Prof David Lee
BSc (Hons), MA, PhD
All Publications
Page 2 of 5
2011
- Stem cell mechanobiology.
Lee DA, Knight MM, Campbell JJ, Bader DL
J Cell Biochem vol. 112 (1), 1-9.
01-01-2011
2010
- The metabolism of human mesenchymal stem cells during proliferation and differentiation.
Pattappa G, Heywood HK, de Bruijn JD, Lee DA
J Cell Physiol
28-12-2010 - Functional analysis of tenocytes gene expression in tendon fascicles subjected to cyclic tensile strain
Maeda E, Fleischmann C, Mein CA, Shelton JC, Bader DL, Lee DA
Connective Tissue Research vol. 51 (6), 434-444.
01-12-2010 - Electrospray deposited fibronectin retains the ability to promote cell adhesion
Martyn SV, Heywood HK, Rockett P, Paine MD, Wang MJ, Dobson PJ, Sheard SJ, Lee DA et al.
Journal of Biomedical Materials Research Part B Applied Biomaterials, Wiley vol. 96B (1), 110-118.
08-11-2010 - Both superficial and deep zone articular chondrocyte subpopulations exhibit the crabtree effect but have different basal oxygen consumption rates
Heywood HK, Knight MM, Lee DA
Journal of Cellular Physiology vol. 223 (3), 630-639.
01-06-2010 - Giving something back
Lee D
Twist (22), 28-30.
01-06-2010 - A compartment model to evaluate the permeability of gap junctions between tenocytes in tendon fascicles
Ye S, Maeda E, Knight M, Lee D, Bader D, Wang W
Faseb Journal vol. 24
01-01-2010 - Low oxygen reduces the modulation to an oxidative phenotype in monolayer-expanded chondrocytes.
Heywood HK, Lee DA
J Cell Physiol vol. 222 (1), 248-253.
01-01-2010
2009
- Effect of intermittent cyclic tensile strain on collagen synthesis by tenocytes in isolated fascicles
Maeda E, Shelton JC, Bader DL, Lee DA
Journal of Biomechanical Science and Engineering vol. 4 (4), 510-517.
01-12-2009 - GeMMA: functional subfamily classification within superfamilies of predicted protein structural domains
Lee DA, Rentzsch R, Orengo C
Nucleic Acids Research, Oxford University Press (Oup) vol. 38 (3), 720-737.
18-11-2009 - The effect of oxygen tension on the proliferation and differentiation of human mesenchymal stem cells
Pattappa G, Jegard NC, Lee DA, de Bruijn JD
European Cells and Materials vol. 18 (SUPPL. 1)
01-08-2009 - Osteogenic differentiation of human mesenchymal stem cells within a perfused bioreactor system
Campbell JJ, Maeda E, Ye SJ, Wang W, Lee DA
European Cells and Materials vol. 18 (SUPPL. 2)
01-07-2009 - The influence of oxygen tension on the colony formation and proliferation of human mesenchymal stem cells
Pattappa G, Jegard NC, de Bruijn JD, Lee DA
European Cells and Materials vol. 18 (SUPPL. 2)
01-07-2009 - Differential regulation of gene expression in isolated tendon fascicles exposed to cyclic tensile strain in vitro
Maeda E, Shelton JC, Bader DL, Lee DA
Journal of Applied Physiology vol. 106 (2), 506-512.
01-02-2009 - Cell-generated forces influence the viability, metabolism and mechanical properties of fibroblast-seeded collagen gel constructs.
Berry CC, Shelton JC, Lee DA
J Tissue Eng Regen Med vol. 3 (1), 43-53.
01-01-2009 - The development of a bioreactor to perfuse radially-confined hydrogel constructs: design and characterization of mass transport properties.
Eniwumide JO, Lee DA, Bader DL
Biorheology vol. 46 (5), 417-437.
