Prof David Lee
BSc (Hons), MA, PhD

 

All Publications

Page 2 of 4

2009

  • Effect of intermittent cyclic tensile strain on collagen synthesis by tenocytes in isolated fascicles
    Maeda E, Shelton JC, Bader DL, Lee DA
    Journal of Biomechanical Science and Engineering vol. 4 (4), 510-517.  
    01-12-2009
  • The effect of oxygen tension on the proliferation and differentiation of human mesenchymal stem cells
    Pattappa G, Jegard NC, Lee DA, de Bruijn JD
    European Cells and Materials vol. 18 (SUPPL. 1) 
    01-08-2009
  • Osteogenic differentiation of human mesenchymal stem cells within a perfused bioreactor system
    Campbell JJ, Maeda E, Ye SJ, Wang W, Lee DA
    European Cells and Materials vol. 18 (SUPPL. 2) 
    01-07-2009
  • The influence of oxygen tension on the colony formation and proliferation of human mesenchymal stem cells
    Pattappa G, Jegard NC, de Bruijn JD, Lee DA
    European Cells and Materials vol. 18 (SUPPL. 2) 
    01-07-2009
  • Differential regulation of gene expression in isolated tendon fascicles exposed to cyclic tensile strain in vitro
    Maeda E, Shelton JC, Bader DL, Lee DA
    Journal of Applied Physiology vol. 106 (2), 506-512.  
    01-02-2009
  • Cell-generated forces influence the viability, metabolism and mechanical properties of fibroblast-seeded collagen gel constructs.
    Berry CC, Shelton JC, Lee DA
    J Tissue Eng Regen Med vol. 3 (1), 43-53.  
    01-01-2009
  • The development of a bioreactor to perfuse radially-confined hydrogel constructs: design and characterization of mass transport properties.
    Eniwumide JO, Lee DA, Bader DL
    Biorheology vol. 46 (5), 417-437.  
    01-01-2009

2008

  • Metabolic characteristics of human mesenchymal stem cells expanded under normoxic conditions
    Pattappa G, A. Lee D, De Bruijn JD
    8th World Biomaterials Congress 2008 vol. 1 
    01-12-2008
  • 498 THE OXIDATIVE METABOLISM INDUCED DURING MONOLAYER EXPANSION OF CHONDROCYTES IS PARTIALLY MODULATED BY OXYGEN SUPPLY
    Heywood HK, Lee DA
    Osteoarthritis and Cartilage, Elsevier vol. 16, s214-s215.  
    01-09-2008
  • Phenotypic analysis of Arabidopsis mutants: heavy metal stress.
    Lee D, Schroeder J
    Cold Spring Harbor Protocols, Cold Spring Harbor Laboratory vol. 2008 (9) 
    01-09-2008
  • Monolayer expansion induces an oxidative metabolism and ROS in chondrocytes.
    Heywood HK, Lee DA
    Biochem Biophys Res Commun vol. 373 (2), 224-229.  
    22-08-2008
  • Collagen synthesis by tenocytes in fascicles subjected to intermittent cyclic strain
    Maeda E, Shelton JC, Bader DL, Lee DA
    European Cells and Materials vol. 16 (SUPPL. 3) 
    01-07-2008
  • Signal transduction pathways involving p38 MAPK, JNK, NF kappa B and AP-1 influences the response of chondrocytes cultured in agarose constructs to IL-1 beta and dynamic compression
    Chowdhury TT, Salter DM, Bader DL, Lee DA
    Inflamm Res vol. 57 (7), 306-313.  
    01-07-2008
  • The effect of oxygen supply on chondrocyte metabolic phenotype during monolayer culture
    Heywood HK, Lee DA
    European Cells and Materials vol. 16 (SUPPL. 3) 
    01-07-2008
  • Advantages, Disadvantages, and Uses of Generalized Activity Networks for Schedule Estimation
    Hughes D, Whitaker Y, Lee D, Eckhause J
    Military Operations Research, Military Operations Research Society vol. 13 (3), 27-40.  
    01-06-2008
  • Dynamic compression counteracts IL-1beta induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs.
    Chowdhury TT, Arghandawi S, Brand J, Akanji OO, Bader DL, Salter DM, Lee DA
    Arthritis Res Ther vol. 10 (2) 
    01-01-2008
  • Dynamic compression influences interleukin-1 beta-induced nitric oxide and prostaglandin E-2 release by articular chondrocytes via alterations in iNOS and COX-2 expression
    Chowdhury TT, Akanji OO, Salter DM, Bader DL, Lee DA
    Biorheology vol. 45 (3-4), 257-274.  
    01-01-2008
  • Mechanical loading modulates intracellular calcium signaling in human mesenchymal stem cells
    Campbell JJ, Bader DL, Lee DA
    J Appl Biomater Biom vol. 6 (1), 9-15.  
    01-01-2008
  • Surgeons carry out first implant of pulmonary human heart valve
    Lee DA
    Biomedical Materials (MAY) 
    01-01-2008

