Prof Rob Krams
MD, PhD
All Publications
Page 2 of 5
2013
- Intimal hyperplasia following implantation of helical-centreline and straight-centreline stents in common carotid arteries in healthy pigs: influence of intraluminal flow†
Gerald C, Seneviratne A, Heraty KB, Monaco C, Burke MG, Krams R, Chang CC, Coppola G and Gilson P
Journal of The Royal Society Interface, The Royal Society vol. 10 (89)
06-12-2013 - Stabilization of atherosclerotic plaques: an update
Ylä-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Jauhiainen S, Jukema JW, Krams R, Kwak BR, Marx N, Naruszewicz M, Newby A, Pasterkamp G, Serruys PWJC, Waltenberger J, Weber C, Tokgözoglu L and Biology EWGOAAV
European Heart Journal, Oxford University Press (Oup) vol. 34 (42), 3251-3258.
21-08-2013 - M1 macrophages are an early feature of shear stress modulated vulnerable atherosclerotic plaques
Seneviratne AN, Cole JE, Goddard ME, Udalova I, Krams R and Monaco C
European Heart Journal, Oxford University Press (Oup) vol. 34 (suppl_1)
02-08-2013 - Shear stress and nitric oxide transport affect NFkB dynamics in endothelial cells
Bovens SM, Foin N, O'Clery N, Van Der Heiden K, Cuhlmann S, Carlsen H, Barahona M, Evans PC and Krams R
European Heart Journal, Oxford University Press (Oup) vol. 34 (suppl_1)
02-08-2013 - Method for Percutaneously Introducing, and Removing, Anatomical Stenosis of Predetermined Severity In Vivo: The “Stenotic Stent”
Foin N, Sen S, Petraco R, Nijjer S, Torii R, Kousera C, Broyd C, Mehta V, Xu Y, Mayet J, Hughes A, Di Mario C, Krams R, Francis D and Davies J
Journal of Cardiovascular Translational Research, Springer Nature vol. 6 (4), 640-648.
04-06-2013 - Systems biology of the functional and dysfunctional endothelium
Frueh J, Maimari N, Homma T, Bovens SM, Pedrigi RM, Towhidi L and Krams R
Cardiovascular Research, Oxford University Press (Oup) vol. 99 (2), 334-341.
06-05-2013 - The Role of Platelet-Endothelial Cell Adhesion Molecule-1 in Atheroma Formation Varies Depending on the Site-Specific Hemodynamic Environment
Harrison M, Smith E, Ross E, Krams R, Segers D, Buckley CD, Nash GB and Rainger GE
Arteriosclerosis Thrombosis and Vascular Biology, Wolters Kluwer vol. 33 (4), 694-701.
31-01-2013 - Arginase inhibition prevents the low shear stress-induced development of vulnerable atherosclerotic plaques in ApoE−/− mice
Olivon VC, Fraga-Silva RA, Segers D, Demougeot C, de Oliveira AM, Savergnini SS, Berthelot A, de Crom R, Krams R, Stergiopulos N and da Silva RF
Atherosclerosis, Elsevier vol. 227 (2), 236-243.
17-01-2013
2012
- Fibromodulin Deficiency Reduces Low-Density Lipoprotein Accumulation in Atherosclerotic Plaques in Apolipoprotein E–Null Mice
Shami A, Gustafsson R, Kalamajski S, Krams R, Segers D, Rauch U, Roos G, Nilsson J, Oldberg Å and Hultgårdh-Nilsson A
Arteriosclerosis Thrombosis and Vascular Biology, Wolters Kluwer vol. 33 (2), 354-361.
29-11-2012 - Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells
Pfenniger A, Wong C, Sutter E, Cuhlmann S, Dunoyer-Geindre S, Mach F, Horrevoets AJ, Evans PC, Krams R and Kwak BR
Journal of Molecular and Cellular Cardiology, Elsevier vol. 53 (2), 299-309.
29-05-2012 - Systems and synthetic biology of the vessel wall
Frueh J, Maimari N, Lui Y, Kis Z, Mehta V, Pormehr N, Grant C, Chalkias E, Falck-Hansen M, Bovens S, Pedrigi R, Homma T, Coppola G and Krams R
Febs Letters, Wiley vol. 586 (15), 2164-2170.
