Prof Rob Krams
MD, PhD

 

All Publications

Page 1 of 5

    2023

    • Çap M, Torii R, Onuma Y, Krams R, Bennett MR, Stone PH, Serruys PW and Bourantas CV (2023). "Editorial: Computational modeling for assessing coronary artery pathophysiology." Frontiers in Cardiovascular Medicine vol. 10
      17-01-2023

    2022

    • Souilhol C, Ayllon BT, Li X, Diagbouga MR, Zhou Z, Canham L, Roddie H, Pirri D, Chambers EV, Dunning MJ, Ariaans M, Li J, Fang Y, Jørgensen HF, Simons M, Krams R, Waltenberger J, Fragiadaki M, Ridger V, De Val S, Francis SE, Chico TJA, Serbanovic-Canic J and Evans PC (2022). "JAG1-NOTCH4 mechanosensing drives atherosclerosis." Science Advances vol. 8 (35)
      02-09-2022
    • Bajaj R, Huang X, Alves N, Weyers J, Levine M, Garg M, Maung S, Bransby K, Torii R, Krams R, Garcia-Garcia H, Mathur A, Baumbach A, Zhang Q, Courtney B and Bourantas C (2022). "TCT-254 Histology-Trained Deep Learning Methodology for Automated Coronary Plaque Component Classification in Combined Intravascular Ultrasound-Optical Coherence Tomography Images." Journal of The American College of Cardiology vol. 80 (12)
      01-09-2022
    • Krams IA, Mennerat A, Krama T, Krams R, Joers P, Elferts D, Luoto S, Rantala MJ and Eliassen S (2022). "Extra-pair paternity explains cooperation in a bird species." Proceedings of The National Academy of Sciences of The United States of America vol. 119 (5)
      01-02-2022

    2021

    • Herault S, Naser J, Carassiti D, Chooi KY, Nikolopoulou R, Font ML, Patel M, Pedrigi R and Krams R (2021). "Mechanosensitive pathways are regulated by mechanosensitive miRNA clusters in endothelial cells." Springer (Part of Springer Nature)  Biophysical Reviews vol. 13 (5), 787-796.
      23-10-2021
    • Naser J, Fogell N, Patel M, Yang P, Krams R, Wentzel JJ, Aben JP and De Silva R (2021). "Moving shear stress towards the clinic: preclinical comparison of optical coherence tomography-based versus angiography-based time-averaged wall shear stress estimations." European Heart Journal vol. 42 (Supplement_1)
      12-10-2021
    • (2021). "Correction: BS18 Profiling endothelial gene expression in coronary atherosclerotic plaques in a human-like D374Y-PCSK9 hyperlipidaemic porcine model." Heart vol. 107 (19), e10-e10.
      14-09-2021
    • Patel M, Savvopoulos F, Berggren CC, Aslanidou L, Timmins LH, de Silva R, Pedrigi RM and Krams R (2021). "Considerations for analysis of endothelial shear stress and strain in FSI models of atherosclerosis." Elsevier  Journal of Biomechanics vol. 128
      28-08-2021

    2020

    • POST AL, CERNOHORSKY P, PEDRIGI RM, STREEKSTRA GJ, D'HOOGHE JNS, ANNEMA JT, STRACKEE SD, KRAMS R, VAN LEEUWEN TG, DE BRUIN DLM and FABER DJ (2020). "3D co-registration algorithm for catheter-based optical coherence tomography." Osa Continuum vol. 3 (10), 2707-2721.
      15-10-2020
    • Bourantas CV, Zanchin T, Torii R, Serruys PW, Karagiannis A, Ramasamy A, Safi H, Coskun AU, Koning G, Onuma Y, Zanchin C, Krams R, Mathur A, Baumbach A, Mintz G, Windecker S, Lansky A, Maehara A, Stone PH, Raber L and Stone GW (2020). "Shear Stress Estimated by Quantitative Coronary Angiography Predicts Plaques Prone to Progress and Cause Events." Jacc: Cardiovascular Imaging vol. 13 (10), 2206-2219.
      01-10-2020
    • Evans RJ, Lavin B, Phinikaridou A, Chooi KY, Mohri Z, Wong E, Boyle JJ, Krams R, Botnar R and Long NJ (2020). "Targeted molecular iron oxide contrast agents for imaging atherosclerotic plaque." Nanotheranostics vol. 4 (4), 184-194.
      01-01-2020

