Prof Rob Krams
MD, PhD

 

All Publications

    2022

    • Krams IA, Mennerat A, Krama T, Krams R, Joers P, Elferts D, Luoto S, Rantala MJ and Eliassen S (2022). "Extra-pair paternity explains cooperation in a bird species." Proceedings of The National Academy of Sciences of The United States of America vol. 119 (5)
      01-02-2022

    2021

    • Herault S, Naser J, Carassiti D, Chooi KY, Nikolopoulou R, Font ML, Patel M, Pedrigi R and Krams R (2021). "Mechanosensitive pathways are regulated by mechanosensitive miRNA clusters in endothelial cells." Springer (Part of Springer Nature)  Biophysical Reviews vol. 13 (5), 787-796.
      23-10-2021
    • Naser J, Fogell N, Patel M, Yang P, Krams R, Wentzel JJ, Aben JP and De Silva R (2021). "Moving shear stress towards the clinic: preclinical comparison of optical coherence tomography-based versus angiography-based time-averaged wall shear stress estimations." European Heart Journal vol. 42 (Supplement_1)
      12-10-2021
    • (2021). "Correction: BS18 Profiling endothelial gene expression in coronary atherosclerotic plaques in a human-like D374Y-PCSK9 hyperlipidaemic porcine model." Heart vol. 107 (19), e10-e10.
      14-09-2021
    • Patel M, Savvopoulos F, Berggren CC, Aslanidou L, Timmins LH, de Silva R, Pedrigi RM and Krams R (2021). "Considerations for analysis of endothelial shear stress and strain in FSI models of atherosclerosis." Elsevier  Journal of Biomechanics vol. 128
      28-08-2021

    2020

    • POST AL, CERNOHORSKY P, PEDRIGI RM, STREEKSTRA GJ, D'HOOGHE JNS, ANNEMA JT, STRACKEE SD, KRAMS R, VAN LEEUWEN TG, DE BRUIN DLM and FABER DJ (2020). "3D co-registration algorithm for catheter-based optical coherence tomography." Osa Continuum vol. 3 (10), 2707-2721.
      15-10-2020
    • Bourantas CV, Zanchin T, Torii R, Serruys PW, Karagiannis A, Ramasamy A, Safi H, Coskun AU, Koning G, Onuma Y, Zanchin C, Krams R, Mathur A, Baumbach A, Mintz G, Windecker S, Lansky A, Maehara A, Stone PH, Raber L and Stone GW (2020). "Shear Stress Estimated by Quantitative Coronary Angiography Predicts Plaques Prone to Progress and Cause Events." Jacc: Cardiovascular Imaging vol. 13 (10), 2206-2219.
      01-10-2020
    • Evans RJ, Lavin B, Phinikaridou A, Chooi KY, Mohri Z, Wong E, Boyle JJ, Krams R, Botnar R and Long NJ (2020). "Targeted molecular iron oxide contrast agents for imaging atherosclerotic plaque." Nanotheranostics vol. 4 (4), 184-194.
      01-01-2020

    2019

    • Gijsen F, Katagiri Y, Barlis P, Bourantas C, Collet C, Coskun U, Daemen J, Dijkstra J, Edelman E, Evans P, van der Heiden K, Hose R, Koo B-K, Krams R, Marsden A, Migliavacca F, Onuma Y, Ooi A, Poon E, Samady H, Stone P, Takahashi K, Tang D, Thondapu V, Tenekecioglu E, Timmins L, Torii R, Wentzel J and Serruys P (2019). "Expert recommendations on the assessment of wall shear stress in human coronary arteries: existing methodologies, technical considerations, and clinical applications." Oxford University Press (Oup)  European Heart Journal
      30-09-2019
    • Baumbach A (2019). "Reliable in Vivo Intravascular Imaging Plaque Characterisation: A Challenge Unmet." Elsevier  American Heart Journal
      23-07-2019
    • Mohri Z, Del Rio Hernandez A and Krams R (2019). "The emerging role of YAP/TAZ in mechanotransduction." J Thorac Dis vol. 9 (5), E507-E509.
      01-05-2019
    • Baeriswyl DC, Prionisti I, Peach T, Tsolkas G, Chooi KY, Vardakis J, Morel S, Diagbouga MR, Bijlenga P, Cuhlmann S, Evans P, Kwak BR, Ventikos Y and Krams R (2019). "Disturbed flow induces a sustained, stochastic NF-κB activation which may support intracranial aneurysm growth in vivo." Sci Rep vol. 9 (1), 4738-4738.
      18-03-2019
    • Poulsen CB, Pedrigi RM, Pareek N, Kilic ID, Holm NR, Bentzon JF, Bøtker HE, Falk E, Krams R and de Silva R (2019). "Plaque burden influences accurate classification of fibrous cap atheroma by in vivo optical coherence tomography in a porcine model of advanced coronary atherosclerosis." Eurointervention vol. 14 (10), 1129-1135.
      20-02-2019

