Prof David Lee
BSc (Hons), MA, PhD
All Publications
Page 1 of 5
2022
- Heywood HK, Thorpe SD, Jeropoulos RM, Caton PW and Lee DA (2022). Modulation of sirtuins during monolayer chondrocyte culture influences cartilage regeneration upon transfer to a 3D culture environment. Frontiers in Bioengineering and Biotechnology, Frontiers Media vol. 10
06-12-2022 - Heywood HK, Gardner L, Knight MM and Lee DA (2022). Oscillations of the circadian clock protein, BMAL-1, align to daily cycles of mechanical stimuli: a novel means to integrate biological time within predictive in vitro model systems. In Vitro Models, Springer Nature, 1-8.
31-08-2022 - Brookes O, Thorpe SD, Evans OR, Keeling MC and Lee DA (2022). Covariation of Pluripotency Markers and Biomechanical Properties in Mouse Embryonic Stem Cells. Frontiers in Cell and Developmental Biology, Frontiers vol. 10
16-05-2022
2021
- Lachowski D, Cortes E, Matellan C, Rice A, Lee DA, Thorpe SD and del Río Hernández AE (2021). G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell Polarization. Frontiers in Cell and Developmental Biology, Frontiers Media vol. 8, 592628-592628.
22-01-2021
2020
- Rice A, Cortes E, Lachowski D, Oertle P, Matellan C, Thorpe SD, Ghose R, Wang H, Lee DA, Plodinec M and Del Río Hernández AE (2020). GPER activation inhibits cancer cell mechanotransduction and basement membrane invasion via RhoA. Cancers, Mdpi Ag vol. 12 (2)
25-01-2020 - Thorpe S, Chronopoulos A, Cortes E, Lachowski D, Rice A, Mykuliak V, Róg T, Lee D, Hytonen V and del Río Hernández A (2020). Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway. Nature Materials, Nature Research
06-01-2020
2018
- Cortes E, Lachowski D, Rice A, THORPE SD, Robinson B, Yeldag G, LEE DA, Ghemtio L, Rombouts K and del Río Hernández AE (2018). Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor. Oncogene, Springer Nature [Academic Journals On Nature.Com]
21-12-2018 - Cortes E, Lachowski D, Robinson B, Sarper M, Teppo JS, Thorpe SD, Lieberthal TJ, Iwamoto K, Lee DA, Okada‐Hatakeyama M, Varjosalo MT and Hernández AER (2018). Tamoxifen mechanically reprograms the tumor microenvironment via HIF‐1A and reduces cancer cell survival. Embo Reports, Springer Nature vol. 20 (1)
12-12-2018 - Cortes E, Sarper M, Robinson B, Lachowski D, Chronopoulos A, Thorpe SD, Lee DA and Hernández AER (2018). GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment. Embo Reports, Springer Nature vol. 20 (1)
11-12-2018 - Cortes E, Lachowski D, Rice A, Chronopoulos A, Robinson B, THORPE SD, LEE DA, Possamai LA, Wang H, Pinato DJ and del Rio Hernández AE (2018). RAR‐β is downregulated in HCC & cirrhosis and its expression inhibits myosin‐driven activation and durotaxis in hepatic stellate cells. Hepatology, Wiley
28-07-2018
2017
- Elyasigomari V, Lee DA, Screen HRC and SHAHEED MH (2017). Development of a two-stage gene selection method that incorporates a novel hybrid approach using the cuckoo optimization algorithm and harmony search for cancer classification. Journal of Biomedical Informatics vol. 67 (2017), 11-20.
03-02-2017 - THORPE SD and Lee DA (2017). Dynamic regulation of nuclear architecture and mechanics—a rheostatic role for the nucleus in tailoring cellular mechanosensitivity. Nucleus, Taylor & Francis vol. 8 (3), 287-300.
02-02-2017
2016
- Heo S-J, Driscoll TP, Thorpe SD, Nerurkar NL, Baker BM, Yang MT, Chen CS, Lee DA and Mauck RL (2016). Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity. Elife, Elife Sciences Publications Ltd vol. 5
30-11-2016 - Tilwani RK, Vessillier S, Pingguan-Murphy B, Lee DA, Bader DL and Chowdhury TT (2016). Oxygen tension modulates the effects of TNFα in compressed chondrocytes. Inflamm Res
22-09-2016 - Heo SJ, Han WM, Szczesny SE, Cosgrove BD, Elliott DM, Lee DA, Duncan RL and Mauck RL (2016). Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells. Biophysical Journal vol. 111 (4), 864-874.
