Prof Martin Knight
BEng, MSc, PhD, FHEA

 

Key Publications

  • Thompson C, Mcfie M, Chapple J, BEALES P and Knight M (2021). "Polycystin-2 is required for chondrocyte mechanotransduction and traffics to the primary cilium in response to mechanical stimulation." Mdpi Ag  International Journal of Molecular Sciences 
    21-04-2021
  • Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D, Chakravarty P, Jones RR, Montfort A, Dowe T, Gribben J, Jones JL, Kocher HM, Serody JS, Vincent BG, Connelly J, Brenton JD, Chelala C, Cutillas PR, Lockley M, Bessant C, Knight M and Balkwill FR (2017). "Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers." Cancer Discov 
    01-12-2017
  • KNIGHT MM, Thompson CL, Wiles A and Poole CA (2016). "Lithium chloride modulates chondrocyte primary cilia and inhibits hedgehog signalling." Federation of American Society of Experimental Biology (Faseb)  The Faseb Journal 
    01-02-2016
  • McMurray RJ, Wann AKT, Thompson CL, Connelly JT and Knight MM (2013). "Surface topography regulates wnt signaling through control of primary cilia structure in mesenchymal stem cells." Sci Rep  vol. 3,
    18-12-2013
  • Wann AKT and Knight MM (2012). "Primary cilia elongation in response to interleukin-1 mediates the inflammatory response." Cellular and Molecular Life Sciences  vol. 69, (17) 2967-2977.
    01-09-2012

All Publications

    2021

    • Inamdar SR, Prévost S, Terrill NJ, Knight MM and Gupta HS (2021). "Reversible changes in the 3D collagen fibril architecture during cyclic loading of healthy and degraded cartilage." Elsevier  Acta Biomaterialia vol. 136, 314-326.
      24-11-2021
    • Malacrida B, Nichols S, Maniati E, Jones R, Delanie-Smith R, Roozitalab R, Tyler EJ, Thomas M, Boot G, Mackerodt J, Lockley M, Knight MM, Balkwill FR and Pearce OMT (2021). "A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion." Iscience vol. 24 (6)
      25-06-2021
    • Delaine-Smith RM, Maniati E, Malacrida B, Nichols S, Roozitalab R, Jones RR, Lecker LSM, Pearce OMT, Knight MM and Balkwill FR (2021). "Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer." Iscience vol. 24 (6)
      25-06-2021
    • Verbruggen SW, Thompson CL, Duffy MP, Lunetto S, Nolan J, Pearce OMT, Jacobs CR and Knight MM (2021). "Mechanical stimulation modulates osteocyte regulation of cancer cell phenotype." Cancers vol. 13 (12)
      02-06-2021
    • Thompson C, Mcfie M, Chapple J, BEALES P and Knight M (2021). "Polycystin-2 is required for chondrocyte mechanotransduction and traffics to the primary cilium in response to mechanical stimulation." Mdpi Ag  International Journal of Molecular Sciences
      21-04-2021
    • Wu H, Wang Z, Liu S, Meng H, Shelton JC, Thompson CL, Fu S and Knight MM (2021). "Sub-toxic levels of cobalt ions impair mechanostranduction via HDAC6-depedent primary cilia shortening." Biochem Biophys Res Commun
      15-04-2021
    • Thompson CL, Fu S, Heywood HK, Knight MM and Thorpe SD (2021). "Corrigendum: Mechanical Stimulation: A Crucial Element of Organ-on-Chip Models (Front. Bioeng. Biotechnol., (2020), 8, 602646, 10.3389/fbioe.2020.602646)." Frontiers in Bioengineering and Biotechnology vol. 9
      18-02-2021
    • Delaine-Smith R, Maniati E, Malacrida B, Nichols S, Roozitalab R, Jones R, Lecker L, Pearce O, Knight M and Balkwill F (2021). "Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer.", Editors: Balkwill F. Biorxiv.Org
      02-02-2021
    • Fu S, Meng H, Inamdar S, Das B, Gupta H, Wang W, Thompson C and Knight M (2021). "Activation of TRPV4 by mechanical, osmotic or pharmaceutical stimulation is anti-inflammatory blocking IL-1β mediated articular cartilage matrix destruction.", Editors: Block JA. Elsevier  Osteoarthritis and Cartilage
      01-01-2021