    2018

    • Abuammah A, Maimari N, Towhidi L, Frueh J, Chooi KY, Warboys C and Krams R (2018). "New developments in mechanotransduction: Cross talk of the Wnt, TGF-β and Notch signalling pathways in reaction to shear stress." Current Opinion in Biomedical Engineering vol. 5, 96-104.
      01-03-2018

    2017

    • Seneviratne AN, Edsfeldt A, Cole JE, Kassiteridi C, Swart M, Park I, Green P, Khoyratty T, Saliba D, Goddard ME, Sansom SN, Goncalves I, Krams R, Udalova IA and Monaco C (2017). "Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis." American Heart Association, Inc  Circulation vol. 136 (12), 1140-1154.
      11-07-2017
    • Denis J-F, Scheckenbach KEL, Pfenniger A, Meens MJ, Krams R, Miquerol L, Taffet S, Chanson M, Delmar M and Kwak BR (2017). "Connexin40 controls endothelial activation by dampening NFκB activation." Impact Journals  Oncotarget vol. 8 (31), 50972-50986.
      22-03-2017

    2016

    • Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C, Bowden N, Ashton J-P, Walczak H, Firmin D, Krams R, Mason JC, Haskard DO, Sherwin S, Ridger V, Chico TJA and Evans PC (2016). "Zebrafish Model for Functional Screening of Flow-Responsive Genes." Wolters Kluwer Health, Inc  Arterioscler Thromb Vasc Biol vol. 37 (1), 130-143.
      10-11-2016
    • Pedrigi RM, Papadimitriou KI, Kondiboyina A, Sidhu S, Chau J, Patel MB, Baeriswyl DC, Drakakis EM and Krams R (2016). "Disturbed Cyclical Stretch of Endothelial Cells Promotes Nuclear Expression of the Pro-Atherogenic Transcription Factor NF-κB." Springer Nature  Ann Biomed Eng vol. 45 (4), 898-909.
      27-10-2016
    • Pedrigi RM, Mehta V, Bovens SM, Mohri Z, Poulsen CB, Gsell W, Tremoleda JL, Towhidi L, De Silva R, Petretto E and Krams R (2016). "Influence of shear stress magnitude and direction on atherosclerotic plaque composition." Royal Society Open Science vol. 3 (10)
      19-10-2016
    • Kis Z, Rodin T, Zafar A, Lai Z, Freke G, Fleck O, Del Rio Hernandez A, Towhidi L, Pedrigi RM, Homma T and Krams R (2016). "Development of a synthetic gene network to modulate gene expression by mechanical forces." Springer Nature  Sci Rep vol. 6, 29643-29643.
      12-07-2016
    • Denis J-F, Scheckenbach L, Pfenniger A, Meens M, Krams R, Miquerol L, Taffet S, Chanson M, Delmar M and Kwak B (2016). "0109 : Connexin40 controls endothelial activation by dampening NF B activation." Archives of Cardiovascular Diseases Supplements vol. 8 (3), 203-203.
      01-04-2016
    • Towhidi L, Khodadadi D, Maimari N, Pedrigi RM, Ip H, Kis Z, Kwak BR, Petrova TW, Delorenzi M and Krams R (2016). "Comparison between direct and reverse electroporation of cells in situ: A simulation study." Physiological Reports vol. 4 (6), 1-14.
      01-03-2016
    • Seneviratne AN, Cole JE, Goddard ME, Park I, Mohri Z, Sansom S, Udalova I, Krams R and Monaco C (2016). "Corrigendum to Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques [J Mol Cell Cardiol, 89B (2015) 168-172]." Journal of Molecular and Cellular Cardiology vol. 91
      01-02-2016
    • Maimari N, Pedrigi RM, Russo A, Broda K and Krams R (2016). "Integration of flow studies for robust selection of mechanoresponsive genes." Thrombosis and Haemostasis vol. 115 (3), 474-483.
      01-01-2016

