research interests lie in the field of bottom-up synthetic biology with a focus on the design of synthetic life-like systems that mimic biological properties and functions for biotechnological and biomedical applications.  +44 7552 130605      c.contini@qmul.ac.uk

Dr Thilina Dulantha Lalitharatne PhD, MSc, BSc(Hons) Eng Lecturer in Robotics and Mechatronics Human-Robot Interaction (HRI), Social Robotics, Medical Robotics, Brain-Machine Interface (BMI/BCI), Soft Robotics, Bio-inspired Robotics  t.lalitharatne@qmul.ac.uk

Dr Ildar Farkhatdinov PhD Senior Lecturer in Robotics Assistive/medical robotics, human-robot interaction, haptics, virtual reality, control theory.  i.farkhatdinov@qmul.ac.uk

Prof Julien Gautrot PhD Professor in Biomaterials and Biointerfaces Synthesis and characterisation of biomaterials. Micro- and nano-patterning. Bio-interfaces. Stem cell biology.  +44 (0)20 7882 5263      j.gautrot@qmul.ac.uk

Prof Himadri Gupta PhD, MSc, FHEA Professor of Bioengineering and Biophysics Multiscale imaging of hierarchical materials; Synchrotron X-ray biophysics; In situ and scanning X-ray scattering techniques; Nano- and microscale tissue mechanics; Ageing and degeneration of musculoskeletal tissues; Mechanobiology  +44 (0)20 7882 8867      h.gupta@qmul.ac.uk

Dr Mohammad Hassannezhad PhD, MINCOSE Lecturer in Systems Engineering Model-Based Systems Engineering, Socio-Technical Systems Design, System Architecture, System of Systems, Human-Machine Interactions, Resilience Engineering  m.hassannezhad@qmul.ac.uk

Dr Hossein Heidari BSc, MSc, PhD Lecturer in Biomedical Engineering Designing light-based additive biofabrication processes Developing functional human tissue and organ models Discovering advanced photo-active biomaterials and inks  h.heidari@qmul.ac.uk

Dr Karin Hing CEng, PhD, BSc, MIMMM, FRMS, FWES, FHEA Reader in Biomedical Materials My research is focused around the development of pioneering biomaterials and healthcare therapies through development of novel materials and processing technologies and investigation of the phenomena behind biocompatibility, and the stimulation of tissue regeneration. I am particularly interested in understanding the mechanisms behind enhanced bone healing or regeneration in the presence of porous synthetic scaffolds, known as synthetic bone graft substitutes, via manipulation of both synthetic graft chemistry and hierarchical pore structure. This has resulted in the development of 3D mechanosensitive in vitro models for investigation of these phenomena in the laboratory. I also have extensive experience in translating research from the bench to the bed side through my involvement in the successful development and commercialisation of a progressive series of synthetic bone graft substitute materials with tuneable hierarchical structures to support rapid, reliable bone regeneration, which are now in global clinical use in a range of applications including trauma, maxillofacial reconstruction, joint revision and spine surgery.  +44 (0)20 7882 7804      k.a.hing@qmul.ac.uk

Dr Thomas Iskratsch Dipl.-Ing. (Equiv. to MSc/MEng), PhD Reader in Cardiovascular Mechanobiology and Bioengineering Cardiomyocyte and Vacular Smooth Muscle Cell Mechanobiology, Rigidity Sensing, Micro and Nanopatterning, Cellular Force Measurement  +44 (0)20 7882 3674      t.iskratsch@qmul.ac.uk

Prof Martin Knight BEng, MSc, PhD, FHEA Professor of Mechanobiology My research is focussed on 'mechanobiology' or how living cells and tissues respond to physical forces. I am interested in the role of the cellular structures known as primary cilia. My group are investigating whether manipulation of cilia can be used as a therapeutic strategy. My work also explores the development of organ-on-a-chip models incorporating biomechanical stimulation for understanding human biology in health and disease and predicting the response to therapeutics. I work on a variety of different tissues such as cartilage, synovium, bone, kidney and artery, as well as diseases including osteoarthritis, cancer, atherosclerosis and inflammation.  +44 (0)20 7882 8868      m.m.knight@qmul.ac.uk

Prof Rob Krams MD, PhD Professor of Molecular Bioengineering mechanotransduction, flow studies, molecular biology, CRISPR, knock out, knock in, finite element modelling, fluid structure modelling, imaging, animal studies  +44 (0)20 7882 7940      r.krams@qmul.ac.uk

