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January 2021

Group photo: Fan Li with Profs. Lockerby, Smoukov and Karabasov

Fan Li Passes his PhD Viva on "Non-equilibrium and hybrid multiscale modelling of molecular systems"

19 January 2021

Many congratulations to Fan Li for successfully passing his PhD Viva with minor corrections on the dissertation “Non-equilibrium and hybrid multiscale modelling of molecular systems”. The Viva was held remotely by Teams. Many problems in science and engineering comprise multiple scales in space and time. A particular example is micro … [more]

CR UK & EPSRC Multidisciplinary Award

New CRUK/EPSRC research grant: Organ-on-a-chip model to investigate breast cancer bone metastases

12 January 2021

A new research grant using organ-on-a-chip technology to understand breast cancer bone metastasis has started in Prof Martin Knight's bioengineering and mechanobiology research group. The multidisciplinary award is jointly funded by Cancer Research UK (CR UK) and the Engineering and Physical Sciences Research Council (EPSRC). The project will develop a … [more]

Image showing live cells in cartilage tissue and the anti-inflammatory effects of TRPV4 activation with GSK101 which prevents biomechanical degradation.

New paper on anti-inflammatory effects of TRPV4 stimulation

11 January 2021

Prof Knight's research group have published a new study showing, for the first time, the anti-inflammatory effects of stimulating the mechanosensitive ion-channel, TRPV4, and it's importance in cartilage health. Degenerative joint conditions, such as osteoarthritis, are associated with pro-inflammatory signalling which causes degradation of the articular cartilage leading to stiff … [more]