01-01-2009
2008
- Metabolic characteristics of human mesenchymal stem cells expanded under normoxic conditions
Pattappa G, A. Lee D, De Bruijn JD
8th World Biomaterials Congress 2008 vol. 1
01-12-2008 - Phenotypic analysis of Arabidopsis mutants: heavy metal stress.
Lee D, Schroeder J
Cold Spring Harbor Protocols, Cold Spring Harbor Laboratory vol. 2008 (9)
01-09-2008 - Monolayer expansion induces an oxidative metabolism and ROS in chondrocytes.
Heywood HK, Lee DA
Biochem Biophys Res Commun vol. 373 (2), 224-229.
22-08-2008 - Collagen synthesis by tenocytes in fascicles subjected to intermittent cyclic strain
Maeda E, Shelton JC, Bader DL, Lee DA
European Cells and Materials vol. 16 (SUPPL. 3)
01-07-2008 - Signal transduction pathways involving p38 MAPK, JNK, NF kappa B and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1 beta and dynamic compression
Chowdhury TT, Salter DM, Bader DL, Lee DA
Inflamm Res vol. 57 (7), 306-313.
01-07-2008 - The effect of oxygen supply on chondrocyte metabolic phenotype during monolayer culture
Heywood HK, Lee DA
European Cells and Materials vol. 16 (SUPPL. 3)
01-07-2008 - Advantages, Disadvantages, and Uses of Generalized Activity Networks for Schedule Estimation
Hughes D, Whitaker Y, Lee D, Eckhause J
Military Operations Research, Military Operations Research Society vol. 13 (3), 27-40.
01-06-2008 - Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs.
Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Bader DL, Salter DM, Lee DA
Arthritis Res Ther vol. 10 (2)
01-01-2008 - Dynamic compression influences interleukin-1 beta-induced nitric oxide and prostaglandin E-2 release by articular chondrocytes via alterations in iNOS and COX-2 expression
Chowdhury TT, Akanji OO, Salter DM, Bader DL, Lee DA
Biorheology vol. 45 (3-4), 257-274.
01-01-2008 - Mechanical loading modulates intracellular calcium signaling in human mesenchymal stem cells
Campbell JJ, Bader DL, Lee DA
J Appl Biomater Biom vol. 6 (1), 9-15.
01-01-2008 - Surgeons carry out first implant of pulmonary human heart valve
Lee DA
Biomedical Materials (MAY)
01-01-2008
2007
- 52 REAL-TIME PCR USING MOLECULAR BEACONS TO DETECT INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS SUBJECTED TO IL-1β AND DYNAMIC COMPRESSION
Chowdhury TT, Akanji OO, Arghandawi S, Salter DM, Bader DL, Lee DA
Osteoarthritis and Cartilage, Elsevier vol. 15, c42-c43.
01-12-2007 - Predicting protein function from sequence and structure
Lee D, Redfern O, Orengo C
Nature Reviews Molecular Cell Biology, Springer Nature vol. 8 (12), 995-1005.
01-12-2007 - Root contact during insertion of miniscrews for orthodontic anchorage increases the failure rate: an animal study
Chen Y-H, Chang H-H, Chen Y-J, Lee D, Chiang H-H, Jane Yao C-C
Clinical Oral Implants Research, Wiley, 07102500154-???.
23-10-2007 - Time dependence of cyclic tensile strain on collagen production in tendon fascicles.
Maeda E, Shelton JC, Bader DL, Lee DA
Biochem Biophys Res Commun vol. 362 (2), 399-404.
19-10-2007 - Industry news: CryoLife signs Irish distribution deal with Proxy Biomedical
Lee DA
Biomedical Materials (NOV.), 6-7.
01-01-2007 - Products: CryoLife wins rights to distribute replacement pericardium
Lee DA, Hall J
Biomedical Materials (MAR.)
