Prof David Lee
BSc (Hons), MA, PhD

 

All Publications

Page 2 of 5

    2011

    2010

    • Pattappa G, Heywood HK, de Bruijn JD and Lee DA (2010). The metabolism of human mesenchymal stem cells during proliferation and differentiation. J Cell Physiol 
      28-12-2010
    • Maeda E, Fleischmann C, Mein CA, Shelton JC, Bader DL and Lee DA (2010). Functional analysis of tenocytes gene expression in tendon fascicles subjected to cyclic tensile strain. Connective Tissue Research vol. 51 (6), 434-444.  
      01-12-2010
    • Heywood HK, Knight MM and Lee DA (2010). Both superficial and deep zone articular chondrocyte subpopulations exhibit the crabtree effect but have different basal oxygen consumption rates. Journal of Cellular Physiology vol. 223 (3), 630-639.  
      01-06-2010
    • Lee D (2010). Giving something back. Twist (22), 28-30.  
      01-06-2010
    • Ye S, Maeda E, Knight M, Lee D, Bader D and Wang W (2010). A compartment model to evaluate the permeability of gap junctions between tenocytes in tendon fascicles. Faseb Journal vol. 24 
      01-01-2010
    • Heywood HK and Lee DA (2010). Low oxygen reduces the modulation to an oxidative phenotype in monolayer-expanded chondrocytes. J Cell Physiol vol. 222 (1), 248-253.  
      01-01-2010

    2009

    • Maeda E, Shelton JC, Bader DL and Lee DA (2009). Effect of intermittent cyclic tensile strain on collagen synthesis by tenocytes in isolated fascicles. Journal of Biomechanical Science and Engineering vol. 4 (4), 510-517.  
      01-12-2009
    • Lee DA, Rentzsch R and Orengo C (2009). GeMMA: functional subfamily classification within superfamilies of predicted protein structural domains. Nucleic Acids Research, Oxford University Press (Oup) vol. 38 (3), 720-737.  
      18-11-2009
    • Pattappa G, Jegard NC, Lee DA and de Bruijn JD (2009). The effect of oxygen tension on the proliferation and differentiation of human mesenchymal stem cells. European Cells and Materials vol. 18 (SUPPL. 1) 
      01-08-2009
    • Campbell JJ, Maeda E, Ye SJ, Wang W and Lee DA (2009). Osteogenic differentiation of human mesenchymal stem cells within a perfused bioreactor system. European Cells and Materials vol. 18 (SUPPL. 2) 
      01-07-2009
    • Pattappa G, Jegard NC, de Bruijn JD and Lee DA (2009). The influence of oxygen tension on the colony formation and proliferation of human mesenchymal stem cells. European Cells and Materials vol. 18 (SUPPL. 2) 
      01-07-2009
    • Maeda E, Shelton JC, Bader DL and Lee DA (2009). Differential regulation of gene expression in isolated tendon fascicles exposed to cyclic tensile strain in vitro. Journal of Applied Physiology vol. 106 (2), 506-512.  
      01-02-2009
    • Berry CC, Shelton JC and Lee DA (2009). Cell-generated forces influence the viability, metabolism and mechanical properties of fibroblast-seeded collagen gel constructs. J Tissue Eng Regen Med vol. 3 (1), 43-53.  
      01-01-2009
    • Eniwumide JO, Lee DA and Bader DL (2009). The development of a bioreactor to perfuse radially-confined hydrogel constructs: design and characterization of mass transport properties. Biorheology vol. 46 (5), 417-437.  
      01-01-2009