Prof Steffi Krause Dr. rer. nat., MRSC, FHEA Professor of Electroanalytical Systems My research focuses on the development of electrochemical imaging and chemical and biological sensor technologies, and my group has recently developed photoelectrochemical imaging with high spatiotemporal resolution. This measurement technology has shown great potential in the functional imaging of living cells and is expected to aid the understanding of disease mechanisms and biological processes.  +44 (0)20 7882 3747      s.krause@qmul.ac.uk

Dr Ravinash Krishna Kumar MSci, PhD EPSRC Open Plus Fellow and Lecturer in Medical Technology Our group uses 3D printing and fluidic technologies to 1) build new microbiome models for understanding host-microbial community relationship, 2) build synthetic tissues for controlling living tissues, and 3) build new engineered living materials. Our group is highly interdisciplinary and spans 3D printing, method development, materials science, microbiology/cell biology, ecology, and modelling.  r.krishnakumar@qmul.ac.uk

Prof David Lee BSc (Hons), MA, PhD Deputy Vice Principal - Impact (Enterprise and Commercial Innovation) Tissue engineering and mechanobiology, Mesenchymal stem cell biology  +44 (0)20 7882 8874      d.a.lee@qmul.ac.uk

Dr Caroline Roney MMath, MRes, PhD Lecturer in Computational Medicine My research interests are in developing engineering methodologies to personalise treatment approaches for cardiac arrhythmias. We use a combination of signal processing, image processing, machine learning and computational modelling techniques to develop novel techniques for investigating cardiac arrhythmia mechanisms from clinical imaging data and electrical recordings. The ultimate aim of our research is to translate these tools to predict optimal patient-specific treatment strategies in the clinic. We work closely with clinical, basic science and industrial collaborators.  c.roney@qmul.ac.uk

Prof Hazel Screen BEng MRes PhD(Lond) CEng Professor of Biomedical Engineering My research aims to understand how our tissues are built to be able to withstand the loads they experience in the body. I am particularly interested in understanding tendon and heart valve; how and why they get injured, and ways to prevent this happening. By looking at the ways a tissue is supposed to work when it is healthy, we can identify how small changes in the structure, such as those which occur with age, can make injury more likely and look to prevent or treat these specifically.  +44 (0)20 7882 8875      h.r.c.screen@qmul.ac.uk

Prof Julia Shelton BA(Cantab) PhD(Lond) Professor of Biomechanical Engineering Wear of total hip replacements, surface coatings, particle analysis, orthopaedic systems, tissue engineering, tendon mechanics  +44 (0)20 7882 8877      j.shelton@qmul.ac.uk

Dr Lei Su BSc, MRes, PhD, FHEA Reader in Photonics My research is centred on sensors and instrumentation, optical devices and optoelectronic materials for imaging, detection, monitoring and communication, interfacing with Artificial Intelligence, Materials, Chemistry and Nanotechnology, in applications such as healthcare, energy and security.  +44 (0)20 7882 5184      l.su@qmul.ac.uk

Prof Yi Sui PhD, MInstP, Fellow HEA Professor of Fluid Mechanics  +44 (0)20 7882 7763      y.sui@qmul.ac.uk

Prof Gleb Sukhorukov Professor of Biomedical Materials Physical Chemistry, Biophysics, Materials Science. Area of research: Multifunctional Nanoengineered Delivery Systems  +44 (0)20 7882 5508      g.sukhorukov@qmul.ac.uk

Prof Elizabeth Tanner OBE, FREng, FRSE, PhD (Hon Caus), MA, DPhil, FIMMM, FIMechE, FIPEM, CEng, CSci Bonfield Professor of Biomedical Materials My research interests are in the development, testing and use of biomaterials for bone and joint replacement. In particular composites of bioactive ceramics and polymers which can encourage bone ongrowth yet have sufficient mechanical properties to be used for load bearing applications. These are based on either non-degradable or degradable artificial or natural polymers depending on application. In parallel I have interests in the mechanical properties of bone and the effects of pathology on these properties.  +44 (0)20 7882 6785      k.e.tanner@qmul.ac.uk

Prof Zion Tse PhD, CEng, FIET, FIMechE, SMIEEE Director, Centre for Bioengineering Digital Health, Smart Wearables, Mobile Health, Human-Computer Interaction, AI Medical Imaging, Computer-aided Diagnosis, Digital Mental Health & Medical Robotics  z.tse@qmul.ac.uk