    2015

    • Seneviratne AN, Cole JE, Goddard ME, Park I, Mohri Z, Sansom S, Udalova I, Krams R and Monaco C (2015). "Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques." Journal of Molecular and Cellular Cardiology vol. 89, 168-172.
      01-12-2015
    • Antonacci G, Pedrigi RM, Kondiboyina A, Mehta VV, De Silva R, Paterson C, Krams R and Török P (2015). "Quantification of plaque stiffness by Brillouin microscopy in experimental thin cap fibroatheroma." Journal of The Royal Society Interface vol. 12 (112)
      06-11-2015
    • Pfenniger A, Meens MJ, Pedrigi RM, Foglia B, Sutter E, Pelli G, Rochemont V, Petrova TV, Krams R and Kwak BR (2015). "Shear stress-induced atherosclerotic plaque composition in ApoE-/- mice is modulated by connexin37." Atherosclerosis vol. 243 (1), 1-10.
      01-11-2015
    • Poulsen CB, Mehta VV, Holm NR, Pareek N, Post AL, Kilic ID, Banya WAS, Dall'Ara G, Mattesini A, Bjørklund MM, Andersen NP, Grøndal AK, Petretto E, Foin N, Davies JE, Di Mario C, Bentzon JF, Bøtker HE, Falk E, Krams R and De Silva R (2015). "Inducing persistent flow disturbances accelerates atherogenesis and promotes thin cap fibroatheroma development in D374Y-PCSK9 hypercholesterolemic minipigs." Circulation vol. 132 (11), 1003-1012.
      15-09-2015
    • Shamout FE, Pouliopoulos AN, Lee P, Bonaccorsi S, Towhidi L, Krams R and Choi JJ (2015). "Enhancement of Non-Invasive Trans-Membrane Drug Delivery Using Ultrasound and Microbubbles During Physiologically Relevant Flow." Ultrasound in Medicine and Biology vol. 41 (9), 2435-2448.
      01-09-2015
    • Dent MR, López-Duarte I, Dickson CJ, Geoghegan ND, Cooper JM, Gould IR, Krams R, Bull JA, Brooks NJ and Kuimova MK (2015). "Imaging phase separation in model lipid membranes through the use of BODIPY based molecular rotors." Physical Chemistry Chemical Physics vol. 17 (28), 18393-18402.
      28-07-2015
    • Kis Z, Pereira HSA, Homma T, Pedrigi RM and Krams R (2015). "Mammalian synthetic biology: Emerging medical applications." Journal of The Royal Society Interface vol. 12 (106)
      06-05-2015

    2014

    • Mohri Z, Rowland EM, Clarke LA, De Luca A, Peiffer V, Krams R, Sherwin SJ and Weinberg PD (2014). "Elevated uptake of plasma macromolecules by regions of arterial wall predisposed to plaque instability in a mouse model." Plos One vol. 9 (12)
      22-12-2014
    • Towhidi L, Maimari N, Kis Z, Khodadadi D and Krams R (2014). "A novel high-throughput platform for siRNA transfection of primary mammalian cells." Atherosclerosis vol. 237 (2)
      01-12-2014
    • Maimari N, Towhidi L, Oh D, Broda K, Russo A and Krams R (2014). "A novel integrated platform for gene network inference and validation: beyond the dream consortium." Atherosclerosis vol. 237 (2)
      01-12-2014
    • Pereira G and Krams R (2014). "Forecasting vulnerable plaque response to aemorheological flow." Atherosclerosis vol. 237 (2)
      01-12-2014
    • Mehta VV, Pedrigi RM, Bovens SM, Tremoleda JL, Gsell W and Krams R (2014). "Longitudinal predictive analysis of vulnerable plaques in a mouse model of atherosclerosis." Atherosclerosis vol. 237 (2)
      01-12-2014
    • Maimari N, Broda K, Kakas A, Russo A and Krams R (2014). "Symbolic representation and inference of regulatory networks: uncovering mechanosensitive gene networks." Atherosclerosis vol. 237 (2)
      01-12-2014
    • Maimari N, Broda K, Kakas A, Krams R and Russo A (2014). "Symbolic Representation and Inference of Regulatory Network Structures." In Logical Modeling of Biological Systems 1-48.
      09-09-2014
    • Cuhlmann S, Gsell W, Van der Heiden K, Habib J, Tremoleda JL, Khalil M, Turkheimer F, Meens MJ, Kwak BR, Bird J, Davenport AP, Clark J, Haskard D, Krams R, Jones H and Evans PC (2014). "In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18F-FEDAA1106." Mol Imaging vol. 13 (6)
      01-08-2014
    • Cuhlmann S, Gsell W, Van Der Heiden K, Habib J, Tremoleda JL, Khalil M, Turkheimer F, Meens MJ, Kwak BR, Bird J, Davenport AP, Clark J, Haskard D, Krams R, Jones H and Evans PC (2014). "In vivo mapping of vascular inflammation using the translocator protein tracer 18F-FEDAA1106." Molecular Imaging vol. 13 (6)
      01-08-2014
    • Kwak BR, Bäck M, Bochaton-Piallat ML, Caligiuri G, Daemen MJAP, Davies PF, Hoefer IE, Holvoet P, Jo H, Krams R, Lehoux S, Monaco C, Steffens S, Virmani R, Weber C, Wentzel JJ and Evans PC (2014). "Biomechanical factors in atherosclerosis: Mechanisms and clinical implications." European Heart Journal vol. 35 (43), 3013-3020.
      31-07-2014
    • Caro CG, Seneviratne A, Heraty KB, Monaco C, Burke MG, Krams R, Chang CC, Gilson P and Coppola G (2014). "Erratum: Intimal hyperplasia following implantation of helical-centreline and straight-centreline stents in common carotid arteries in healthy pigs: Influence of intraluminal flow (Journal of the Royal Society Interface (2013) 10, (20130578) DOI: 10.1098/rsif.2013.0578)." Journal of The Royal Society Interface vol. 11 (92)
      06-03-2014
    • Kis Z, Towhidi L, Ip H, Drakakis E, Bharath A and Krams R (2014). "An In situ electroporation and flow device for mechanotransduction studies." In Microarrays: Principles, Applications and Technologies 49-67.

