Prof Rob Krams
MD, PhD
All Publications
Page 3 of 5
2008
- REGULATION OF ARGINASE IN RESPONSE SHEAR STRESS: NEW POTENTIAL THERAPEUTIC TARGET ATHEROSCLEROSIS?
da Silva RF, Olivon VC, Segers D, de Crom R, Krams R and Stergiopulos N
Journal of Biomechanics, Elsevier vol. 41
01-07-2008 - A numerical model to predict abdominal aortic aneurysm expansion based on local wall stress and stiffness
Helderman F, Manoch IJ, Breeuwer M, Kose U, Schouten O, van Sambeek MRM, Poldermans D, Pattynama PTM, Wisselink W, van der Steen AFW and Krams R
Medical & Biological Engineering & Computing, Springer Nature vol. 46 (11)
03-06-2008 - Atherosclerosis: cell biology and lipoproteins – new developments in imaging of inflammation of the vulnerable plaque
Foin N, Evans P and Krams R
Current Opinion in Lipidology, Wolters Kluwer vol. 19 (1), 98-100.
01-02-2008 - P1.57 Modulation of Arginase in Response to Wall Shear Stress
da Silva RF, Olivon VC, Segers D, de Crom R, Krams R and Stergiopulos N
Artery Research, Springer Nature vol. 2 (3), 105-106.
01-01-2008
2007
- Rapamycin modulates the eNOS vs. shear stress relationship
Cheng C, Tempel D, Oostlander A, Helderman F, Gijsen F, Wentzel J, van Haperen R, Haitsma DB, Serruys PW, van der Steen AFW, de Crom R and Krams R
Cardiovascular Research, Oxford University Press (Oup) vol. 78 (1), 123-129.
13-12-2007 - Abstract 879: The Chemokine CXCL10 Is Involved In The Development Of Atherosclerotic Plaque Vulnerability
Segers D, de Crom R, Leenen P, Pasterkamp G and Krams R
Circulation, Wolters Kluwer vol. 116 (suppl_16)
16-10-2007 - Effect of shear stress on vascular inflammation and plaque development
Helderman F, Segers D, de Crom R, Hierck BP, Poelmann RE, Evans PC and Krams R
Current Opinion in Lipidology, Wolters Kluwer vol. 18 (5), 527-533.
01-10-2007 - Subharmonic Contrast Intravascular Ultrasound for Vasa Vasorum Imaging
Goertz DE, Frijlink ME, Tempel D, Bhagwandas V, Gisolf A, Krams R, de Jong N and van der Steen AFW
Ultrasound in Medicine & Biology, Elsevier vol. 33 (12), 1859-1872.
02-08-2007 - Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis
Van der Heiden K, Hierck BP, Krams R, de Crom R, Cheng C, Baiker M, Pourquie MJBM, Alkemade FE, DeRuiter MC, Groot ACG-D and Poelmann RE
Atherosclerosis, Elsevier vol. 196 (2), 542-550.
13-07-2007 - Coronary flow reserve in hypertrophic cardiomyopathy: relation with microvascular dysfunction and pathophysiological characteristics
Kofflard MJ, Michels M, Krams R, Kliffen M, Geleijnse ML, Cate FJT and Serruys PW
Netherlands Heart Journal, Springer Nature vol. 15 (6), 209-215.
01-06-2007 - Assessment of Unstable Atherosclerosis in Mice
Jackson CL, Bennett MR, Biessen EAL, Johnson JL and Krams R
Arteriosclerosis Thrombosis and Vascular Biology, Wolters Kluwer vol. 27 (4), 714-720.
01-03-2007 - Shear stress–induced changes in atherosclerotic plaque composition are modulated by chemokines
Cheng C, Tempel D, van Haperen R, de Boer HC, Segers D, Huisman M, van Zonneveld AJ, Leenen PJM, van der Steen A, Serruys PW, de Crom R and Krams R
Journal of Clinical Investigation, American Society For Clinical Investigation vol. 117 (3), 616-626.
15-02-2007 - Vasa vasorum and molecular imaging of atherosclerotic plaques using nonlinear contrast intravascular ultrasound
Goertz DE, Frijlink ME, Krams R, de Jong N and van der Steen AFW
Netherlands Heart Journal, Springer Nature vol. 15 (2), 77-80.