Dr Stefaan Verbruggen BEng, PhD, FHEA Lecturer in Medical Technology Bone biomechanics and mechanobiology, Developmental biomechanics, cancer mechanobiology  s.verbruggen@qmul.ac.uk

Prof Wen Wang PhD, CEng, FIMechE, FHEA, FAIMBE, FREng Vice-Principal and Executive Dean for Science and Engineering Vascular endothelial mechanics, cell mechanobiology, flow and solute transport in extracellular matrices, microcirculation, arterial haemodynamics, cell & tissue mechanics  +44 (0)20 7882 3031      wen.wang@qmul.ac.uk

Postdoc Research Associates

Dr Georgios Boras Postdoctoral Research Assistant My PhD research involved the epitaxial growth of III-V semiconductor nanostructures such as nanowires and quantum dots along with their morphological, structural and optical characterization. It also included the study of the aforementioned structures for implementation in optoelectronic devices. My current research focuses on the synthesis of perovskite thin films with a high potential to be employed for device applications such as solar cells.  g.boras@qmul.ac.uk  Supervisor: Lei Su

Dr Minerva Bosch Fortea Postdoctoral Research Associate  m.bosch@qmul.ac.uk  Supervisor: Julien Gautrot

Dr Oliver Brookes Postdoctoral Research Assistant  oliver.brookes@qmul.ac.uk  Supervisor: David Lee

Dr Mahmoud Ehnesh BSc, MSc, PhD, AFHEA. Postdoctoral Research Associate Bio-medical Engineering, Electrical and Electronics Engineering. My research focus is on cardiac arrhythmias, especially Atrial Fibrillation, with a particular interest in digital signal processing and intelligent algorithms of biomedical signals.  +44(0)20 7882 8004      m.ehnesh@qmul.ac.uk  Supervisor: Caroline Roney

Dr Simon Grossemy Postdoctoral Research Assistant  s.grossemy@qmul.ac.uk  Supervisor: Hazel Screen

Dr Hannah Heywood PhD Postdoctoral Research Fellow Circadian biology in mechanosensitive cells: My current research investigates the interaction between physiological and pathological mechanical stimuli and the circadian clock in mechanosensitive cells, such as the cardiovascular system and musculoskeletal system. Bioenergetics and metabolism: I discovered the Crabtree metabolic phenotype in chondrocytes and studied the contribution of energy metabolism to chondrocyte phenotype. I devised my own techniques for characterizing the bioenergetic phenotype in living cells, which have been used to understand the metabolism of stem cells during differentiation, cartilage cells, cancer stem cells. Tissue Engineering and Regenerative Medicine: Focusing on tissue engineering and cell therapies for cartilage repair.  +44 (0)20 7882 5368      h.k.heywood@qmul.ac.uk  Supervisor: Martin Knight

Dr Timothy Hopkins PhD Versus Arthritis Research Fellow I am currently working on a Versus Arthritis funded Foundation Fellowship within SEMS. The aim of the fellowship is to develop an organ-on-a-chip model of human cartilage and synovium (â??joint-on-a-chipâ??) to understand how these tissues interact in the human knee in health and disease. We believe that this interaction plays a key role in the pathobiology of osteoarthritis and influences how individual patients respond to treatment. We are seeking to improve our understanding in these key areas and ultimately to use the joint-on-a-chip to stratify and personalise therapies for osteoarthritis.  tim.hopkins@qmul.ac.uk  Supervisor: Martin Knight

Dr Sheetal Inamdar MEng, PhD Postdoctoral Research Assistant My work is focused on understanding how the collagen network in cartilage contributes to the tissues mechanical properties both in health and disease. More specifically, I utilise small angle X-ray scattering techniques combined with in-situ mechanics to probe the complex nanoscale mechanisms within the tissue. This combined methodology provides real time information into how the collagen fibrils behave under tissue level loading.  s.r.inamdar@qmul.ac.uk  Supervisor: Himadri Gupta

Dr Anureet Kaur MRSC Research Assistant  anureet.kaur@qmul.ac.uk  Supervisor: James Busfield

Dr Valeriia Kudriavtceva BSc, MSc, PhD Postdoctoral Research Assistant  v.kudriavtceva@qmul.ac.uk  Supervisor: Gleb Sukhorukov