      01-01-2014
    • Pedrigi RM, De Silva R, Bovens SM, Mehta VV, Petretto E and Krams R (2014). "Thin-cap fibroatheroma rupture is associated with a fine interplay of shear and wall stress." Arteriosclerosis, Thrombosis, and Vascular Biology vol. 34 (10), 2224-2231.
      01-01-2014

    2013

    • Caro CG, Seneviratne A, Heraty KB, Monaco C, Burke MG, Krams R, Chang CC, Coppola G and Gilson P (2013). "Intimal hyperplasia following implantation of helical-centreline and straight-centreline stents in common carotid arteries in healthy pigs: Influence of intraluminal flow." Journal of The Royal Society Interface vol. 10 (89)
      06-12-2013
    • Ylä-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Jauhiainen S, Jukema JW, Krams R, Kwak BR, Marx N, Naruszewicz M, Newby A, Pasterkamp G, Serruys PWJC, Waltenberger J, Weber C and Tokgözoglu L (2013). "Stabilization of atherosclerotic plaques: An update." European Heart Journal vol. 34 (42), 3251-3258.
      07-11-2013
    • Seneviratne AN, Cole JE, Goddard ME, Udalova I, Krams R and Monaco C (2013). "M1 macrophages are an early feature of shear stress modulated vulnerable atherosclerotic plaques." European Heart Journal vol. 34 (suppl_1), p2398-p2398.
      02-08-2013
    • Bovens SM, Foin N, O'Clery N, Van Der Heiden K, Cuhlmann S, Carlsen H, Barahona M, Evans PC and Krams R (2013). "Shear stress and nitric oxide transport affect NFkB dynamics in endothelial cells." European Heart Journal vol. 34 (suppl_1), p582-p582.
      02-08-2013
    • Foin N, Sen S, Petraco R, Nijjer S, Torii R, Kousera C, Broyd C, Mehta V, Xu Y, Mayet J, Hughes A, Di Mario C, Krams R, Francis D and Davies J (2013). "Method for percutaneously introducing, and removing, anatomical stenosis of predetermined severity in vivo: The stenotic stent." Journal of Cardiovascular Translational Research vol. 6 (4), 640-648.
      01-08-2013
    • Frueh J, Maimari N, Homma T, Bovens SM, Pedrigi RM, Towhidi L and Krams R (2013). "Systems biology of the functional and dysfunctional endothelium." Cardiovascular Research vol. 99 (2), 334-341.
      15-07-2013
    • Olivon VC, Fraga-Silva RA, Segers D, Demougeot C, de Oliveira AM, Savergnini SS, Berthelot A, de Crom R, Krams R, Stergiopulos N and da Silva RF (2013). "Arginase inhibition prevents the low shear stress-induced development of vulnerable atherosclerotic plaques in ApoE-/- mice." Atherosclerosis vol. 227 (2), 236-243.
      01-04-2013
    • Harrison M, Smith E, Ross E, Krams R, Segers D, Buckley CD, Nash GB and Rainger GE (2013). "The role of platelet-endothelial cell adhesion molecule-1 in atheroma formation varies depending on the site-specific hemodynamic environment." Arteriosclerosis, Thrombosis, and Vascular Biology vol. 33 (4), 694-701.
      01-04-2013
    • Shami A, Gustafsson R, Kalamajski S, Krams R, Segers D, Rauch U, Roos G, Nilsson J, Oldberg A and Hultgårdh-Nilsson A (2013). "Fibromodulin deficiency reduces low-density lipoprotein accumulation in atherosclerotic plaques in apolipoprotein E-null mice." Arteriosclerosis, Thrombosis, and Vascular Biology vol. 33 (2), 354-361.
      01-02-2013