    2019

    • Gijsen F, Katagiri Y, Barlis P, Bourantas C, Collet C, Coskun U, Daemen J, Dijkstra J, Edelman E, Evans P, van der Heiden K, Hose R, Koo B-K, Krams R, Marsden A, Migliavacca F, Onuma Y, Ooi A, Poon E, Samady H, Stone P, Takahashi K, Tang D, Thondapu V, Tenekecioglu E, Timmins L, Torii R, Wentzel J and Serruys P (2019). "Expert recommendations on the assessment of wall shear stress in human coronary arteries: existing methodologies, technical considerations, and clinical applications." Oxford University Press (Oup)  European Heart Journal
      30-09-2019
    • Baumbach A (2019). "Reliable in Vivo Intravascular Imaging Plaque Characterisation: A Challenge Unmet." Elsevier  American Heart Journal
      23-07-2019
    • Mohri Z, Del Rio Hernandez A and Krams R (2019). "The emerging role of YAP/TAZ in mechanotransduction." J Thorac Dis vol. 9 (5), E507-E509.
      01-05-2019
    • Baeriswyl DC, Prionisti I, Peach T, Tsolkas G, Chooi KY, Vardakis J, Morel S, Diagbouga MR, Bijlenga P, Cuhlmann S, Evans P, Kwak BR, Ventikos Y and Krams R (2019). "Disturbed flow induces a sustained, stochastic NF-κB activation which may support intracranial aneurysm growth in vivo." Sci Rep vol. 9 (1), 4738-4738.
      18-03-2019
    • Poulsen CB, Pedrigi RM, Pareek N, Kilic ID, Holm NR, Bentzon JF, Bøtker HE, Falk E, Krams R and de Silva R (2019). "Plaque burden influences accurate classification of fibrous cap atheroma by in vivo optical coherence tomography in a porcine model of advanced coronary atherosclerosis." Eurointervention vol. 14 (10), 1129-1135.
      20-02-2019

    2018

    • Abuammah A, Maimari N, Towhidi L, Frueh J, Chooi KY, Warboys C and Krams R (2018). "New developments in mechanotransduction: Cross talk of the Wnt, TGF-β and Notch signalling pathways in reaction to shear stress." Current Opinion in Biomedical Engineering vol. 5, 96-104.
      01-03-2018

    2017

    • Seneviratne AN, Edsfeldt A, Cole JE, Kassiteridi C, Swart M, Park I, Green P, Khoyratty T, Saliba D, Goddard ME, Sansom SN, Goncalves I, Krams R, Udalova IA and Monaco C (2017). "Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis." American Heart Association, Inc  Circulation vol. 136 (12), 1140-1154.
      11-07-2017
    • Denis J-F, Scheckenbach KEL, Pfenniger A, Meens MJ, Krams R, Miquerol L, Taffet S, Chanson M, Delmar M and Kwak BR (2017). "Connexin40 controls endothelial activation by dampening NFκB activation." Impact Journals  Oncotarget vol. 8 (31), 50972-50986.
      22-03-2017

    2016

    • Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C, Bowden N, Ashton J-P, Walczak H, Firmin D, Krams R, Mason JC, Haskard DO, Sherwin S, Ridger V, Chico TJA and Evans PC (2016). "Zebrafish Model for Functional Screening of Flow-Responsive Genes." Wolters Kluwer Health, Inc  Arterioscler Thromb Vasc Biol vol. 37 (1), 130-143.
      10-11-2016
    • Pedrigi RM, Papadimitriou KI, Kondiboyina A, Sidhu S, Chau J, Patel MB, Baeriswyl DC, Drakakis EM and Krams R (2016). "Disturbed Cyclical Stretch of Endothelial Cells Promotes Nuclear Expression of the Pro-Atherogenic Transcription Factor NF-κB." Springer Nature  Ann Biomed Eng vol. 45 (4), 898-909.
      27-10-2016
    • Pedrigi RM, Mehta V, Bovens SM, Mohri Z, Poulsen CB, Gsell W, Tremoleda JL, Towhidi L, De Silva R, Petretto E and Krams R (2016). "Influence of shear stress magnitude and direction on atherosclerotic plaque composition." Royal Society Open Science vol. 3 (10)
      19-10-2016
    • Kis Z, Rodin T, Zafar A, Lai Z, Freke G, Fleck O, Del Rio Hernandez A, Towhidi L, Pedrigi RM, Homma T and Krams R (2016). "Development of a synthetic gene network to modulate gene expression by mechanical forces." Springer Nature  Sci Rep vol. 6, 29643-29643.
      12-07-2016
    • Denis J-F, Scheckenbach L, Pfenniger A, Meens M, Krams R, Miquerol L, Taffet S, Chanson M, Delmar M and Kwak B (2016). "0109 : Connexin40 controls endothelial activation by dampening NF B activation." Archives of Cardiovascular Diseases Supplements vol. 8 (3), 203-203.
      01-04-2016
    • Towhidi L, Khodadadi D, Maimari N, Pedrigi RM, Ip H, Kis Z, Kwak BR, Petrova TW, Delorenzi M and Krams R (2016). "Comparison between direct and reverse electroporation of cells in situ: A simulation study." Physiological Reports vol. 4 (6), 1-14.
      01-03-2016
    • Seneviratne AN, Cole JE, Goddard ME, Park I, Mohri Z, Sansom S, Udalova I, Krams R and Monaco C (2016). "Corrigendum to Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques [J Mol Cell Cardiol, 89B (2015) 168-172]." Journal of Molecular and Cellular Cardiology vol. 91
      01-02-2016
    • Maimari N, Pedrigi RM, Russo A, Broda K and Krams R (2016). "Integration of flow studies for robust selection of mechanoresponsive genes." Thrombosis and Haemostasis vol. 115 (3), 474-483.
      01-01-2016