Dr Weiqi Li BMed, MMed, PhD Postdoctoral Research Assistant My research focuses on the vascular biology and vascular engineering. Particular interest goes to the endothelial glycocalyx, a protective layer along the luminal surface of the blood vessel. I aim to elucidate how the glycocalyx develops and sheds under healthy and diseased vascular conditions. I also work on endothelial mechanics and directional cell migration on different types of substrate, with the ultimate gold of understanding the process of vascular stiffening and aging.  +44 (0)20 7882 7821      wei-qi.li@qmul.ac.uk  Supervisor: Wen Wang

Dr William Megone Postdoctoral Research Assistant  w.v.megone@qmul.ac.uk  Supervisor: Julien Gautrot

Miss Maria Jose Munguia-Romero Research Assistant My early stage experience as a Textile Engineer is focused on product development in the fashion industry, specifically in SEMs clothing brands, based on sustainability principles.  m.j.mungua-romero@qmul.ac.uk  Supervisor: James Busfield

Dr Clémence Nadal PhD Postdoctoral Research Assistant My research aims at developing novel strategies to control the self-assembly and viscoelastic properties of hydrogels designed for regenerative medecine and/or tissue engineering purposes. Another aspect of my work focuses on the tuning of viscoelastic properties of protein nanosheets assembled at liquid-liquid interfaces and their characterization using interfacial rheology.  c.nadal@qmul.ac.uk  Supervisor: Julien Gautrot

Dr Sara Naderizadeh PhD Postdoctoral Research Assistant I am currently working on BFTT, or Business of Fashion, Textiles and Technology project, funded by AHRC-UKRI. This project is a five-year industry-led project, which focusses on delivering sustainable innovation within the entire fashion and textile supply chain. There are several academic and industrial partners around UK in this project. The main project that I involved is in collaboration with Nurvv company, to develop a wearable sensing technology that enables monitoring physical gait and body health with sports, ageing, and healthcare applications.  s.naderizadeh@qmul.ac.uk  Supervisor: James Busfield

Dr Elis Newham Postdoctoral Research Assistant Evolutionary biology, bioengineering, synchrotron X-ray tomographic imaging, Synchrotron SAXS, synchrotron WAXS  e.newham@qmul.ac.uk  Supervisor: Himadri Gupta

Dr Joanne Nolan PhD Centre Scientist, QM+Emulate Organs-on-Chips Centre I joined Queen Mary in 2021 working on an interdisciplinary CRUK-EPSRC funded project across both SEMS and Barts Cancer Institute. This work, in partnership with Emulate, focused on developing a new organ-on-a-chip model of breast cancer bone metastasis to study the interactions between breast cancer and bone cells. I currently manage the QM+Emulates Centre's suite of Human Emulation Systems with specialist training in the use of the platform. This involves leading the development of new models within the centre and providing support and training for research teams in the design, preparation and analysis of studies and development of research proposals.  joanne.nolan@qmul.ac.uk  Supervisor: Martin Knight

Dr David Shepherd MPhys, PhD KTP Research Associate Production and characterisation of hydroxyapatites. Cell Culture. Production of collagen scaffolds through Freeze Drying.  d.shepherd@qmul.ac.uk  Supervisor: Karin Hing

Dr Pamela Swiatlowska Postdoctoral Research Assistant Current research project is focused on studying regulation of mechanosensing in healthy and atherosclerotic vascular smooth muscle cells. This work involves number of techniques, such as mechanical stimulation (pressure, stiffness, stretch), biomechanical characterization (AFM, Nanoindentation), cellular force measurements (nanopillars, FRET tension sensors) as well as (live) super-resolution microscopy. Further expertise: fibroblast and cardiomyocyte mechanobiology from animal and human models.  p.swiatlowska@qmul.ac.uk  Supervisor: Thomas Iskratsch

Dr Danae Zamboulis DVM, PhD Visiting Postdoctoral Research Assistant I am a postdoctoral research associate with an interest in musculoskeletal biology and in particular the development of structure function in tendons. I completed a degree in Veterinary Medicine and an internship in Equine Medicine and Surgery from the Aristotle University of Thessaloniki, Greece, and subsequently undertook a PhD at the University of Liverpool. I have expertise in tendon biology, molecular biology techniques, proteomics and a good understanding of biomechanics.  d.zamboulis@qmul.ac.uk  Supervisor: Hazel Screen

Dr Hangfeng Zhang PhD Postdoctoral Research Assistant  hangfeng.zhang@qmul.ac.uk  Supervisor: Lei Su

