Prof David Lee
BSc (Hons), MA, PhD

 

All Publications

Page 3 of 5

2006

  • Industry news: CryoLife, BioForm sign glue deal
    Lee DA and Gridley A
    Biomedical Materials (DEC.), 7-8.  
    01-01-2006
  • Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose.
    Knight MM, Toyoda T, Lee DA and Bader DL
    J Biomech vol. 39 (8), 1547-1551.  
    01-01-2006
  • P140 DYNAMIC COMPRESSION COUNTERACTS FIBRONECTIN FRAGMENT INDUCED UPREGULATION OF NITRIC OXIDE
    Chowdhury TT, Raveenthiran SP, Bader DL and Lee DA
    Osteoarthritis and Cartilage, Elsevier vol. 14 
    01-01-2006
  • Products: Spinal implant looks good so far
    Lee DA
    Biomedical Materials (JUNE), 4-5.  
    01-01-2006
  • Spinal implants: CryoLife's spinal disc repair study completes enrolment
    Lee DA
    Biomedical Materials (SEP.), 9-10.  
    01-01-2006

2005

  • Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles.
    Pingguan-Murphy B, Lee DA, Bader DL and Knight MM
    Arch Biochem Biophys vol. 444 (1), 45-51.  
    01-12-2005
  • Cyclic mechanical conditioning of isolated tendon fascicles results in an upregulation of collagen production
    Screen HRC, Bader DL, Shelton JC and Lee DA
    Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 193-194.  
    01-12-2005
  • Dynamic compression counteracts IL-1-induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs
    Chowdhury TT, Bader DL and Lee DA
    Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 251-252.  
    01-12-2005
  • Identification and characterization of deposited fibronectin on biocompatible materials: Comparison of electrospray and wetting methods
    Wang MJ, Heywood HK, Bader DL, Paine MD, Stark JPW and Lee DA
    Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 439-440.  
    01-12-2005
  • Integrin mediated mechanotransduction in IL-1 stimulated bovine chondrocytes cultured in agarose constructs
    Chowdhury TT, Appleby RN, Salter DA, Bader DL and Lee DA
    Proceedings of The 2005 Summer Bioengineering Conference vol. 2005, 545-546.  
    01-12-2005
  • Mechanical conditioning of cell-seeded constructs for soft tissue repair - Are optimisation strategies possible?
    Bader DL and Lee DA
    , 165-192.  
    01-12-2005
  • Cyclic tensile strain upregulates collagen synthesis in isolated tendon fascicles.
    Screen HRC, Shelton JC, Bader DL and Lee DA
    Biochem Biophys Res Commun vol. 336 (2), 424-429.  
    21-10-2005
  • Nutrient utilization by bovine articular chondrocytes: a combined experimental and theoretical approach.
    Sengers BG, Heywood HK, Lee DA, Oomens CWJ and Bader DL
    J Biomech Eng vol. 127 (5), 758-766.  
    01-10-2005
  • The influence of noncollagenous matrix components on the micromechanical environment of tendon fascicles.
    Screen HRC, Shelton JC, Chhaya VH, Kayser MV, Bader DL and Lee DA
    Ann Biomed Eng vol. 33 (8), 1090-1099.  
    01-08-2005
  • Dynamic compression counteracts IL-1β induced INOS and COX-2 activity by human chondrocytes cultured in agarose constructs
    Chowdhury TT, Bader DL and Lee DA
    European Cells and Materials vol. 10 (SUPPL.2) 
    01-07-2005
  • Dynamic compression influences the biochemical response of human mesenchymal stem cells cultured in agarose constructs
    Catuogno C, Chowdhury TT, Bader DL and Lee DA
    European Cells and Materials vol. 10 (SUPPL.2) 
    01-07-2005
  • Mechanical conditioning Influences Mesenchymal stem cell chondrogenesis
    Campbell JJ, Lee DA and Bader DL
    European Cells and Materials vol. 10 (SUPPL.2) 
    01-07-2005
  • Perfusion-Enhancement of molecular transport within 3D scaffolds
    Eniwumide JO, Lee DA and Bader DL
    European Cells and Materials vol. 10 (SUPPL.2) 
    01-07-2005
  • Superficial and deep chondrocyte subpopulations both express the crabtree effect but exhibit differences in oxygen consumption rate
    Heywood HK, Bader DL and Lee DA
    European Cells and Materials vol. 10 (SUPPL.2) 
    01-07-2005
  • Self-Assembly of Surface-Charged Latex Nanoparticles: A New Route to the Creation of Continuous Channels for Ion Conduction
    Gao J, Lee D, Yang Y, Holdcroft S and Frisken BJ
    Macromolecules, American Chemical Society (Acs) vol. 38 (14), 5854-5856.  
    15-06-2005
  • British Society for Matrix Biology Autumn Meeting Joint with the UK Tissue & Cell Engineering Society, University of Bristol, UK