    2015

    • Seneviratne AN, Cole JE, Goddard ME, Park I, Mohri Z, Sansom S, Udalova I, Krams R and Monaco C (2015). "Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques." Journal of Molecular and Cellular Cardiology vol. 89, 168-172.
      01-12-2015
    • Antonacci G, Pedrigi RM, Kondiboyina A, Mehta VV, De Silva R, Paterson C, Krams R and Török P (2015). "Quantification of plaque stiffness by Brillouin microscopy in experimental thin cap fibroatheroma." Journal of The Royal Society Interface vol. 12 (112)
      06-11-2015
    • Pfenniger A, Meens MJ, Pedrigi RM, Foglia B, Sutter E, Pelli G, Rochemont V, Petrova TV, Krams R and Kwak BR (2015). "Shear stress-induced atherosclerotic plaque composition in ApoE-/- mice is modulated by connexin37." Atherosclerosis vol. 243 (1), 1-10.
      01-11-2015
    • Poulsen CB, Mehta VV, Holm NR, Pareek N, Post AL, Kilic ID, Banya WAS, Dall'Ara G, Mattesini A, Bjørklund MM, Andersen NP, Grøndal AK, Petretto E, Foin N, Davies JE, Di Mario C, Bentzon JF, Bøtker HE, Falk E, Krams R and De Silva R (2015). "Inducing persistent flow disturbances accelerates atherogenesis and promotes thin cap fibroatheroma development in D374Y-PCSK9 hypercholesterolemic minipigs." Circulation vol. 132 (11), 1003-1012.
      15-09-2015
    • Shamout FE, Pouliopoulos AN, Lee P, Bonaccorsi S, Towhidi L, Krams R and Choi JJ (2015). "Enhancement of Non-Invasive Trans-Membrane Drug Delivery Using Ultrasound and Microbubbles During Physiologically Relevant Flow." Ultrasound in Medicine and Biology vol. 41 (9), 2435-2448.
      01-09-2015
    • Dent MR, López-Duarte I, Dickson CJ, Geoghegan ND, Cooper JM, Gould IR, Krams R, Bull JA, Brooks NJ and Kuimova MK (2015). "Imaging phase separation in model lipid membranes through the use of BODIPY based molecular rotors." Physical Chemistry Chemical Physics vol. 17 (28), 18393-18402.
      28-07-2015
    • Kis Z, Pereira HSA, Homma T, Pedrigi RM and Krams R (2015). "Mammalian synthetic biology: Emerging medical applications." Journal of The Royal Society Interface vol. 12 (106)
      06-05-2015