    2012

    • Da Silva RF, Gambillara V, Krams R and Stergiopulos N (2012). "Modulation of arginases by different patterns of shear stress: New signaling pathway in atherogenesis?" Computer Methods in Biomechanics and Biomedical Engineering vol. 10 (SUPPL. 1), 77-78.
      27-12-2012
    • Pfenniger A, Wong C, Sutter E, Cuhlmann S, Dunoyer-Geindre S, Mach F, Horrevoets AJ, Evans PC, Krams R and Kwak BR (2012). "Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells." Journal of Molecular and Cellular Cardiology vol. 53 (2), 299-309.
      01-08-2012
    • Frueh J, Maimari N, Lui Y, Kis Z, Mehta V, Pormehr N, Grant C, Chalkias E, Falck-Hansen M, Bovens S, Pedrigi R, Homma T, Coppola G and Krams R (2012). "Systems and synthetic biology of the vessel wall." Febs Letters vol. 586 (15), 2164-2170.
      16-07-2012
    • Van Bochove GS, Sanders HMHF, De Smet M, Keizer HM, Mulder WJM, Krams R, Strijkers GJ and Nicolay K (2012). "Molecular MR imaging of collagen in mouse atherosclerosis by using paramagnetic CNA35 micelles." European Journal of Inorganic Chemistry (12), 2115-2125.
      01-04-2012
    • Schlueter J, Brand T, Henderson DJ, Boczonadi V, Humbert P, Chaudhry B, Sedmera D, Svatunkova J, Kockova R, Sankova B, Lopez Sanchez C, Franco D, Aranega A, Garcia-Martinez V, Demina E, Miroshikova V, Denisenko A, Schwarzman A, Sanchez-Cabo F, Torroja C, Benguria A, Buchan R, Srivastava P, Martinez F, Barton P, Cook S, Dopazo A, Lara-Pezzi E and Rai H (2012). "Poster session 1." Cardiovascular Research vol. 93 (suppl_1), s9-s45.
      15-03-2012
    • Nanka O, Krejci E, Pesevski Z, Sedmera D, Smart N, Rossdeutsch A, Dube KN, Riegler J, Price AN, Taylor A, Muthurangu V, Turner M, Lythgoe MF, Riley PR, Kryvorot S, Vladimirskaya T, Shved I, Schwarzl M, Seiler S, Huber S, Steendijk P, Maechler H, Truschnig-Wilders M, Pieske B, Post H, Caprio C, Baldini A, Chiavacci E, Dolfi L and Verduci L (2012). "Poster session 3." Cardiovascular Research vol. 93 (suppl_1), s92-s127.
      15-03-2012
    • Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S and Schäfers M (2012). "Implantation of a carotid cuff for triggering shear-stress induced atherosclerosis in mice." Journal of Visualized Experiments (59), 1-6.
      01-01-2012
    • Foin N, Torii R, Mortier P, De Beule M, Viceconte N, Chan PH, Davies JE, Xu XY, Krams R and Di Mario C (2012). "Kissing balloon or sequential dilation of the side branch and main vessel for provisional stenting of bifurcations: Lessons from micro-computed tomography and computational simulations." Jacc: Cardiovascular Interventions vol. 5 (1), 47-56.
      01-01-2012

    2011

    • Gsell W, Cuhlmann S, Van der Heiden K, Tremoleda JL, Khalil M, Clark J, Bird J, Jones H, Krams R and Evans PC (2011). "(18)FEDAA is a more specific probe than (18)FDG for imaging vascular inflammation." European Journal of Nuclear Medicine and Molecular Imaging vol. 38, S210-S210.