    International Journal of Experimental Pathology, Wiley vol. 86 (3), a1-a56.  
    24-05-2005
  • Identification and distribution of protein families in 120 completed genomes using Gene3D
    Lee D, Grant A, Marsden RL and Orengo C
    Proteins Structure Function and Bioinformatics, Wiley vol. 59 (3), 603-615.  
    14-03-2005
  • Autologous chondrocyte implantation. Culture in a TGF-beta-containing medium enhances the re-expression of a chondrocytic phenotype in passaged human chondrocytes in pellet culture.
    Goldberg AJ, Lee DA, Bader DL and Bentley G
    J Bone Joint Surg Br vol. 87 (1), 128-134.  
    01-01-2005
  • Compression-induced damage in a muscle cell model in vitro.
    Wang Y-N, Bouten CVC, Lee DA and Bader DL
    Proc Inst Mech Eng H vol. 219 (1), 1-12.  
    01-01-2005

2004

  • The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis
    Pearl F, Todd A, Sillitoe I, Dibley M, Redfern O, Lewis T, Bennett C, Marsden R, Grant A, Lee D, Akpor A, Maibaum M, Harrison A, Dallman T, Reeves G, Diboun I, Addou S, Lise S, Johnston C, Sillero A, Thornton J and Orengo C
    Nucleic Acids Research, Oxford University Press (Oup) vol. 33 (suppl_1), d247-d251.  
    17-12-2004
  • Delusional discourse: An investigation comparing the spontaneous causal attributions of paranoid and non‐paranoid individuals
    Lee DA, Randall F, Beattie G and Bentall RP
    Psychology and Psychotherapy Theory Research and Practice, Wiley vol. 77 (4), 525-540.  
    01-12-2004
  • Local Strain Measurement within Tendon
    Bader DL, Shelton JC, Lee DA and SCREEN HRC
    Strain vol. 40 (4), 157-163.  
    01-11-2004
  • Crosslinking density influences the morphology of chondrocytes photoencapsulated in PEG hydrogels during the application of compressive strain.
    Bryant SJ, Anseth KS, Lee DA and Bader DL
    J Orthop Res vol. 22 (5), 1143-1149.  
    01-09-2004
  • Integrin-mediated mechanotransduction processes in TGFbeta-stimulated monolayer-expanded chondrocytes.
    Chowdhury TT, Salter DM, Bader DL and Lee DA
    Biochem Biophys Res Commun vol. 318 (4), 873-881.  
    11-06-2004
  • Debt crisis looms [10]
    Lee D
    Professional Engineering vol. 17 (8) 
    28-04-2004
  • Activin Receptor-like Kinase-7 Induces Apoptosis through Activation of MAPKs in a Smad3-dependent Mechanism in Hepatoma Cells*
    Kim B-C, van Gelder H, Kim TA, Lee H-J, Baik KG, Chun HH, Lee DA, Choi KS and Kim S-J
    Journal of Biological Chemistry, Elsevier vol. 279 (27), 28458-28465.  
    23-04-2004
  • Crosslinking density influences chondrocyte metabolism in dynamically loaded photocrosslinked poly(ethylene glycol) hydrogels.
    Bryant SJ, Chowdhury TT, Lee DA, Bader DL and Anseth KS
    Ann Biomed Eng vol. 32 (3), 407-417.  
    01-03-2004
  • An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties.
    Screen HRC, Lee DA, Bader DL and Shelton JC
    Proc Inst Mech Eng H vol. 218 (2), 109-119.  
    01-01-2004
  • Cellular utilization determines viability and matrix distribution profiles in chondrocyte-seeded alginate constructs.
    Heywood HK, Sembi PK, Lee DA and Bader DL
    Tissue Eng vol. 10 (9-10), 1467-1479.  
    01-01-2004
  • Extracellular matrix influences the response of chondrocytes to dynamic compression
    LEE DA, van Osch G, Verhaar JAN, Mandl EW, van der Linden JC, van der Breevaart Bravenboer J and Weinans H
    Trans. Orthop.Rev. Soc vol. 29, 839-839.  
    01-01-2004
  • EyeSite: a semi‐automated database of protein families in the eye
    Lee DA, Fefeu S, Edo-Ukeh AA, Orengo CA and Slingsby C
    Nucleic Acids Research, Oxford University Press (Oup) vol. 32 (suppl_1), d148-d152.  
    01-01-2004
  • Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage
    Bader DL, KNIGHT MM, Bentley G, Kayser M and Holloway I
    Osteoarthritis Cartilage vol. 12 (1), 17-24.  
    01-01-2004
  • Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage.
    Holloway I, Kayser M, Lee DA, Bader DL, Bentley G and Knight MM
    Osteoarthritis Cartilage vol. 12 (1), 17-24.  
    01-01-2004
  • Mechanical loading of chondrocytes embedded in 3D constructs: in vitro methods for assessment of morphological and metabolic response to compressive strain.
    Lee DA and Knight MM
    Methods Mol Med vol. 100, 307-324.  
    01-01-2004
  • Passage in monolayer influences the response of chondrocytes to dynamic compression.
    Wiseman M, Bader DL, Reisler T and Lee DA
    Biorheology vol. 41 (3-4), 283-298.  
    01-01-2004
  • Progress towards mapping the universe of protein folds
    Grant A, Lee D and Orengo C
    Genome Biology, Springer Nature vol. 5 (5) 
    01-01-2004