2007

  • 52 REAL-TIME PCR USING MOLECULAR BEACONS TO DETECT INOS AND COX-2 EXPRESSION IN CHONDROCYTE/AGAROSE CONSTRUCTS SUBJECTED TO IL-1β AND DYNAMIC COMPRESSION
    Chowdhury TT, Akanji OO, Arghandawi S, Salter DM, Bader DL, Lee DA
    Osteoarthritis and Cartilage, Elsevier vol. 15, c42-c43.  
    01-12-2007
  • Root contact during insertion of miniscrews for orthodontic anchorage increases the failure rate: an animal study
    Chen Y-H, Chang H-H, Chen Y-J, Lee D, Chiang H-H, Jane Yao C-C
    Clinical Oral Implants Research, Wiley, 07102500154-???.  
    23-10-2007
  • Time dependence of cyclic tensile strain on collagen production in tendon fascicles.
    Maeda E, Shelton JC, Bader DL, Lee DA
    Biochem Biophys Res Commun vol. 362 (2), 399-404.  
    19-10-2007
  • Industry news: CryoLife signs Irish distribution deal with Proxy Biomedical
    Lee DA
    Biomedical Materials (NOV.), 6-7.  
    01-01-2007
  • Products: CryoLife wins rights to distribute replacement pericardium
    Lee DA, Hall J
    Biomedical Materials (MAR.) 
    01-01-2007
  • Products: CryoLife wins US patent for foam wound sealant
    Lee DA
    Biomedical Materials (JULY) 
    01-01-2007