03-05-2012 - Molecular MR Imaging of Collagen in Mouse Atherosclerosis by Using Paramagnetic CNA35 Micelles
van Bochove GS, Sanders HMHF, de Smet M, Keizer HM, Mulder WJM, Krams R, Strijkers GJ and Nicolay K
European Journal of Inorganic Chemistry, Wiley vol. 2012 (12), 2115-2125.
28-03-2012 - Poster session 1
Schlueter J, Brand T, Henderson DJ, Boczonadi V, Humbert P, Chaudhry B, Sedmera D, Svatunkova J, Kockova R, Sankova B, Lopez Sanchez C, Franco D, Aranega A, Garcia-Martinez V, Demina E, Miroshikova V, Denisenko A, Schwarzman A, Sanchez-Cabo F, Torroja C, Benguria A, Buchan R, Srivastava P, Martinez F, Barton P, Cook S, Dopazo A, Lara-Pezzi E and Rai H
Cardiovascular Research, Oxford University Press (Oup) vol. 93 (suppl_1), s9-s45.
15-03-2012 - Poster session 3
Nanka O, Krejci E, Pesevski Z, Sedmera D, Smart N, Rossdeutsch A, Dube KN, Riegler J, Price AN, Taylor A, Muthurangu V, Turner M, Lythgoe MF, Riley PR, Kryvorot S, Vladimirskaya T, Shved I, Schwarzl M, Seiler S, Huber S, Steendijk P, Maechler H, Truschnig-Wilders M, Pieske B, Post H, Caprio C, Baldini A, Chiavacci E, Dolfi L and Verduci L
Cardiovascular Research, Oxford University Press (Oup) vol. 93 (suppl_1), s92-s127.
15-03-2012 - Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice
Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S and Schäfers M
Journal of Visualized Experiments, Myjove (59)
13-01-2012 - Implantation of a carotid cuff for triggering shear-stress induced atherosclerosis in mice.
Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S and Schäfers M
Journal of Visualized Experiments, Myjove (59)
13-01-2012 - Kissing Balloon or Sequential Dilation of the Side Branch and Main Vessel for Provisional Stenting of Bifurcations Lessons From Micro-Computed Tomography and Computational Simulations
Foin N, Torii R, Mortier P, De Beule M, Viceconte N, Chan PH, Davies JE, Xu XY, Krams R and Di Mario C
Jacc Cardiovascular Interventions, Elsevier vol. 5 (1), 47-56.
01-01-2012
2011
- Final proximal post-dilatation is necessary after kissing balloon in bifurcation stenting.
Foin N, Secco GG, Ghilencea L, Krams R and Di Mario C
Eurointervention, Europa Digital & Publishing vol. 7 (5), 597-604.
01-09-2011 - Jailed side branches
Foin N, Viceconte N, Chan PH, Lindsay AC, Krams R and Di Mario C
Journal of Cardiovascular Medicine, Wolters Kluwer vol. 12 (8), 581-582.
01-08-2011 - Shear stress is a major determinant for getting a heart attack
De Crom R, Leenen P, Nicolay K and Krams R
Hart Bulletin vol. 42 (3), 67-70.
01-06-2011 - Disturbed Blood Flow Induces RelA Expression via c-Jun N-Terminal Kinase 1
Cuhlmann S, Van der Heiden K, Saliba D, Tremoleda JL, Khalil M, Zakkar M, Chaudhury H, Luong LA, Mason JC, Udalova I, Gsell W, Jones H, Haskard DO, Krams R and Evans PC
Circulation Research, Wolters Kluwer vol. 108 (8), 950-959.
24-02-2011 - Dexamethasone Arterializes Venous Endothelial Cells by Inducing Mitogen-Activated Protein Kinase Phosphatase-1
Zakkar M, Luong LA, Chaudhury H, Ruud O, Punjabi PP, Anderson JR, Mullholand JW, Clements AT, Krams R, Foin N, Athanasiou T, Leen ELS, Mason JC, Haskard DO and Evans PC
Circulation, Wolters Kluwer vol. 123 (5), 524-532.
24-01-2011 - 18FEDAA is a more specific probe than 18FDG for imaging vascular inflammation
Gsell W, Cuhlmann S, Van der Heiden K, Tremoleda JL, Khalil M, Clark J, Bird J, Jones H, Krams R and Evans PC
European Journal of Nuclear Medicine and Molecular Imaging vol. 38, S210-S210.