      01-10-2011
    • Foin N, Secco GG, Ghilencea L, Krams R and Di Mario C (2011). "Final proximal post-dilatation is necessary after kissing balloon in bifurcation stenting." Eurointervention vol. 7 (5), 597-604.
      01-09-2011
    • Halliday I, Atherton M, Care CM, Collins MW, Evans D, Evans PC, Hose DR, Khir AW, König CS, Krams R, Lawford PV, Lishchuk SV, Pontrelli G, Ridger V, Spencer TJ, Ventikos Y, Walker DC and Watton PN (2011). "Multi-scale interaction of particulate flow and the artery wall." Medical Engineering and Physics vol. 33 (7), 840-848.
      01-09-2011
    • Foin N, Viceconte N, Chan PH, Lindsay AC, Krams R and Di Mario C (2011). "Jailed side branches: Fate of unapposed struts studied with 3D frequency-domain optical coherence tomography." Journal of Cardiovascular Medicine vol. 12 (8), 581-582.
      01-08-2011
    • De Crom R, Leenen P, Nicolay K and Krams R (2011). "Shear stress is a major determinant for getting a heart attack." Hart Bulletin vol. 42 (3), 67-70.

      01-06-2011
    • Cuhlmann S, Van Der Heiden K, Saliba D, Tremoleda JL, Khalil M, Zakkar M, Chaudhury H, Luong LA, Mason JC, Udalova I, Gsell W, Jones H, Haskard DO, Krams R and Evans PC (2011). "Disturbed blood flow induces rela expression via c-Jun N-terminal kinase 1: A novel mode of NF-κB regulation that promotes arterial inflammation." Circulation Research vol. 108 (8), 950-959.
      15-04-2011
    • Zakkar M, Luong LA, Chaudhury H, Ruud O, Punjabi PP, Anderson JR, Mullholand JW, Clements AT, Krams R, Foin N, Athanasiou T, Leen ELS, Mason JC, Haskard DO and Evans PC (2011). "Dexamethasone arterializes venous endothelial cells by inducing mitogen-activated protein kinase phosphatase-1: A novel antiinflammatory treatment for vein grafts?" Circulation vol. 123 (5), 524-532.
      08-02-2011
    • Segers D, Lipton JA, Leenen PJM, Cheng C, Tempel D, Pasterkamp G, Moll FL, de Crom R and Krams R (2011). "Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans." Int J Inflam vol. 2011
      01-01-2011
    • Van Bochove GS, Paulis LEM, Segers D, Mulder WJM, Krams R, Nicolay K and Strijkers GJ (2011). "Contrast enhancement by differently sized paramagnetic MRI contrast agents in mice with two phenotypes of atherosclerotic plaque." Contrast Media and Molecular Imaging vol. 6 (1), 35-45.
      01-01-2011
    • Ylä-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Wouter Jukema J, Krams R, Kwak BR, Marx N, Naruszewicz M, Newby A, Pasterkamp G, Serruys PWJC, Waltenberger J, Weber C and Tokgözoglu L (2011). "Stabilisation of atherosclerotic plaques position paper of the european society of cardiology (ESC) working group on atherosclerosis and vascular biology." Thrombosis and Haemostasis vol. 106 (1), 1-19.
      01-01-2011