2006

  • Glucose Concentration and Medium Volume Influences Cell Viability and Glycosaminoglycan Synthesis in Chondrocyte-Seeded Alginate Constructs
    Heywood HK, Bader DL, Lee DA
    Tissue Engineering, Sage Publications 
    20-11-2006
  • Un facteur de croissance durant la période de culture pourrait normaliser les capacités de synthèse (matrice et collagène) des chondrocytes autologues transplantés
    Goldberg AJ, Lee DA, Bader DL, Bentley G
    Revue De Chirurgie OrthopéDique Et Traumatologique, Elsevier vol. 92 (7) 
    01-11-2006
  • The influence of swelling and matrix degradation on the microstructural integrity of tendon.
    Screen HRC, Chhaya VH, Greenwald SE, Bader DL, Lee DA, Shelton JC
    Acta Biomater vol. 2 (5), 505-513.  
    01-09-2006
  • 1.3 The quantitative assessment of flexor tendon adhesion – a novel use of confocal microscopy to evaluate local strain, orientation and organisation
    BRANFORD O, LEE D, BADER D, GROBBELAAR A
    Journal of Hand Surgery (European Volume), Sage Publications vol. 31, 3-3.  
    01-06-2006
  • Chondrocyte deformation induces mitochondrial distortion and heterogeneous intracellular strain fields
    Knight MM, Bomzon Z, Kimmel E, Sharma AM, Lee DA, Bader DL
    Biomech Model Mechan vol. 5 (2-3), 180-191.  
    01-06-2006
  • Direct current influences Ca 2+ signalling in chondrocytes
    Akanji OO, Bader DL, Lee DA
    European Cells and Materials vol. 11 (SUPPL.2) 
    01-06-2006
  • Integrin-mediated mechanotransduction in IL-1 beta stimulated chondrocytes.
    Chowdhury TT, Appleby RN, Salter DM, Bader DA, Lee DA
    Biomech Model Mechanobiol vol. 5 (2-3), 192-201.  
    01-06-2006
  • Ground plans [13]
    Lee D
    Professional Engineering vol. 19 (6) 
    22-03-2006
  • Rate of oxygen consumption by isolated articular chondrocytes is sensitive to medium glucose concentration
    Heywood HK, Bader DL, Lee DA
    Journal of Cellular Physiology vol. 206 (2), 402-410.  
    01-02-2006
  • Anti-inflammatory effects of IL-4 and dynamic compression in IL-1beta stimulated chondrocytes.
    Chowdhury TT, Bader DL, Lee DA
    Biochem Biophys Res Commun vol. 339 (1), 241-247.  
    06-01-2006
  • Chondrocyte Deformation and Mechanotransduction in Cartilage Model Systems(International Workshop 2)
    Bader DL, Lee DA, Knight MM
    The Proceedings of The Bioengineering Conference Annual Meeting of Bed/Jsme, Japan Society of Mechanical Engineers vol. 2005.18, 2-3.  
    01-01-2006
  • Concentration and M/G ratio influence the physiochemical and mechanical properties of alginate constructs for tissue engineering.
    Enobakhare B, Bader DL, Lee DA
    J Appl Biomater Biomech vol. 4 (2), 87-96.  
    01-01-2006
  • Dynamic compression counteracts IL-1beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs.
    Chowdhury TT, Bader DL, Lee DA
    Biorheology vol. 43 (3,4), 413-429.  
    01-01-2006
  • Government: US law ensures funding for protein hydrogel development
    Lee DA
    Biomedical Materials (DEC.) 
    01-01-2006
  • Industry news: CryoLife, BioForm sign glue deal
    Lee DA, Gridley A
    Biomedical Materials (DEC.), 7-8.  
    01-01-2006
  • Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose.
    Knight MM, Toyoda T, Lee DA, Bader DL
    J Biomech vol. 39 (8), 1547-1551.  
    01-01-2006
  • P140 DYNAMIC COMPRESSION COUNTERACTS FIBRONECTIN FRAGMENT INDUCED UPREGULATION OF NITRIC OXIDE
    Chowdhury TT, Raveenthiran SP, Bader DL, Lee DA
    Osteoarthritis and Cartilage, Elsevier vol. 14 
    01-01-2006
  • Products: Spinal implant looks good so far
    Lee DA
    Biomedical Materials (JUNE), 4-5.  
    01-01-2006
  • Spinal implants: CryoLife's spinal disc repair study completes enrolment
    Lee DA
    Biomedical Materials (SEP.), 9-10.  
    01-01-2006

2005

  • Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles.
    Pingguan-Murphy B, Lee DA, Bader DL, Knight MM
    Arch Biochem Biophys vol. 444 (1), 45-51.  
    01-12-2005
  • Cyclic mechanical conditioning of isolated tendon fascicles results in an upregulation of collagen production
    Screen HRC, Bader DL, Shelton JC, Lee DA
    Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 193-194.  
    01-12-2005
  • Dynamic compression counteracts IL-1-induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs
    Chowdhury TT, Bader DL, Lee DA
    Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 251-252.  
    01-12-2005
  • Identification and characterization of deposited fibronectin on biocompatible materials: Comparison of electrospray and wetting methods
    Wang MJ, Heywood HK, Bader DL, Paine MD, Stark JPW, Lee DA
    Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 439-440.  
    01-12-2005
  • Integrin mediated mechanotransduction in IL-1 stimulated bovine chondrocytes cultured in agarose constructs
    Chowdhury TT, Appleby RN, Salter DA, Bader DL, Lee DA
    Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 545-546.  
    01-12-2005
  • Mechanical conditioning of cell-seeded constructs for soft tissue repair - Are optimisation strategies possible?
    Bader DL, Lee DA
    , 165-192.  
    01-12-2005

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