Dr Bo Zhou Postdoctoral Research Assistant Photoelectrochemical imaging and sensing, Electrochemistry, Analytical chemistry, Surface chemistry, Functional metal oxides, Chemical vapor deposition, Boron-doped diamond, Advanced oxidation processes for wastewater treatment, Materials characterisation, Cell culture  bo.zhou@qmul.ac.uk  Supervisor: Steffi Krause

Dr Alexander Zolotarev PhD, MD Postdoctoral Research Associate Currently, Dr. Zolotarev is working on the project for designing optimal ablation therapy for atrial fibrillation through simulation and deep learning of digital twins. His research interests lie in the intersection between data science (computer vision and signal processing), and cardiology, particularly cardiac arrhythmias.  a.zolotarev@qmul.ac.uk  Supervisor: Caroline Roney

Professional Services

Current PhD Projects

Thesis Title	Supervisor
Study of Liquid-liquid interfaces	Julien Gautrot
Modelling pregnancy outcomes to prevent preterm birth after exposure to air pollution during Covid19	Tina Chowdhury
INVESTIGATION OF THE CEMENT MANTLE STRESS IN THE ACETABULAR COMPONENT AFTER TOTAL HIP ARTHROPLASTY (THA)	Teresa Alonso-Rasgado
3D in vitro models; biofabrication; 3D bioprinting;	Thomas Iskratsch
Nanoscale damage markers for early osteoarthritis detection in the bone-cartilage unit	Himadri Gupta
Biophysical biomarkers to characterize cancer-associated fibroblasts in breast cancer	Martin Knight
Prostate Cancer Detection	Zion Tse
Study of ion responsive polymer brushes as smart coatings and physical gels models	Julien Gautrot
organ chip model development- - integrating mechanobiology	Hazel Screen
Exploring tendon health and disease with tendon-on-a-chip models	Hazel Screen
Engineering retinal vascularization on a chip to model pathological events in eye diseases and study the effect of modulator drugs	Julien Gautrot
Protein nanosheet engineering, bioemulsion design and application in stem cell technologies	Julien Gautrot
2022 EPSRC DTP TC	Tina Chowdhury
Development of a Polycystic Kidney Disease organ-chip model to study therapeutic regulation of primary cilia mechanobiology	Martin Knight
Design of an organ-on-a-chip model of soft-hard tissue interfaces	Julien Gautrot
High throughput analysis of mechanosensitive microRNA	Rob Krams
Taper Junctions in modular total hip arthroplasty	Julia Shelton
Lifetime predictions of Elastomers	James Busfield
Development of an Organ-chip Model to examine Muscle Degeneration	Hazel Screen
Nanoscale biophysics of cutaneous fibrosis	Himadri Gupta
Long-term Tracking and Targeted Therapy of Mesenchymal Stem Cell Labeled Nanoparticles	Martin Knight
Novel Models of Tendinopathy on a Chip	Hazel Screen
Investigation of optimal bone coverage for the adequate fixation of the acetabular cup in patients with Developmental Dysplasia of the Hip during uncemented Total Hip Arthroplasty	Teresa Alonso-Rasgado
Modelling and characterisation of cells in flows	Yi Sui
Ion channel blockers effect on viability, cell migration and	Lei Su
Microdroplet-based microfluidics for direct reprogramming of human pluripotent stem cells	Julien Gautrot
Optical sensing for in-vivo imaging	Lei Su
Development of an arterial organ-chip to study the role of primary cilia in atherosclerosis	Martin Knight
Smart Medical Robotic Devices for Diagnosis and Treatment	Zion Tse
CSC/Visiting student	Julien Gautrot
Development of a new High Throughput CRISPR platform for detection of microRNA	Rob Krams
In-situ optical and electrochemical imaging system for 3D in vitro models and in-vivo applications	Steffi Krause
A Cohort of Virtual Human Atria with Personalised Electrophysiology for In-silico Prediction of Ablation and Pharmacology Therapy Outcome	Caroline Roney
Developing a CRISPR Methodology for subtle modification of proteins in mammalian cells	Rob Krams
Healthcare Robotics and MedTech	Zion Tse
AI-driven surgical inventory management to prevent waste in healthcare	Zion Tse