    2020

    2019

    • Walker RV, Keynton JL, Grimes DT, Sreekumar V, Williams DJ, Esapa C, Wu D, Knight MM and Norris DP (2019). "Ciliary exclusion of Polycystin-2 promotes kidney cystogenesis in an autosomal dominant polycystic kidney disease model." Nature Communications vol. 10 (1)
      01-12-2019
    • Inamdar SR, Barbieri E, Terrill NJ, Knight MM and Gupta HS (2019). "Proteoglycan degradation mimics static compression by altering the natural gradients in fibrillar organisation in cartilage." Elsevier  Acta Biomaterialia vol. 97, 437-450.
      30-07-2019
    • Fu S, Thompson CL, Ali A, Wang W, Chapple JP, Mitchison HM, Beales PL, Wann AKT and Knight MM (2019). "Mechanical loading inhibits cartilage inflammatory signalling via an HDAC6 and IFT-dependent mechanism regulating primary cilia elongation." Osteoarthritis and Cartilage vol. 27 (7), 1064-1074.
      01-07-2019
    • Delaine-Smith R, Wright N, Hanley C, Hanwell R, Bhome R, Bullock M, Drifka C, Eliceiri K, Thomas G, Knight M, Mirnezami A and Peake N (2019). "Transglutaminase-2 Mediates the Biomechanical Properties of the Colorectal Cancer Tissue Microenvironment that Contribute to Disease Progression." Mdpi Ag  Cancers
      21-05-2019
    • Harris C, THORPE SD, Rushwan S, Wang W, THOMPSON C, Peacock J, KNIGHT M, Gooptu B and Greenough A (2019). "An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation." Elsevier  Journal of Biomechanics
      22-03-2019
    • O’Toole SM, Watson DS, Novoselova TV, Romano LEL, King PJ, Bradshaw TY, Thompson CL, Knight MM, Sharp TV, Barnes MR, Srirangalingam U, Drake WM and Chapple JP (2019). "Oncometabolite induced primary cilia loss in pheochromocytoma." Endocrine-Related Cancer vol. 26 (1), 165-180.
      01-01-2019

    2018

    • Rowson DT, Shelton JC, Screen HRC and Knight MM (2018). "Mechanical loading induces primary cilia disassembly in tendon cells via TGFβ and HDAC6." Scientific Reports vol. 8 (1)
      01-12-2018
    • Xu J, Nyga A, Li W, Zhang X, Gavara N, Knight MM and Shelton JC (2018). "Cobalt ions stimulate a fibrotic response through matrix remodelling, fibroblast contraction and release of pro-fibrotic signals from macrophages." European Cells and Materials vol. 36, 142-155.
      01-07-2018
    • Kenny FN, Drymoussi Z, Delaine-Smith R, Kao AP, Laly AC, Knight MM, Philpott MP and Connelly JT (2018). "Tissue stiffening promotes keratinocyte proliferation through activation of epidermal growth factor signaling." Journal of Cell Science vol. 131 (10), 215780-215780.
      15-05-2018
    • Xu J, Yang J, Nyga A, Ehteramyan M, Moraga A, Wu Y, Zeng L, Knight MM and Shelton JC (2018). "Cobalt (II) ions and nanoparticles induce macrophage retention by ROS-mediated down-regulation of RhoA expression." Acta Biomater vol. 72, 434-446.
      09-04-2018