01-02-2007 - Gelatinolytic Activity in Atherosclerotic Plaques Is Highly Localized and Is Associated With Both Macrophages and Smooth Muscle Cells In Vivo
Segers D, Helderman F, Cheng C, van Damme LCA, Tempel D, Boersma E, Serruys PW, de Crom R, van der Steen AFW, Holvoet P and Krams R
Circulation, Wolters Kluwer vol. 115 (5), 609-616.
22-01-2007 - Modulation of arginases by different patterns of shear stress: new signaling pathway in atherogenesis?
Da Silva RF, Gambillara V, Krams R and Stergiopulos N
Computer Methods in Biomechanics & Biomedical Engineering, Taylor & Francis vol. 10 (sup1), 77-78.
01-01-2007 - P.096 Role of Arginase Pathway in Response to Shear Stress: New Potential Therapeutic Targets for Atherosclerosis?
da Silva RF, Gambillara V, Cheng C, Segers D, de Crom R, Krams R and Stergiopulos N
Artery Research, Springer Nature vol. 1 (2), 74-75.
01-01-2007
2006
- Large variations in absolute wall shear stress levels within one species and between species
Cheng C, Helderman F, Tempel D, Segers D, Hierck B, Poelmann R, van Tol A, Duncker DJ, Robbers-Visser D, Ursem NTC, van Haperen R, Wentzel JJ, Gijsen F, van der Steen AFW, de Crom R and Krams R
Atherosclerosis, Elsevier vol. 195 (2), 225-235.
12-12-2006 - Response to Letter Regarding Article, “Atherosclerotic Lesion Size and Vulnerability Are Determined by Patterns of Fluid Shear Stress”
Cheng C, Tempel D, van der Baan A, Krams R, Daemen MJAP, van Haperen R, Grosveld F and de Crom R
Circulation, Wolters Kluwer vol. 114 (22)
28-11-2006 - Harmonic intravascular ultrasound imaging with a dual-frequency catheter
Frijlink ME, Goertz DE, Vos HJ, Tesselaar E, Blacquière G, Gisolf A, Krams R and van der Steen AFW
Ultrasound in Medicine & Biology, Elsevier vol. 32 (11), 1649-1654.
01-11-2006 - Intravascular ultrasound tissue harmonic imaging in vivo
Frijlink ME, Goertz DE, van Damme LCA, Krams R and van der Steen AFW
IEEE Transactions On Ultrasonics Ferroelectrics and Frequency Control, Institute of Electrical and Electronics Engineers (IEEE) vol. 53 (10), 1844-1852.
01-10-2006 - Angiotensin II induces severe intra-plaque hemorrhages in lesions with a vulnerable plaque phenotype
Cheng C, Tempel D, van Damme L, van Haperen R, Krams R and de Crom R
Vascular Pharmacology, Elsevier vol. 45 (3), e91-e92.
01-09-2006 - Patterns of fluid shear stress determine atherosclerotic lesion size and vulnerability
Cheng C, Tempel D, van Damme L, van Haperen R, Krams R and de Crom R
Vascular Pharmacology, Elsevier vol. 45 (3)
01-09-2006 - Contrast Harmonic Intravascular Ultrasound
Goertz DE, Frijlink ME, Tempel D, van Damme LCA, Krams R, Schaar JA, Cate FJT, Serruys PW, de Jong N and van der Steen AFW
Investigative Radiology, Wolters Kluwer vol. 41 (8), 631-638.
01-08-2006 - Shear stress is associated with markers of plaque vulnerability and MMP-9 activity.
Krams R, Cheng C, Helderman F, Verheye S, van Damme LCA, Mousavi Gourabi B, Tempel D, Segers D, de Feyter P, Pasterkamp G, De Klein D, de Crom R, van der Steen AFW and Serruys PW
Eurointervention vol. 2 (2), 250-256.
01-08-2006 - Atherosclerotic Lesion Size and Vulnerability Are Determined by Patterns of Fluid Shear Stress
Cheng C, Tempel D, van Haperen R, van der Baan A, Grosveld F, Daemen MJAP, Krams R and de Crom R
Circulation, Wolters Kluwer vol. 113 (23), 2744-2753.