Organ-on-a-chip model of cartilage disease	Martin Knight
Biophysics of Self-Assembled Protein Nanosheets for Stem Cell-Based Biotechnologies	Julien Gautrot
Tyre Degradation Performance - SRI	James Busfield
miRNAS Sequence Embedding For Pathway Detection And Selectivity	Rob Krams
The Role of Proteoglycans in Vascular Smooth Muscle Mechanosensing	Thomas Iskratsch
Bioresorbable Bioactive Composites	Karin Hing
Carbon black reinforcement of tyre tread compounds	James Busfield
Engineered Recombinant Strategies to Organo-Hydrogel Design with Applications from Plant-Based Foods to Tissue Engineering	Julien Gautrot
Smart Medical Robotic Devices for Diagnosis and Treatment	Zion Tse
Numerical Modelling of Cancer cells in flows	Yi Sui
Investigation of mechanobiological sensing in cell spreading	Steffi Krause
The combination of fluorescent AuNCs and microcapsules	Gleb Sukhorukov
Flexible ultrasound sensor	Lei Su
MRI Conditional Actuations and Prostate Intervention Systems	Zion Tse
Magnetically Actuated Robots for Medical Interventions	Zion Tse
Investigating the Effects of Catheter Electrode Arrangement	Caroline Roney
Physics-based AI to identify atherosclerosis progression	Rob Krams
Design of synthetic nanostructured hydrogel to regulate microvascularisation	Julien Gautrot
The role of YAP and primary cilia in regulating inflammatory responses of cartilage	Martin Knight
Sustainable Future Footwear and Fashion Technology	James Busfield
Engineered Bone Bioengineered Interface to model osteolytic breast cancer metastatic niche	Elizabeth Tanner
Design of polymer brush vectors for controlled RNA delivery.	Julien Gautrot
Smart Medical Robotic Devices for Diagnosis and Treatment	Zion Tse
IL-10 signalling in human vascular development (human vascular cell differentiation from induced-pluripotent stem cell (iPSC))	Wen Wang
Filler Reinforcement of Elastomers	James Busfield
Nanotechnology approaches for the investigation of cardiac mechanosensing	Thomas Iskratsch
Optimisation of a Novel Polymeric Heart Valve	James Busfield
Control of the Circadian Clock in Chondrocytes	David Lee
The interfascicular matrix niche ? novel approaches to identify the aetiology of tendinopathy	Hazel Screen
Optimisation of Tyre Wear Performance	James Busfield
A Dynamic Model of Soft Tissue Integration to Dental Hard Tissue	Thomas Iskratsch
3D enhanced bioreactor for enhanced bone grafting	Karin Hing
Development of a new causal AI framework for genomics research	Rob Krams
Nanostructured Reinforcing Fillers to Enhance Physical and Mechanical Properties	James Busfield
A parallel-processing portable functional electrical stimulation device for patients with foot drop	Teresa Alonso-Rasgado
A Single Cell Analysis Approach for Viscoelastic Characterization Using Microfluidics.	Yi Sui
Graphene based transparent electrodes for tuneable optical devices	James Busfield
Hydrogel Waveguides for Clinical Applications	Lei Su
Innovative Tactile and Optical Sensing and Actuating Devices	James Busfield
Perovskite light emitting devices	Lei Su
Polymer brushes as a delivery tool to DNA vaccine	Julien Gautrot
Smart Medical Robotic Devices for Diagnosis and Treatment	Zion Tse
Links between environmental air pollution, PPROM and preterm birth	Tina Chowdhury
Designing Mechanism-Specific Treatment Approaches for Atrial Fibrillation Through Computational Modelling	Caroline Roney
Role of CD34+ Stem Cells in Isografted Vessel Remodelling	Wen Wang
Wafer-Scale Manufacturing of Single-Crystal Perovskite Optoe	Lei Su
Deep learning assisted optical sensing	Lei Su
Single optical fibre imaging	Lei Su
Cardiomyocytes, Mechanobiology, Rigidity sensing, Micropatterning, Traction Force Measurement	Thomas Iskratsch
Organo-Hydrogel Design with Applications	Julien Gautrot
3D photoelectrochemical imaging	Steffi Krause
Development of organ-chip models of the growth plate with mechanical stimulation	Martin Knight