01-01-2007 - Products: CryoLife wins US patent for foam wound sealant
Lee DA
Biomedical Materials (JULY)
01-01-2007
2006
- Glucose Concentration and Medium Volume Influences Cell Viability and Glycosaminoglycan Synthesis in Chondrocyte-Seeded Alginate Constructs
Heywood HK, Bader DL, Lee DA
Tissue Engineering, Mary Ann Liebert
20-11-2006 - Self-Assembly of Latex Particles into Proton-Conductive Membranes
Gao J, Yang Y, Lee D, Holdcroft S, Frisken BJ
Macromolecules, American Chemical Society (Acs) vol. 39 (23), 8060-8066.
17-10-2006 - The influence of swelling and matrix degradation on the microstructural integrity of tendon.
Screen HRC, Chhaya VH, Greenwald SE, Bader DL, Lee DA, Shelton JC
Acta Biomater vol. 2 (5), 505-513.
01-09-2006 - 1.3 The quantitative assessment of flexor tendon adhesion – a novel use of confocal microscopy to evaluate local strain, orientation and organisation
BRANFORD O, LEE D, BADER D, GROBBELAAR A
Journal of Hand Surgery (European Volume), Sage Publications vol. 31, 3-3.
01-06-2006 - Chondrocyte deformation induces mitochondrial distortion and heterogeneous intracellular strain fields
Knight MM, Bomzon Z, Kimmel E, Sharma AM, Lee DA, Bader DL
Biomech Model Mechan vol. 5 (2-3), 180-191.
01-06-2006 - Direct current influences Ca 2+ signalling in chondrocytes
Akanji OO, Bader DL, Lee DA
European Cells and Materials vol. 11 (SUPPL.2)
01-06-2006 - Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes.
Chowdhury TT, Appleby RN, Salter DM, Bader DA, Lee DA
Biomech Model Mechanobiol vol. 5 (2-3), 192-201.
01-06-2006 - Ground plans [13]
Lee D
Professional Engineering vol. 19 (6)
22-03-2006 - Comprehensive genome analysis of 203 genomes provides structural genomics with new insights into protein family space
Marsden RL, Lee D, Maibaum M, Yeats C, Orengo CA
Nucleic Acids Research, Oxford University Press (Oup) vol. 34 (3), 1066-1080.
06-02-2006 - Exploiting protein structure data to explore the evolution of protein function and biological complexity
Marsden RL, Ranea JAG, Sillero A, Redfern O, Yeats C, Maibaum M, Lee D, Addou S et al.
Philosophical Transactions of The Royal Society B Biological Sciences, The Royal Society vol. 361 (1467), 425-440.
01-02-2006 - Rate of oxygen consumption by isolated articular chondrocytes is sensitive to medium glucose concentration
Heywood HK, Bader DL, Lee DA
Journal of Cellular Physiology vol. 206 (2), 402-410.
01-02-2006 - Anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated chondrocytes.
Chowdhury TT, Bader DL, Lee DA
Biochem Biophys Res Commun vol. 339 (1), 241-247.
06-01-2006 - Chondrocyte Deformation and Mechanotransduction in Cartilage Model Systems(International Workshop 2)
Bader DL, Lee DA, Knight MM
The Proceedings of The Bioengineering Conference Annual Meeting of Bed/Jsme, Japan Society of Mechanical Engineers vol. 2005.18, 2-3.
01-01-2006 - Concentration and M/G ratio influence the physiochemical and mechanical properties of alginate constructs for tissue engineering.
Enobakhare B, Bader DL, Lee DA
J Appl Biomater Biomech vol. 4 (2), 87-96.
01-01-2006 - Dynamic compression counteracts IL-1beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs.
Chowdhury TT, Bader DL, Lee DA
Biorheology vol. 43 (3,4), 413-429.
01-01-2006 - Gene3D: modelling protein structure, function and evolution
Yeats C, Maibaum M, Marsden R, Dibley M, Lee D, Addou S, Orengo CA
Nucleic Acids Research, Oxford University Press (Oup) vol. 34 (suppl_1), d281-d284.
01-01-2006