2003

  • Dynamic compression counteracts IL-1 beta-induced release of nitric oxide and PGE2 by superficial zone chondrocytes cultured in agarose constructs.
    Chowdhury TT, Bader DL and Lee DA
    Osteoarthritis Cartilage vol. 11 (9), 688-696.  
    01-09-2003
  • Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression.
    Chowdhury TT, Bader DL, Shelton JC and Lee DA
    Arch Biochem Biophys vol. 417 (1), 105-111.  
    01-09-2003
  • Influence of external uniaxial cyclic strain on oriented fibroblast-seeded collagen gels.
    Berry CC, Shelton JC, Bader DL and Lee DA
    Tissue Eng vol. 9 (4), 613-624.  
    01-08-2003
  • Dynamic compressive strain inhibits nitric oxide synthesis by equine chondrocytes isolated from different areas of the cartilage surface.
    Wiseman M, Henson F, Lee DA and Bader DL
    Equine Vet J vol. 35 (5), 451-456.  
    01-07-2003
  • A structural perspective on genome evolution
    Lee D, Grant A, Buchan D and Orengo C
    Current Opinion in Structural Biology, Elsevier vol. 13 (3), 359-369.  
    01-06-2003
  • Live cell imaging using confocal microscopy induces intracellular calcium transients and cell death.
    Knight MM, Roberts SR, Lee DA and Bader DL
    Am J Physiol Cell Physiol vol. 284 (4), C1083-C1089.  
    01-04-2003
  • Expansion of chondrocytes for tissue engineering in alginate beads enhances chondrocytic phenotype compared to conventional monolayer techniques.
    Lee DA, Reisler T and Bader DL
    Acta Orthop Scand vol. 74 (1), 6-15.  
    01-02-2003
  • alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta-stimulated human chondrocyte / agarose constructs and subjected to dynamic compression.
    Chowdhury TT, LEE DA, Salter DM, Shelton JC and Bader DL
    Osteoarthritis Cartilage vol. 11 (Suppl 1), S2-S3.  
    01-01-2003
  • Control of mechanotrasduction processes in dynamically stimulated human and bovine chondrocytes cultured in agarose constructs.
    Chowdhury TT, Shelton JC, Bader DL and LEE DA
    Internat. J. Artificial Organs vol. 26 (9), 858-858.  
    01-01-2003

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