Past PhD Projects

Thesis Title	Supervisor	Year
Electrospinning high toughness biomimetic polystyrene nanocomposites	Asa Barber, Himadri Gupta	2017
The Effects of Loading Frequency on Tenocyte Matabolism	Hazel Screen	2017
Fabrication of non(low) permeable microcapsules and further study	Gleb Sukhorukov, Himadri Gupta	2017
SmartNanoHeat - Self-regulating heating compounds	Emiliano Bilotti, James Busfield	2017
Motion of deformable capsules in complex flows	Yi Sui	2017
Wear and corrosion testing of modular hip prostheses	Julia Shelton	2017
Micro-patterning of peptide-based biomaterials	Julien Gautrot, Hazel Screen	2017
Electric Breakdown of Dielectric Elastomer Actuator Materials	Federico Carpi, James Busfield	2017
Fatigue life prediction in aircraft tyres	James Busfield	2017
Development of materials and applications for electroactive composites	James Busfield, Federico Carpi	2017
Predicting tyre compound wear.	James Busfield, Emiliano Bilotti	2017
Composite inorganic particles/polyelectrolyte microcapsules: fabrication and application	Gleb Sukhorukov	2017
Interaction between the circulating blood and vascular endothelial cells in health & disease. Cell Mechanics for endothelial glycocalyx	Wen Wang, Asa Barber	2016
Development of a 3D Perfusion System to Monitor Response of Osteoblast-like Cells Incubated on Synthetic Bone Graft Substitute Granules with Varied Hierarchical Porosities under Dynamic Conditions	Karin Hing	2016
The role of HDAC7-related peptide in stem cell differentiation towards endothelial cell	Wen Wang	2016
The synergistic role of mechanical stimuli and VEGF treatment in stem cell differentiation to endothelial cells	Wen Wang	2016
The effects of the rate of hypo-osmotic challenge and IFT88 mutation on the biomechanics of chondrocytes.	Martin Knight, Wen Wang	2016
Roles of primary cilia in hMSC in differentiation	Martin Knight	2016
Investigating the effects of cholesterol on phospholipid bilayer with molecular dynamics simulations.	Wen Wang, Yiling Lu	2016
Biomimetic Layered Nanocomposites with Tunable Dynamical Mechanical Properties: Synthesis, Imaging and Characterisation	Himadri Gupta, Nicola Pugno	2016
Micro-structure reorganisation of the aortic heart valve under a biaxial loading condition	Hazel Screen, Wen Wang	2016
A novel fibre composite system to investigate tenocyte metabolism under physiological and pathological loading conditions.	Hazel Screen	2016
The Strain Dependent Dielectric Behaviour of Carbon Black Filled Natural Rubber	James Busfield, Emiliano Bilotti	2016
Developing Cationic Nanoparticles for Gene Delivery	Julien Gautrot, John Stark	2016
Naturally Inspired Multi-layer Composite Films on Planar and Modulated Surfaces	Gleb Sukhorukov, Ton Peijs	2016
Bone Quality Changes at the Nanoscale in Metabolic Bone Diseases assessed by Synchrotron X-ray Imaging	Himadri Gupta	2016
To Fabricate and Study the Properties of the Intelligent Microencapsulated Liquid Particles Containing Biologically Active Compounds	Gleb Sukhorukov	2016
Complex mechanical conditioning of cell-seeded constructs can influence chondrocyte activity	Julia Shelton, Dan Bader	2015
Microcapsule for targetted drug delivery to diseased tissues	Wen Wang, Gleb Sukhorukov	2015
Mechanical properties of stem cells using micropipette aspiration	Martin Knight, David Lee	2015
Combined Impedance and Fluorescence Imaging of Polymeric Microcapsules using Photocurrent Measurements at silicon/SAM/electrolyte Field Effect Structures	Steffi Krause	2015
Microfluidics for a novel bioreactor	Wen Wang, Pankaj Vadgama	2015
Investigation of Protein Mediated Control of Oteoinductivity in Porous Bone Graft Substitutes using Fluorescent Probes	Karin Hing, Alice Sullivan	2015
Functional impact of microRNA-34a on stem cell differentiation towards smooth muscle cell	Wen Wang	2015
The Role of DKK3 in Vascular Smooth Muscle Differentiation	Wen Wang	2015
Monitoring of Bone Quality and Penetration in Osteoinductive Scaffolds with Varied Strut Porosity	Karin Hing	2015
Enhancing Osteogenesis in Porous Bone Graft Substitutes Through Control of Microporosity	Karin Hing	2015
Electrical stimulation on cell-cell interactions in vitro	Wen Wang	2015
The development of a novel nanostructured silica filler for high friction and low rolling resistance rubber applications.	James Busfield	2015