    2010

    • Debernardi N, Roijers RB, Krams R, De Crom R, Mutsaers PHA and Van Der Vusse GJ (2010). "Microcalcifications in atherosclerotic lesion of apolipoprotein E-deficient mouse." International Journal of Experimental Pathology vol. 91 (6), 485-494.
      01-12-2010
    • Plata AM, Sherwin SJ and Krams R (2010). "Endothelial nitric oxide production and transport in flow chambers: The importance of convection." Annals of Biomedical Engineering vol. 38 (9), 2805-2816.
      01-09-2010
    • Cuhlmann S, van der Heiden K, Zakkar M, Chaudhury H, Le Anh Luong , Mason J, Haskard DO, Carlsen H, Krams R and Evans PC (2010). "YIA4 C Jun N-terminal kinase promotes endothelial activation at atherosclerosis-susceptible sites by enhancing expression of NF-κB transcription factors." Heart vol. 96 (17)
      26-08-2010
    • Helderman F, Manoch IJ, Breeuwer M, Kose U, Boersma H, van Sambeek MRHM, Pattynama PMT, Schouten O, Poldermans D, Wisselink W, van der Steen AFW and Krams R (2010). "Predicting Patient-Specific Expansion of Abdominal Aortic Aneurysms." Journal of Vascular Surgery vol. 52 (1)
      01-07-2010
    • Krams R, Cuhlmann S, Foin N and Evans P (2010). "Shear stress, inflammation and Atherosclerosis." Artery Research vol. 4 (2), 41-46.
      01-06-2010
    • Van Bochove GS, Straathof R, Krams R, Nicolay K and Strijkers GJ (2010). "MRI-determined carotid artery flow velocities and wall shear stress in a mouse model of vulnerable and stable atherosclerotic plaque." Magnetic Resonance Materials in Physics, Biology and Medicine vol. 23 (2), 77-84.
      01-04-2010
    • Friedman MH, Krams R and Chandran KB (2010). "Flow interactions with cells and tissues: Cardiovascular flows and fluid-structure interactions: Sixth international bio-fluid mechanics symposium and workshop, March 28-30, 2008, Pasadena, California." Annals of Biomedical Engineering vol. 38 (3), 1178-1187.
      01-03-2010
    • Chaudhury H, Zakkar M, Boyle J, Cuhlmann S, Van Der Heiden K, Luong LA, Davis J, Platt A, Mason JC, Krams R, Haskard DO, Clark AR and Evans PC (2010). "C-Jun N-terminal kinase primes endothelial cells at atheroprone sites for apoptosis." Arteriosclerosis, Thrombosis, and Vascular Biology vol. 30 (3), 546-553.
      01-01-2010
    • Helderman F, Manoch IJ, Breeuwer , Kose U, Boersma H, Van Sambeek MRHM, Pattynama PMT, SchoutenO. , Poldermans D, WisselinkW. , Van Der Steen AFW and Krams R (2010). "Predicting patient-specific expansion of abdominal aortic aneurysms." European Journal of Vascular and Endovascular Surgery vol. 40 (1), 47-53.
      01-01-2010

    2009

    • Zakkar M, Van Der Heiden K, Luong LA, Chaudhury H, Cuhlmann S, Hamdulay SS, Krams R, Edirisinghe I, Rahman I, Carlsen H, Haskard DO, Mason JC and Evans PC (2009). "Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state." Arteriosclerosis, Thrombosis, and Vascular Biology vol. 29 (11), 1851-1857.
      01-11-2009
    • Cheng C, Tempel D, van Haperen R, van Damme L, Algür M, Krams R and de Crom R (2009). "Activation of MMP8 and MMP13 by angiotensin II correlates to severe intra-plaque hemorrhages and collagen breakdown in atherosclerotic lesions with a vulnerable phenotype." Atherosclerosis vol. 204 (1), 26-33.
      01-05-2009
    • de Crom R, Cheng C, Helderman F and Krams R (2009). "Large variations in absolute wall shear stress levels within one species and between species." Atherosclerosis vol. 204 (1), 16-17.
      01-05-2009
    • Susa D, van de Engel S, van Damme LCA, Roest HP, Krams R, IJzermans JNM and de Bruin RWF (2009). "Donor pre-treatment with tacrolimus reduces transplant vasculopathy." Pharmacological Research vol. 59 (4), 273-278.
      01-04-2009
    • Foin N, Plata-Garcia A, Cuhlmann S, Evans P, Caro C and Krams R (2009). "SHEAR STRESS AND MASS TRANSPORT AFFECTS NF kappa B DYNAMICS IN ENDOTHELIAL CELLS." Journal of Physiological Sciences vol. 59, 324-324.