    2014

    • Mohri Z, Rowland EM, Clarke LA, De Luca A, Peiffer V, Krams R, Sherwin SJ and Weinberg PD (2014). "Elevated uptake of plasma macromolecules by regions of arterial wall predisposed to plaque instability in a mouse model." Plos One vol. 9 (12)
      22-12-2014
    • Towhidi L, Maimari N, Kis Z, Khodadadi D and Krams R (2014). "A novel high-throughput platform for siRNA transfection of primary mammalian cells." Atherosclerosis vol. 237 (2)
      01-12-2014
    • Maimari N, Towhidi L, Oh D, Broda K, Russo A and Krams R (2014). "A novel integrated platform for gene network inference and validation: beyond the dream consortium." Atherosclerosis vol. 237 (2)
      01-12-2014
    • Pereira G and Krams R (2014). "Forecasting vulnerable plaque response to aemorheological flow." Atherosclerosis vol. 237 (2)
      01-12-2014
    • Mehta VV, Pedrigi RM, Bovens SM, Tremoleda JL, Gsell W and Krams R (2014). "Longitudinal predictive analysis of vulnerable plaques in a mouse model of atherosclerosis." Atherosclerosis vol. 237 (2)
      01-12-2014
    • Maimari N, Broda K, Kakas A, Russo A and Krams R (2014). "Symbolic representation and inference of regulatory networks: uncovering mechanosensitive gene networks." Atherosclerosis vol. 237 (2)
      01-12-2014
    • Maimari N, Broda K, Kakas A, Krams R and Russo A (2014). "Symbolic Representation and Inference of Regulatory Network Structures." In Logical Modeling of Biological Systems 1-48.
      09-09-2014
    • Cuhlmann S, Gsell W, Van der Heiden K, Habib J, Tremoleda JL, Khalil M, Turkheimer F, Meens MJ, Kwak BR, Bird J, Davenport AP, Clark J, Haskard D, Krams R, Jones H and Evans PC (2014). "In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18F-FEDAA1106." Mol Imaging vol. 13 (6)
      01-08-2014
    • Cuhlmann S, Gsell W, Van Der Heiden K, Habib J, Tremoleda JL, Khalil M, Turkheimer F, Meens MJ, Kwak BR, Bird J, Davenport AP, Clark J, Haskard D, Krams R, Jones H and Evans PC (2014). "In vivo mapping of vascular inflammation using the translocator protein tracer 18F-FEDAA1106." Molecular Imaging vol. 13 (6)
      01-08-2014
    • Kwak BR, Bäck M, Bochaton-Piallat ML, Caligiuri G, Daemen MJAP, Davies PF, Hoefer IE, Holvoet P, Jo H, Krams R, Lehoux S, Monaco C, Steffens S, Virmani R, Weber C, Wentzel JJ and Evans PC (2014). "Biomechanical factors in atherosclerosis: Mechanisms and clinical implications." European Heart Journal vol. 35 (43), 3013-3020.
      31-07-2014
    • Caro CG, Seneviratne A, Heraty KB, Monaco C, Burke MG, Krams R, Chang CC, Gilson P and Coppola G (2014). "Erratum: Intimal hyperplasia following implantation of helical-centreline and straight-centreline stents in common carotid arteries in healthy pigs: Influence of intraluminal flow (Journal of the Royal Society Interface (2013) 10, (20130578) DOI: 10.1098/rsif.2013.0578)." Journal of The Royal Society Interface vol. 11 (92)
      06-03-2014
    • Kis Z, Towhidi L, Ip H, Drakakis E, Bharath A and Krams R (2014). "An In situ electroporation and flow device for mechanotransduction studies." In Microarrays: Principles, Applications and Technologies 49-67.

      01-01-2014
    • Pedrigi RM, De Silva R, Bovens SM, Mehta VV, Petretto E and Krams R (2014). "Thin-cap fibroatheroma rupture is associated with a fine interplay of shear and wall stress." Arteriosclerosis, Thrombosis, and Vascular Biology vol. 34 (10), 2224-2231.
      01-01-2014

    2013

    • Caro CG, Seneviratne A, Heraty KB, Monaco C, Burke MG, Krams R, Chang CC, Coppola G and Gilson P (2013). "Intimal hyperplasia following implantation of helical-centreline and straight-centreline stents in common carotid arteries in healthy pigs: Influence of intraluminal flow." Journal of The Royal Society Interface vol. 10 (89)
      06-12-2013
    • Ylä-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Jauhiainen S, Jukema JW, Krams R, Kwak BR, Marx N, Naruszewicz M, Newby A, Pasterkamp G, Serruys PWJC, Waltenberger J, Weber C and Tokgözoglu L (2013). "Stabilization of atherosclerotic plaques: An update." European Heart Journal vol. 34 (42), 3251-3258.
      07-11-2013
    • Seneviratne AN, Cole JE, Goddard ME, Udalova I, Krams R and Monaco C (2013). "M1 macrophages are an early feature of shear stress modulated vulnerable atherosclerotic plaques." European Heart Journal vol. 34 (suppl_1), p2398-p2398.
      02-08-2013

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