    2017

    • Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D, Chakravarty P, Jones RR, Montfort A, Dowe T, Gribben J, Jones JL, Kocher HM, Serody JS, Vincent BG, Connelly J, Brenton JD, Chelala C, Cutillas PR, Lockley M, Bessant C, Knight M and Balkwill FR (2017). "Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers." Cancer Discov
      01-12-2017
    • Gambassi S, Geminiani M, Thorpe SD, Bernardini G, Millucci L, Braconi D, Orlandini M, Thompson CL, Petricci E, Manetti F, Taddei M, Knight MM and Santucci A (2017). "Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria." Journal of Cellular Physiology vol. 232 (11), 3103-3111.
      01-11-2017
    • Thompson CL, Plant JC, Wann AK, Bishop CL, Novak P, Mitchison HM, Beales PL, Chapple JP and Knight MM (2017). "Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling." Eur Cell Mater vol. 34, 128-141.
      20-09-2017
    • Inamdar SR, Knight DP, Terrill NJ, Karunaratne A, Cacho-Nerin F, Knight MM and Gupta HS (2017). "The Secret Life of Collagen: Temporal Changes in Nanoscale Fibrillar Pre-Strain and Molecular Organization During Physiological Loading of Cartilage." Acs Nano
      11-08-2017
    • Zhang J, Dalbay MT, Luo X, Vrij E, Barbieri D, Moroni L, de Bruijn JD, van Blitterswijk CA, Chapple JP, Knight MM and Yuan H (2017). "Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis." Acta Biomater vol. 57, 487-497.
      15-07-2017
    • THORPE SD, Gambassi S, Thompson CL, Chandrakumar C, Santucci A and Knight MM (2017). "Reduced Primary Cilia Length and Altered Arl13b Expression Are Associated with Deregulated Chondrocyte Hedgehog Signalling in Alkaptonuria." John Wiley & Sons Inc.  Journal of Cellular Physiology
      03-02-2017

    2016

    • Delaine-Smith RM, Burney S, Balkwill FR and Knight MM (2016). "Experimental validation of a flat punch indentation methodology calibrated against unconfined compression tests for determination of soft tissue biomechanics." Elsevier  Journal of The Mechanical Behavior of Biomedical Materials vol. 60, 401-415.
      01-07-2016
    • Sliogeryte K, Botto L, Lee DA and Knight MM (2016). "Chondrocyte dedifferentiation increases cell stiffness by strengthening membrane-actin adhesion." Elsevier  Osteoarthritis and Cartilage vol. 24 (5), 912-920.
      01-05-2016
    • Rowson D, Knight MM and Screen HRC (2016). "Zonal variation in primary cilia elongation correlates with localized biomechanical degradation in stress deprived tendon." J Orthop Res vol. 34 (12), 2146-2153.
      23-03-2016
    • KNIGHT MM, wang W, wang Z, wann A, thompson C and hassen A (2016). "IFT88 influences chondrocyte actin organization and biomechanics." Osteoarthritis and Cartilage
      01-03-2016
    • KNIGHT MM, Thompson CL, Wiles A and Poole CA (2016). "Lithium chloride modulates chondrocyte primary cilia and inhibits hedgehog signalling." Federation of American Society of Experimental Biology (Faseb)  The Faseb Journal
      01-02-2016
    • Sliogeryte K, Thorpe SD, Wang Z, Thompson CL, Gavara N and Knight MM (2016). "Differential effects of LifeAct-GFP and actin-GFP on cell mechanics assessed using micropipette aspiration." Elsevier  Journal of Biomechanics vol. 49 (2), 310-317.
      25-01-2016

    2015

    • Thompson CL, Patel R, Kelly T-AN, Wann AKT, Hung CT, Chapple JP and Knight MM (2015). "Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1β." Arthritis Research & Therapy vol. 17 (1)
      24-12-2015
    • Tan AR, VandenBerg CD, Attur M, Abramson SB, Knight MM, Bulinski JC, Ateshian GA, Cook JL and Hung CT (2015). "Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult." Arthritis Res Ther vol. 17, 361-361.
      14-12-2015
    • Thompson CL, Poole CA and Knight MM (2015). "Lithium chloride modulates chondrocyte primary cilia and inhibits Hedgehog signaling." Federation of American Society of Experimental Biology  The Faseb Journal vol. 100 (4), A39-A40.
      23-10-2015
    • Chen J, Bader DL, Lee DA and Knight MM (2015). "FINITE ELEMENT ANALYSIS of MECHANICAL DEFORMATION of CHONDROCYTE to 2D SUBSTRATE and 3D SCAFFOLD." Journal of Mechanics in Medicine and Biology vol. 15 (5)
      01-10-2015
    • KNIGHT MM, Thompson CL, Yasmin H, Varone A, Wiles A and Poole CA (2015). "Lithium chloride prevents interleukin- 1β induced cartilage degradation and loss of mechanical properties." Wiley: 12 Months  Journal of Orthopaedic Research
      01-10-2015
    • Dalbay MT, Thorpe SD, Connelly JT, Chapple JP and Knight MM (2015). "Adipogenic differentiation of hMSCs is mediated by recruitment of IGF-1r onto the primary cilium associated with cilia elongation." Stem Cells vol. 33 (6), 1952-1961.
      01-06-2015
    • Wang Z, Irianto J, Kazun S, Wang W and Knight MM (2015). "The rate of hypo-osmotic challenge influences regulatory volume decrease (RVD) and mechanical properties of articular chondrocytes." Osteoarthritis and Cartilage vol. 23 (2), 289-299.
      01-02-2015