23-08-2016 - Heywood HK and Lee DA (2016). Bioenergetic reprogramming of articular chondrocytes by exposure to exogenous and endogenous reactive oxygen species and its role in the anabolic response to low oxygen. Journal of Tissue Engineering and Regenerative Medicine vol. 11 (8), 2286-2294.
22-06-2016 - Sliogeryte K, Botto L, Lee DA and Knight MM (2016). Chondrocyte dedifferentiation increases cell stiffness by strengthening membrane-actin adhesion. Osteoarthritis and Cartilage, Elsevier vol. 24 (5), 912-920.
01-05-2016 - Lee D (2016). States rights and Australia’s adoption of the statute of Westminster, 1931–1942. History Australia, Taylor & Francis vol. 13 (2), 258-274.
02-04-2016 - Theocharidis G, Drymoussi Z, Kao AP, Barber AH, Lee DA, Braun KM and Connelly JT (2016). Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility. Journal of Investigative Dermatology, Elsevier vol. 136 (1), 74-83.
01-01-2016 - Theocharidis G, Drymoussi Z, Kao AP, Barber AH, Lee DA, Braun KM and Connelly JT (2016). Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility. J Invest Dermatol vol. 136 (1), 74-83.
01-01-2016
2015
- Heo S-J, Thorpe SD, Driscoll TP, Duncan RL, Lee DA and Mauck RL (2015). Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells. Scientific Reports, Springer Nature vol. 5 (1)
23-11-2015 - CHEN J, BADER DL, LEE DA and KNIGHT MM (2015). FINITE ELEMENT ANALYSIS OF MECHANICAL DEFORMATION OF CHONDROCYTE TO 2D SUBSTRATE AND 3D SCAFFOLD. Journal of Mechanics in Medicine and Biology, World Scientific Publishing vol. 15 (05)
01-10-2015
2014
- Sliogeryte K, Thorpe SD, Lee DA, Botto L and Knight MM (2014). Stem cell differentiation increases membrane-actin adhesion regulating cell blebability, migration and mechanics. Scientific Reports, Springer Nature vol. 4 (1)
04-12-2014 - Irianto J, Lee DA and Knight MM (2014). Quantification of chromatin condensation level by image processing. Med Eng Phys vol. 36 (3), 412-417.
01-03-2014 - Heywood HK, Nalesso G, Lee DA and Dell'accio F (2014). Culture expansion in low-glucose conditions preserves chondrocyte differentiation and enhances their subsequent capacity to form cartilage tissue in three-dimensional culture. Biores Open Access vol. 3 (1), 9-18.
01-02-2014
2013
- Irianto J, Swift J, Martins RP, McPhail GD, Knight MM, Discher DE and Lee DA (2013). Osmotic challenge drives rapid and reversible chromatin condensation in chondrocytes. Biophys J vol. 104 (4), 759-769.
19-02-2013 - Pattappa G, Thorpe SD, Jegard NC, Heywood HK, de Bruijn JD and Lee DA (2013). Continuous and Uninterrupted Oxygen Tension Influences the Colony Formation and Oxidative Metabolism of Human Mesenchymal Stem Cells. Tissue Engineering Part C-Methods vol. 19 (1)
01-01-2013 - Lee D (2013). Reluctant relaxation. History Australia, Taylor & Francis vol. 10 (3), 149-170.
01-01-2013
2012
- Sillitoe I, Cuff AL, Dessailly BH, Dawson NL, Furnham N, Lee D, Lees JG, Lewis TE, Studer RA, Rentzsch R, Yeats C, Thornton JM and Orengo CA (2012). New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures. Nucleic Acids Research, Oxford University Press (Oup) vol. 41 (D1), d490-d498.
29-11-2012 - Chen J, Irianto J, Inamdar S, Pravincumar P, Lee DA, Bader DL and Knight MM (2012). Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment. Biophys J vol. 103 (6), 1188-1197.
19-09-2012 - Bonzani IC, Campbell JJ, Knight MM, Williams A, Lee DA, Bader DL and Stevens MM (2012). Dynamic compressive strain influences chondrogenic gene expression in human periosteal cells: a case study. J Mech Behav Biomed Mater vol. 11, 72-81.