    2008

    • Pattappa G, A. Lee D and De Bruijn JD (2008). Metabolic characteristics of human mesenchymal stem cells expanded under normoxic conditions. 8th World Biomaterials Congress 2008 vol. 1 
      01-12-2008
    • Lee D and Schroeder J (2008). Phenotypic analysis of Arabidopsis mutants: heavy metal stress. Cold Spring Harbor Protocols, Cold Spring Harbor Laboratory vol. 2008 (9) 
      01-09-2008
    • Heywood HK and Lee DA (2008). Monolayer expansion induces an oxidative metabolism and ROS in chondrocytes. Biochem Biophys Res Commun vol. 373 (2), 224-229.  
      22-08-2008
    • Maeda E, Shelton JC, Bader DL and Lee DA (2008). Collagen synthesis by tenocytes in fascicles subjected to intermittent cyclic strain. European Cells and Materials vol. 16 (SUPPL. 3) 
      01-07-2008
    • Chowdhury TT, Salter DM, Bader DL and Lee DA (2008). Signal transduction pathways involving p38 MAPK, JNK, NF kappa B and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1 beta and dynamic compression. Inflamm Res vol. 57 (7), 306-313.  
      01-07-2008
    • Heywood HK and Lee DA (2008). The effect of oxygen supply on chondrocyte metabolic phenotype during monolayer culture. European Cells and Materials vol. 16 (SUPPL. 3) 
      01-07-2008
    • Hughes D, Whitaker Y, Lee D and Eckhause J (2008). Advantages, Disadvantages, and Uses of Generalized Activity Networks for Schedule Estimation. Military Operations Research, Military Operations Research Society vol. 13 (3), 27-40.  
      01-06-2008
    • Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Bader DL, Salter DM and Lee DA (2008). Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs. Arthritis Res Ther vol. 10 (2) 
      01-01-2008
    • Chowdhury TT, Akanji OO, Salter DM, Bader DL and Lee DA (2008). Dynamic compression influences interleukin-1 beta-induced nitric oxide and prostaglandin E-2 release by articular chondrocytes via alterations in iNOS and COX-2 expression. Biorheology vol. 45 (3-4), 257-274.  
      01-01-2008
    • Campbell JJ, Bader DL and Lee DA (2008). Mechanical loading modulates intracellular calcium signaling in human mesenchymal stem cells. J Appl Biomater Biom vol. 6 (1), 9-15.  
      01-01-2008
    • Lee DA (2008). Surgeons carry out first implant of pulmonary human heart valve. Biomedical Materials (MAY) 
      01-01-2008

    2007

    • Chowdhury TT, Akanji OO, Arghandawi S, Salter DM, Bader DL and Lee DA (2007). 52 REAL-TIME PCR USING MOLECULAR BEACONS TO DETECT INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS SUBJECTED TO IL-1β AND DYNAMIC COMPRESSION. Osteoarthritis and Cartilage, Elsevier vol. 15, c42-c43.  
      01-12-2007
    • Lee D, Redfern O and Orengo C (2007). Predicting protein function from sequence and structure. Nature Reviews Molecular Cell Biology, Springer Nature vol. 8 (12), 995-1005.  
      01-12-2007
    • Chen Y-H, Chang H-H, Chen Y-J, Lee D, Chiang H-H and Jane Yao C-C (2007). Root contact during insertion of miniscrews for orthodontic anchorage increases the failure rate: an animal study. Clinical Oral Implants Research, Wiley, 07102500154-???.  
      23-10-2007
    • Maeda E, Shelton JC, Bader DL and Lee DA (2007). Time dependence of cyclic tensile strain on collagen production in tendon fascicles. Biochem Biophys Res Commun vol. 362 (2), 399-404.  
      19-10-2007
    • Lee DA (2007). Industry news: CryoLife signs Irish distribution deal with Proxy Biomedical. Biomedical Materials (NOV.), 6-7.  
      01-01-2007
    • Lee DA and Hall J (2007). Products: CryoLife wins rights to distribute replacement pericardium. Biomedical Materials (MAR.) 
      01-01-2007
    • Lee DA (2007). Products: CryoLife wins US patent for foam wound sealant. Biomedical Materials (JULY) 
      01-01-2007