01-01-2011 - Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans
Segers D, Lipton JA, Leenen PJM, Cheng C, Tempel D, Pasterkamp G, Moll FL, de Crom R and Krams R
International Journal of Inflammation, Hindawi vol. 2011 (1)
01-01-2011 - Stabilisation of atherosclerotic plaques
Ylä-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Jukema JW, Krams R, Kwak BR, Marx N, Naruszewicz M, Newby A, Pasterkamp G, Serruys PWJC, Waltenberger J, Weber C and Tokgözoglu L
Thrombosis and Haemostasis, Thieme vol. 106 (01), 1-19.
01-01-2011
2010
- Multi-scale interaction of particulate flow and the artery wall
Halliday I, Atherton M, Care CM, Collins MW, Evans D, Evans PC, Hose DR, Khir AW, König CS, Krams R, Lawford PV, Lishchuk SV, Pontrelli G, Ridger V, Spencer TJ, Ventikos Y, Walker DC and Watton PN
Medical Engineering & Physics, Elsevier vol. 33 (7), 840-848.
29-10-2010 - Contrast enhancement by differently sized paramagnetic MRI contrast agents in mice with two phenotypes of atherosclerotic plaque
van Bochove GS, Paulis LEM, Segers D, Mulder WJM, Krams R, Nicolay K and Strijkers GJ
Contrast Media & Molecular Imaging, Wiley vol. 6 (1), 35-45.
29-09-2010 - Microcalcifications in atherosclerotic lesion of apolipoprotein E‐deficient mouse
Debernardi N, Roijers RB, Krams R, De Crom R, Mutsaers PHA and Van Der Vusse GJ
International Journal of Experimental Pathology, Wiley vol. 91 (6), 485-494.
27-08-2010 - YIA4 C Jun N-terminal kinase promotes endothelial activation at atherosclerosis-susceptible sites by enhancing expression of NF-κB transcription factors
Cuhlmann S, van der Heiden K, Zakkar M, Chaudhury H, Luong LA, Mason J, Haskard DO, Carlsen H, Krams R and Evans PC
Heart, Bmj vol. 96 (17)
26-08-2010 - Endothelial Nitric Oxide Production and Transport in Flow Chambers: The Importance of Convection
Plata AM, Sherwin SJ and Krams R
Annals of Biomedical Engineering, Springer Nature vol. 38 (9), 2805-2816.
14-04-2010 - Predicting Patient-Specific Expansion of Abdominal Aortic Aneurysms
Helderman F, Manoch IJ, Breeuwer M, Kose U, Boersma H, van Sambeek MRHM, Pattynama PMT, Schouten O, Poldermans D, Wisselink W, van der Steen AFW and Krams R
European Journal of Vascular and Endovascular Surgery, Elsevier vol. 40 (1), 47-53.
25-03-2010 - MRI-determined carotid artery flow velocities and wall shear stress in a mouse model of vulnerable and stable atherosclerotic plaque
van Bochove GS, Straathof R, Krams R, Nicolay K and Strijkers GJ
Magnetic Resonance Materials in Physics, Biology and Medicine, Springer Nature vol. 23 (2), 77-84.
13-03-2010 - Flow Interactions with Cells and Tissues: Cardiovascular Flows and Fluid–Structure Interactions
Friedman MH, Krams R and Chandran KB
Annals of Biomedical Engineering, Springer Nature vol. 38 (3), 1178-1187.
14-01-2010 - c-Jun N-Terminal Kinase Primes Endothelial Cells at Atheroprone Sites for Apoptosis
Chaudhury H, Zakkar M, Boyle J, Cuhlmann S, van der Heiden K, Luong LA, Davis J, Platt A, Mason JC, Krams R, Haskard DO, Clark AR and Evans PC
Arteriosclerosis Thrombosis and Vascular Biology, Wolters Kluwer vol. 30 (3), 546-553.
07-01-2010 - Shear stress, inflammation and Atherosclerosis
Krams R, Cuhlmann S, Foin N and Evans P
Artery Research, Springer Nature vol. 4 (2), 41-46.
01-01-2010
2009
- Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State
Zakkar M, Van der Heiden K, Luong LA, Chaudhury H, Cuhlmann S, Hamdulay SS, Krams R, Edirisinghe I, Rahman I, Carlsen H, Haskard DO, Mason JC and Evans PC
Arteriosclerosis Thrombosis and Vascular Biology, Wolters Kluwer vol. 29 (11), 1851-1857.
03-09-2009 - Activation of MMP8 and MMP13 by angiotensin II correlates to severe intra-plaque hemorrhages and collagen breakdown in atherosclerotic lesions with a vulnerable phenotype
Cheng C, Tempel D, van Haperen R, van Damme L, Algür M, Krams R and de Crom R
Atherosclerosis, Elsevier vol. 204 (1), 26-33.