01-07-2012 - Branford OA, Lee DA, Rolfe KJ and Grobbelaar AO (2012). The attachment of intrinsic and extrinsic, mobilized and immobilized adhesion cells to collagen and fibronectin. Journal of Hand Surgery: European Volume vol. 37 (6), 564-572.
01-07-2012 - Branford OA, Lee DA, Bader DL and Grobbelaar AO (2012). The mechanics of flexor tendon adhesions. Journal of Hand Surgery: European Volume vol. 37 (6), 555-563.
01-07-2012 - Lee D, Smallbone K, Dunn WB, Murabito E, Winder CL, Kell DB, Mendes P and Swainston N (2012). Improving metabolic flux predictions using absolute gene expression data. Bmc Systems Biology, Springer Nature vol. 6 (1)
19-06-2012 - Maeda E, Ye S, Wang W, Bader DL, Knight MM and Lee DA (2012). Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading. Biomechanics and Modeling in Mechanobiology vol. 11 (3-4), 439-447.
01-03-2012 - Lee D (2012). Stanley Melbourne Bruce in London, 1938–41. The Journal of Imperial & Commonwealth History, Taylor & Francis vol. 40 (1), 45-65.
01-03-2012 - Gutowski IA, Lee D, de Bruyn JR and Frisken BJ (2012). Scaling and mesostructure of Carbopol dispersions. Rheologica Acta, Springer Nature vol. 51 (5), 441-450.
18-01-2012 - Martins RP, Finan JD, Guilak F and Lee DA (2012). Mechanical regulation of nuclear structure and function. Annu Rev Biomed Eng vol. 14, 431-455.
01-01-2012 - Hosny NA, Lee DA and Knight MM (2012). Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations. J Biomed Opt vol. 17 (1)
01-01-2012
2011
- Jaimes N, Scope A, Welzel J, Wang KX, Lee DA, Siegel DM and Marghoob AA (2011). White Globules in Melanocytic Neoplasms: In Vivo and Ex Vivo Characteristics. Dermatologic Surgery, Wolters Kluwer vol. 38 (1), 128-132.
31-10-2011 - Pattappa G, Heywood HK, de Bruijn JD and Lee DA (2011). The metabolism of human mesenchymal stem cells during proliferation and differentiation. J Cell Physiol vol. 226 (10), 2562-2570.
01-10-2011 - Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH and Screen HRC (2011). Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment. Proc Inst Mech Eng H vol. 225 (8), 821-830.
01-08-2011 - Moses SE, Osborne W, Valappil M, Collin M, Lee D, Waugh S, Jackson G, Parry CM and Crowley B (2011). Extensive oral herpes simplex virus type 1 infection in a haematopoietic stem cell transplant recipient not responding to aciclovir. Journal of Clinical Virology, Elsevier vol. 52 (2), 67-69.
14-06-2011 - Lee D, Gutowski IA, Bailey AE, Rubatat L, de Bruyn JR and Frisken BJ (2011). Investigating the microstructure of a yield-stress fluid by light scattering. Physical Review E, American Physical Society (Aps) vol. 83 (3)
01-03-2011 - Lee D, de Beer TA, Laskowski RA, Thornton JM and Orengo CA (2011). 1,000 structures and more from the MCSG. Bmc Molecular and Cell Biology, Springer Nature vol. 11 (1)
01-01-2011 - Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH and Screen HRC (2011). Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment. P I Mech Eng H vol. 225 (H8), 821-830.
01-01-2011 - Martyn SV, Heywood HK, Rockett P, Paine MD, Wang MJ, Dobson PJ, Sheard SJ, Lee DA and Stark JPW (2011). Electrospray deposited fibronectin retains the ability to promote cell adhesion. Journal of Biomedical Materials Research - Part B Applied Biomaterials vol. 96 B (1), 110-118.
01-01-2011 - Maeda E, Ye S, Wang W, Bader DL, Knight MM and Lee DA (2011). Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading. Biomechanics and Modeling in Mechanobiology, 1-9.
01-01-2011 - Lee DA and Siegel DM (2011). Novel devices for diagnosis and treatment. Journal of Drugs in Dermatology vol. 10 (1), 21-22.
01-01-2011 - Lee DA, Brand J, Salter D, Akanji O-O and Chowdhury TT (2011). Quantification of mRNA using real-time PCR and Western blot analysis of MAPK events in chondrocyte/agarose constructs. Methods Mol Biol vol. 695, 77-97.
01-01-2011