05-06-2006 - Norepinephrine-induced vasoconstriction results in decreased blood volume in dialysis patients
Nette RW, Ie EHY, Vletter WB, Krams R, Weimar W and Zietse R
Nephrology Dialysis Transplantation, Oxford University Press (Oup) vol. 21 (5), 1305-1311.
31-01-2006 - Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress
Cheng C, Tempel D, van Haperen R, van der Baan A, Grosveld F, Daemen MJAP, Krams R and de Crom R
Circulation vol. 113 (23), 2744-2753.
01-01-2006 - Numerical model for predicting dilatation of an Abdominal Aortic Aneurysm (AAA)
Helderman F, Schouten O, Manoch I, Buffart H, van der Steen AFW and Krams R
Journal of Biomechanics, Elsevier vol. 39
01-01-2006 - Shear stress and atherosclerosis
Krams R
Journal of Biomechanics, Elsevier vol. 39
01-01-2006
2005
- Shear Stress Biology of the Endothelium
Davies PF, Spaan JA and Krams R
Annals of Biomedical Engineering, Springer Nature vol. 33 (12), 1714-1718.
01-12-2005 - In vivo temperature heterogeneity is associated with plaque regions of increased MMP-9 activity
Krams R, Verheye S, van Damme LCA, Tempel D, Mousavi Gourabi B, Boersma E, Kockx MM, Knaapen MWM, Strijder C, van Langenhove G, Pasterkamp G, van der Steen AFW and Serruys PW
European Heart Journal, Oxford University Press (Oup) vol. 26 (20), 2200-2205.
05-09-2005 - Myocardial contractility does not determine the haemodynamic response during dialysis
Ie EHY, Krams R, Vletter WB, Nette RW, Weimar W and Zietse R
Nephrology Dialysis Transplantation, Oxford University Press (Oup) vol. 20 (11), 2465-2471.
23-08-2005 - Shear stress affects the intracellular distribution of eNOS: direct demonstration by a novel in vivo technique
Cheng C, van Haperen R, de Waard M, van Damme LCA, Tempel D, Hanemaaijer L, van Cappellen GWA, Bos J, Slager CJ, Duncker DJ, van der Steen AFW, de Crom R and Krams R
Blood, American Society of Hematology vol. 106 (12), 3691-3698.
16-08-2005 - Monocyte Adhesion in Atherosclerosis: A Biomechanical Approach
Segers D, Cheng C, Crom RD, Kirschbaum SWM, Oostlander AE, Helderman F, Wamel AV, Slager CJ, Serruys PW, Steen AFWVD and Krams R
Vascular Disease Prevention, Bentham Science Publishers vol. 2 (3), 227-235.
01-07-2005 - Effect of vessel curvature on Doppler derived velocity profiles and fluid flow
Krams R, Bambi G, Guidi F, Helderman F, van der Steen AFW and Tortoli P
Ultrasound in Medicine & Biology, Elsevier vol. 31 (5), 663-671.
01-05-2005 - Letter Regarding Article by Korshunov and Berk, “Strain-Dependent Vascular Remodeling: The ‘Glagov Phenomenon’ Is Genetically Determined”
Wentzel JJ, Krams R and Slager CJ
Circulation, Wolters Kluwer vol. 111 (9), e119-e119.
21-02-2005 - Three-Dimensional Palpography of Human Coronary Arteries
Schaar* JA, de Korte* CL, Mastik F, van Damme LCA, Krams R, Serruys PW and van der Steen AFW
Herz, Springer Nature vol. 30 (2), 125-133.
01-02-2005
2004
- Geometry guided data averaging enables the interpretation of shear stress related plaque development in human coronary arteries
Wentzel JJ, Gijsen FJH, Schuurbiers JCH, Krams R, Serruys PW, De Feyter PJ and Slager CJ
Journal of Biomechanics, Elsevier vol. 38 (7), 1551-1555.
23-12-2004 - Diastolic coronary vascular reserve: a new index to detect changes in the coronary microcirculation in hypertrophic cardiomyopathy
Krams R, Cate FJT, Carlier SG, van der Steen AFW and Serruys PW
Journal of The American College of Cardiology, Elsevier vol. 43 (4), 670-677.