24-01-2009 - SHEAR STRESS AND MASS TRANSPORT AFFECTS NFκB DYNAMICS IN ENDOTHELIAL CELLS
Foin N, Plata-Garcia A, Cuhlmann S, Evans P, Caro C and Krams R
Journal of Physiological Sciences vol. 59, 324-324.
01-01-2009
2008
- Donor pre-treatment with tacrolimus reduces transplant vasculopathy
Susa D, van de Engel S, van Damme LCA, Roest HP, Krams R, IJzermans JNM and de Bruin RWF
Pharmacological Research, Elsevier vol. 59 (4), 273-278.
30-12-2008 - Atherosclerosis: cell biology and lipoproteins - shear stress and inflammation in plaque formation: new evidence
Segers D, Weinberg P and Krams R
Current Opinion in Lipidology, Wolters Kluwer vol. 19 (6), 627-628.
01-12-2008 - Monocyte Adhesion in Atherosclerosis: A Biomechanical Approach
Segers D, Cheng C, Crom RD, Kirschbaum SWM, Oostlander AE, Helderman F, Wamel AV, Slager CJ, Serruys PW, Steen AFWVD and Krams R
Vascular Disease Prevention, Bentham Science Publishers vol. 2 (1), 227-235.
01-12-2008 - A primer on the immune system in the pathogenesis and treatment of atherosclerosis.
Segers D, Garcia-Garcia HM, Cheng C, de Crom R, Krams R, Wentzel JJ, van der Steen AFW, Serruys PW, Leenen PJM and Laman JD
Eurointervention, Europa Digital & Publishing vol. 4 (3), 378-390.
01-11-2008 - Personalised imaging and biomechanical modelling of large vessels
Krams R, Breeuwer M and van de Vosse F
Medical & Biological Engineering & Computing, Springer Nature vol. 46 (11), 1057-1058.
01-11-2008 - Pulmonary artery size and function after Fontan operation at a young age
Robbers‐Visser D, Helderman F, Strengers JL, van Osch‐Gevers L, Kapusta L, Pattynama PM, Bogers AJ, Krams R and Helbing WA
Journal of Magnetic Resonance Imaging, Wiley vol. 28 (5), 1101-1107.
28-10-2008 - 1057 Pulmonary artery size and function after Fontan operation at young age: assessment with phase contrast magnetic resonance imaging
Robbers-Visser D, Helderman F, Strengers JL, van Osch-Gevers L, Kapusta L, Pattynama PM, Bogers AJ, Krams R and Helbing WA
Journal of Cardiovascular Magnetic Resonance, Elsevier vol. 10
01-10-2008 - Towards patient-specific risk assessment of abdominal aortic aneurysm
Breeuwer M, de Putter S, Kose U, Speelman L, Visser K, Gerritsen F, Hoogeveen R, Krams R, van den Bosch H, Buth J, Gunther T, Wolters B, van Dam E and van de Vosse F
Medical & Biological Engineering & Computing, Springer Nature vol. 46 (11), 1085-1095.
23-09-2008 - Large variations in absolute wall shear stress levels within one species and between species
de Crom R, Cheng C, Helderman F and Krams R
Atherosclerosis, Elsevier vol. 204 (1), 16-17.
22-08-2008 - Increased Endothelial Mitogen-Activated Protein Kinase Phosphatase-1 Expression Suppresses Proinflammatory Activation at Sites That Are Resistant to Atherosclerosis
Zakkar M, Chaudhury H, Sandvik G, Enesa K, Luong LA, Cuhlmann S, Mason JC, Krams R, Clark AR, Haskard DO and Evans PC
Circulation Research, Wolters Kluwer vol. 103 (7), 726-732.
21-08-2008 - Hemodynamic parameters regulating vascular inflammation and atherosclerosis: A brief update
Ridger V, Krams R, Carpi A and Evans PC
Biomedicine & Pharmacotherapy, Elsevier vol. 62 (8), 536-540.
08-08-2008 - DONOR PRE-TREATMENT WITH TACROLIMUS EDUCES TRANSPLANT VASCULOPATHY
de Bruin RWF, Susa D, van den Engel S, van Damme LA, Roest HP, Krams R and Jzermans JNMI
Transplantation, Wolters Kluwer vol. 86 (2S)
27-07-2008