Accelerated wear protocols for understanding clinical wear in modern hip prostheses	Julia Shelton, Martin Knight	2014
Novel polymeric matrix and its interaction withbiological cells	Wen Wang, Ton Peijs	2014
Failure of Rubber Components under Fatigue	James Busfield	2014
Microcapsule internalization be cells in vitro caused by physical and biochemical stimuli	Gleb Sukhorukov, Wen Wang	2014
The behaviour of hollow sphere filled rubber materials under strain	James Busfield	2014
A Biomechanical Characterisation of Eccentric and Concentric Loading of the Triceps Surae Complex	Hazel Screen	2013
Tearing of rubber	James Busfield	2013
UV-Triggered Encapsulation and Release by Multilayer Microcapsules	Gleb Sukhorukov	2013
The Nanostructure of Impant-Induced Fibrosis (MPhil)	Himadri Gupta	2013
Interaction between primary cilia length and hedgehog signalling in response to mechanical and thermal stress	Martin Knight	2013
Nuclear Related Responses to Osmotic Challenge in Chondrocytes	David Lee, Martin Knight	2013
Analysis of Alterations in Matrix Quality at Nanoscale in Metabolic Bone Diseases using Synchrotron X-ray Diffraction	Himadri Gupta	2013
Investigation into the use of carbon nanotubes networks as gate electrodes in field-effect gas sensors with increased functionality	Steffi Krause	2013
Modelling studies on biological tissue property and mechanical responses under external stimuli	Wen Wang	2012
Spatial distribution, temporal development and mechanical properties of the endothelial glycocalyx in vitro	Wen Wang	2012
Multilayer Microcapsules for Delivery, Control and Triggered Release of Bioactive Compounds	Gleb Sukhorukov	2012
Laser scanning system for microscopic and macroscopic investigations of chemical semiconductor sensors	Steffi Krause	2012
The Impact and Deformation of Press-Fit Metal Acetablular Components	Julia Shelton, James Busfield	2012
Natural Rubber/Organoclay Nanocomposites	James Busfield	2012
Novel Fluorescent probes for Analysis of Protein interactions under truly physiological conditions with real Medical devices	Karin Hing	2012
Viscoelastic Response of Cells and the Role of Actin Cytoskeletal Remodelling	Martin Knight	2012
Structure-Function Relationships in the Aortic Valve	Hazel Screen	2012
Influence of coatings on ion release from large diameter metal-on-metal hip bearings	Julia Shelton	2012
Computational modelling of flows in porous scaffold materials using a lattice Boltzmann method	Wen Wang	2011
microRNAs play a role in human embryonic stem cell differentiation into endothelial cells	Wen Wang	2011
Can Interface Conditions be Modified by Support Surfaces to Minimise the Risk of Pressure Ulcer Development?	Wen Wang, Dan Bader	2011
Development of a non-invasive method to detect pericellular spatial oxygen gradients using FLIM	Martin Knight	2011
Processing of Polymer-based Systems for Improved Performance and Controlled Release	Gleb Sukhorukov, Ton Peijs	2011
The influence of test parameters and surface modifications on the wear of total hip replacements	Julia Shelton	2011
Investigation and Modelling of Rubber Friction	James Busfield	2010
The Influence of Microstructure on the Mechanical Behaviours of Tendons	Hazel Screen, Julia Shelton	2010
Characterisaction of Human Mesenchymal Stem Cell Metabolism during Proliferation and Differentiation	David Lee, Joost deBruijn	2010
Viscoelastic Properties of Elastomer under Complex Loading	James Busfield	2010
Carbon Black Filler Reinforcement of Elastomers	James Busfield	2009
The potential of pulsed low-intensity ultrasound to stimulate chondrocytes in a 3D model system	Martin Knight	2009
Optically addressable, integrative composite polymer microcapsules	Gleb Sukhorukov	2009
Novel biosensors and Their application in Mass Transport	Wen Wang, Pankaj Vadgama	2009
Investigation into the Sensitivity and Resolution of Scanning Photo-Induced Impedance Microscopy	Steffi Krause	2009
In vitro wear of metal-on-metal hip replacements: a multifactorial problem.	Julia Shelton	2008
The influence of direct current electrical stimulation on chondrocytes in a 3D model system	Dan Bader, David Lee	2008
Mechanisms of the improvced Biological Response with Silicate Substitution in Hydroxy Apatite.	Karin Hing	2008
Temporal regulation of tenocyte metabolism in strained fascicles	David Lee, Julia Shelton	2008