01-02-2004 - Intravascular thermography: Immediate functional and morphological vascular findings
Verheye S, De Meyer GRY, Krams R, Kockx MM, Van Damme LCA, Mousavi Gourabi B, Knaapen MWM, Van Langenhove G and Serruys PW
European Heart Journal, Oxford University Press (Oup) vol. 25 (2), 158-165.
01-01-2004 - The role of shear stress in atherosclerosis
Cheng C, de Crom R, van Haperen R, Helderman F, Gourabi BM, van Damme LCA, Kirschbaum SW, Slager CJ, van der Steen AFW and Krams R
Cell Biochemistry and Biophysics, Springer Nature vol. 41 (2), 279-294.
01-01-2004
2003
- Functional Expression of Endothelial Nitric Oxide Synthase Fused to Green Fluorescent Protein in Transgenic Mice
van Haperen R, Cheng C, Mees BME, van Deel E, de Waard M, van Damme LCA, van Gent T, van Aken T, Krams R, Duncker DJ and de Crom R
American Journal of Pathology, Elsevier vol. 163 (4), 1677-1686.
01-10-2003 - The effect of reduced blood-flow on the coronary wall temperature
Diamantopoulos L, Liu X, De Scheerder I, Krams R, Li S, Van Cleemput J, Desmet W and Serruys PW
European Heart Journal, Oxford University Press (Oup) vol. 24 (19), 1788-1795.
01-10-2003 - Imaging of coronary atherosclerosis and identification of the vulnerable plaque.
de Feyter PJ, Serruys PW, Nieman K, Mollet N, Cademartiri F, van Geuns RJ, Slager C, van der Steen AFW, Krams R, Schaar JA, Wielopolski P, Pattynama PMT, Arampatzis A, van der Lugt A, Regar E, Ligthart J and Smits P
Netherlands Heart Journal vol. 11 (9), 347-358.
01-09-2003 - Extension of Increased Atherosclerotic Wall Thickness Into High Shear Stress Regions Is Associated With Loss of Compensatory Remodeling
Wentzel JJ, Janssen E, Vos J, Schuurbiers JCH, Krams R, Serruys PW, de Feyter PJ and Slager CJ
Circulation, Wolters Kluwer vol. 108 (1), 17-23.
23-06-2003 - Augmentation of Wall Shear Stress Inhibits Neointimal Hyperplasia After Stent Implantation
Carlier SG, van Damme LCA, Blommerde CP, Wentzel JJ, van Langehove G, Verheye S, Kockx MM, Knaapen MWM, Cheng C, Gijsen F, Duncker DJ, Stergiopulos N, Slager CJ, Serruys PW and Krams R
Circulation, Wolters Kluwer vol. 107 (21), 2741-2746.
12-05-2003 - Shear stress, vascular remodeling and neointimal formation
Wentzel JJ, Gijsen FJH, Stergiopulos N, Serruys PW, Slager CJ and Krams R
Journal of Biomechanics, Elsevier vol. 36 (5), 681-688.
01-05-2003 - Inflammation and Atherosclerosis:
KRAMS R, SEGERS D, GOURABI BM, MAAT W, CHENG C, VAN PELT C, VAN DAMME LCA, DE FEYTER P, VAN DER STEEN T, DE KORTE CL and SERRUYS PW
Journal of Interventional Cardiology, Wiley vol. 16 (2), 107-113.
01-04-2003
2002
- High shear stress after successful balloon angioplasty is associated with restenosis and target lesion revascularization
Thury A, van Langenhove G, Carlier SG, Albertal M, Kozuma K, Regar E, Sianos G, Wentzel JJ, Krams R, Slager CJ, Piek JJ, Serruys PW and Investigators D
American Heart Journal, Elsevier vol. 144 (1), 136-143.
01-07-2002 - Focal In-Stent Restenosis Near Step-Up
Thury A, Wentzel JJ, Vinke RVH, Gijsen FJH, Schuurbiers JCH, Krams R, de Feyter PJ, Serruys PW and Slager CJ
Circulation, Wolters Kluwer vol. 105 (23), 185e-1187.
11-06-2002