    2006

    • Heywood HK, Bader DL and Lee DA (2006). Glucose Concentration and Medium Volume Influences Cell Viability and Glycosaminoglycan Synthesis in Chondrocyte-Seeded Alginate Constructs. Tissue Engineering, Mary Ann Liebert 
      20-11-2006
    • Gao J, Yang Y, Lee D, Holdcroft S and Frisken BJ (2006). Self-Assembly of Latex Particles into Proton-Conductive Membranes. Macromolecules, American Chemical Society (Acs) vol. 39 (23), 8060-8066.  
      17-10-2006
    • Screen HRC, Chhaya VH, Greenwald SE, Bader DL, Lee DA and Shelton JC (2006). The influence of swelling and matrix degradation on the microstructural integrity of tendon. Acta Biomater vol. 2 (5), 505-513.  
      01-09-2006
    • BRANFORD O, LEE D, BADER D and GROBBELAAR A (2006). 1.3 The quantitative assessment of flexor tendon adhesion – a novel use of confocal microscopy to evaluate local strain, orientation and organisation. Journal of Hand Surgery (European Volume), Sage Publications vol. 31, 3-3.  
      01-06-2006
    • Knight MM, Bomzon Z, Kimmel E, Sharma AM, Lee DA and Bader DL (2006). Chondrocyte deformation induces mitochondrial distortion and heterogeneous intracellular strain fields. Biomech Model Mechan vol. 5 (2-3), 180-191.  
      01-06-2006
    • Akanji OO, Bader DL and Lee DA (2006). Direct current influences Ca 2+ signalling in chondrocytes. European Cells and Materials vol. 11 (SUPPL.2) 
      01-06-2006
    • Chowdhury TT, Appleby RN, Salter DM, Bader DA and Lee DA (2006). Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes. Biomech Model Mechanobiol vol. 5 (2-3), 192-201.  
      01-06-2006
    • Lee D (2006). Ground plans [13]. Professional Engineering vol. 19 (6) 
      22-03-2006
    • Marsden RL, Lee D, Maibaum M, Yeats C and Orengo CA (2006). Comprehensive genome analysis of 203 genomes provides structural genomics with new insights into protein family space. Nucleic Acids Research, Oxford University Press (Oup) vol. 34 (3), 1066-1080.  
      06-02-2006
    • Marsden RL, Ranea JAG, Sillero A, Redfern O, Yeats C, Maibaum M, Lee D, Addou S, Reeves GA, Dallman TJ and Orengo CA (2006). Exploiting protein structure data to explore the evolution of protein function and biological complexity. Philosophical Transactions of The Royal Society B Biological Sciences, The Royal Society vol. 361 (1467), 425-440.  
      01-02-2006
    • Heywood HK, Bader DL and Lee DA (2006). Rate of oxygen consumption by isolated articular chondrocytes is sensitive to medium glucose concentration. Journal of Cellular Physiology vol. 206 (2), 402-410.  
      01-02-2006
    • Chowdhury TT, Bader DL and Lee DA (2006). Anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated chondrocytes. Biochem Biophys Res Commun vol. 339 (1), 241-247.  
      06-01-2006
    • Bader DL, Lee DA and Knight MM (2006). Chondrocyte Deformation and Mechanotransduction in Cartilage Model Systems(International Workshop 2). The Proceedings of The Bioengineering Conference Annual Meeting of Bed/Jsme, Japan Society of Mechanical Engineers vol. 2005.18, 2-3.  
      01-01-2006
    • Enobakhare B, Bader DL and Lee DA (2006). Concentration and M/G ratio influence the physiochemical and mechanical properties of alginate constructs for tissue engineering. J Appl Biomater Biomech vol. 4 (2), 87-96.  
      01-01-2006
    • Chowdhury TT, Bader DL and Lee DA (2006). Dynamic compression counteracts IL-1beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs. Biorheology vol. 43 (3,4), 413-429.  
      01-01-2006
    • Lee DA (2006). Government: US law ensures funding for protein hydrogel development. Biomedical Materials (DEC.) 
      01-01-2006
    • Lee DA and Gridley A (2006). Industry news: CryoLife, BioForm sign glue deal. Biomedical Materials (DEC.), 7-8.  
      01-01-2006

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