      01-01-2009

    2008

    • Segers D, Weinberg P and Krams R (2008). "Atherosclerosis: Cell biology and lipoproteins - Shear stress and inflammation in plaque formation: New evidence." Current Opinion in Lipidology vol. 19 (6), 627-628.
      01-12-2008
    • Segers D, Cheng C, Crom RD, Kirschbaum SWM, Oostlander AE, Helderman F, Wamel AV, Slager CJ, Serruys PW, Steen AFWVD and Krams R (2008). "Monocyte Adhesion in Atherosclerosis: A Biomechanical Approach." Vascular Disease Prevention vol. 2 (1), 227-235.
      01-12-2008
    • Krams R, Breeuwer M and van de Vosse F (2008). "Personalised imaging and biomechanical modelling of large vessels." Medical and Biological Engineering and Computing vol. 46 (11), 1057-1058.
      05-11-2008
    • Robbers-Visser D, Helderman F, Strengers JL, Van Osch-Gevers L, Kapusta L, Pattynama PM, Bogers AJ, Krams R and Helbing WA (2008). "Pulmonary artery size and function after fontan operation at a young age." Journal of Magnetic Resonance Imaging vol. 28 (5), 1101-1107.
      01-11-2008
    • Robbers-Visser D, Helderman F, Strengers JL, van Osch-Gevers L, Kapusta L, Pattynama PM, Bogers AJ, Krams R and Helbing WA (2008). "1057 Pulmonary artery size and function after Fontan operation at young age: assessment with phase contrast magnetic resonance imaging." Journal of Cardiovascular Magnetic Resonance vol. 10 (Suppl 1)
      22-10-2008
    • Ridger V, Krams R, Carpi A and Evans PC (2008). "Hemodynamic parameters regulating vascular inflammation and atherosclerosis: A brief update." Biomedicine and Pharmacotherapy vol. 62 (8), 536-540.
      01-10-2008
    • Zakkar M, Chaudhury H, Sandvik G, Enesa K, Luong LA, Cuhlmann S, Mason JC, Krams R, Clark AR, Haskard DO and Evans PC (2008). "Increased endothelial mitogen-activated protein kinase phosphatase-1 expression suppresses proinflammatory activation at sites that are resistant to atherosclerosis." Circulation Research vol. 103 (7), 726-732.
      26-09-2008
    • Breeuwer M, de Putter S, Kose U, Speelman L, Visser K, Gerritsen F, Hoogeveen R, Krams R, van den Bosch H, Buth J, Gunther T, Wolters B, van Dam E and van de Vosse F (2008). "Towards patient-specific risk assessment of abdominal aortic aneurysm." Medical and Biological Engineering and Computing vol. 46 (11), 1085-1095.
      24-09-2008
    • de Bruin RWF, Susa D, van den Engel S, van Damme LA, Roest HP, Krams R and Jzermans JNMI (2008). "DONOR PRE-TREATMENT WITH TACROLIMUS EDUCES TRANSPLANT VASCULOPATHY." Transplantation vol. 86 (2S)
      27-07-2008
    • da Silva RF, Olivon VC, Segers D, de Crom R, Krams R and Stergiopulos N (2008). "REGULATION OF ARGINASE IN RESPONSE SHEAR STRESS: NEW POTENTIAL THERAPEUTIC TARGET ATHEROSCLEROSIS?" Journal of Biomechanics vol. 41
      01-07-2008
    • Helderman F, Manoch IJ, Breeuwer M, Kose U, Schouten O, Sambeek MRM, Poldermans D, Pattynama PTM, Wisselink W, Steen AFW and Krams R (2008). "A numerical model to predict abdominal aortic aneurysm expansion based on local wall stress and stiffness." Medical and Biological Engineering and Computing vol. 46 (11), 1121-1127.
      03-06-2008
    • Cheng C, Tempel D, Oostlander A, Helderman F, Gijsen F, Wentzel J, Van Haperen R, Haitsma DB, Serruys PW, Van Der Steen AFW, De Crom R and Krams R (2008). "Rapamycin modulates the eNOS vs. shear stress relationship." Cardiovascular Research vol. 78 (1), 123-129.
      01-04-2008
    • Foin N, Evans P and Krams R (2008). "Atherosclerosis: Cell biology and lipoproteins - New developments in imaging of inflammation of the vulnerable plaque." Current Opinion in Lipidology vol. 19 (1), 98-100.
      01-02-2008
    • Van der Heiden K, Hierck BP, Krams R, de Crom R, Cheng C, Baiker M, Pourquie MJBM, Alkemade FE, DeRuiter MC, Gittenberger-de Groot AC and Poelmann RE (2008). "Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis." Atherosclerosis vol. 196 (2), 542-550.
      01-02-2008
    • Segers D, Garcia-Garcia HM, Cheng C, De Crom R, Krams R, Wentzel JJ, Van der Steen AFW, Serruys PW, Leenen PJM and Laman JD (2008). "A primer on the immune system in the pathogenesis and treatment of atherosclerosis." Eurointervention vol. 4 (3), 378-390.
      01-01-2008

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