    2014

    2013

    • McMurray RJ, Wann AKT, Thompson CL, Connelly JT and Knight MM (2013). "Surface topography regulates wnt signaling through control of primary cilia structure in mesenchymal stem cells." Sci Rep vol. 3
      18-12-2013
    • Wann AK, Thompson CL, Chapple JP and Knight MM (2013). "Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium." Cilia vol. 2 (1)
      13-12-2013
    • Shafat M, Rajakumar K, Syme H, Buchholz N and Knight MM (2013). "Stent encrustation in feline and human artificial urine: does the low molecular weight composition account for the difference?" Urolithiasis vol. 41 (6), 481-486.
      01-11-2013
    • Hernandez-Hernandez V, Pravincumar P, Diaz-Font A, May-Simera H, Jenkins D, Knight M and Beales PL (2013). "Bardet-Biedl syndrome proteins control the cilia length through regulation of actin polymerization." Human Molecular Genetics vol. 22 (19), 3858-3868.
      01-10-2013
    • Irianto J, Swift J, Martins RP, McPhail GD, Knight MM, Discher DE and Lee DA (2013). "Osmotic challenge drives rapid and reversible chromatin condensation in chondrocytes." Biophys J vol. 104 (4), 759-769.
      19-02-2013
    • Hosny NA, Song M, Connelly JT, Ameer-Beg S, Knight MM and Wheeler AP (2013). "Correction: Super-Resolution Imaging Strategies for Cell Biologists Using a Spinning Disk Microscope." Plos One vol. 8 (12)
      01-01-2013
    • Hosny NA, Song M, Knight MM and Wheeler AP (2013). "Super-resolution imaging strategies for Cell Biologists using a spinning disk microscope." Molecular Biology of The Cell vol. 24

      01-01-2013
    • Hosny NA, Song M, Connelly JT, Ameer-Beg S, Knight MM and Wheeler AP (2013). "Super-resolution imaging strategies for cell biologists using a spinning disk microscope." Plos One vol. 8 (10)
      01-01-2013

    2012

    • Wann A and Knight M (2012). "A role for IFT88/the primary cilium in the inflammatory response to interleukin-1." Cilia vol. 1 (Suppl 1)
      16-11-2012
    • Hernandez V, Pravincumar P, Diaz-Font A, May-Simera H, Jenkins D, Knight M and Beales P (2012). "Bardet-Biedl syndrome proteins control cilia length through regulation of actin polymerisation." Cilia vol. 1 (Suppl 1)
      16-11-2012
    • Thompson C, Prodromou N, Osborn D, Ashworth R, Knight M, Beales P and Chapple J (2012). "Heat-shock induces rapid resorption of primary cilia." Cilia vol. 1 (Suppl 1), p52-p52.
      16-11-2012
    • Thompson C, Chapple J and Knight M (2012). "Mechanical strain disrupts primary cilia structure and modulates hedgehog signalling in adult chondrocytes." Cilia vol. 1 (Suppl 1), p53-p53.
      16-11-2012
    • Wann A, Zuo N, Haycraft C, Jensen C, Poole C, McGlashan S and Knight M (2012). "The primary cilium conducts chondrocyte mechanotransduction." Cilia vol. 1 (Suppl 1)
      16-11-2012
    • McMurray R and Knight M (2012). "Topographical regulation of primary cilia orientation and length in mesenchymal stem cells." Cilia vol. 1 (Suppl 1)
      16-11-2012
    • Wheeler APS, Morad S, Buchholz N and Knight MM (2012). "The Shape of the Urine Stream - From Biophysics to Diagnostics." Plos One vol. 7 (10)
      16-10-2012
    • Chen J, Irianto J, Inamdar S, Pravincumar P, Lee DA, Bader DL and Knight MM (2012). "Cell mechanics, structure, and function are regulated by the stiffness of the three-dimensional microenvironment." Biophys J vol. 103 (6), 1188-1197.
      19-09-2012
    • Prodromou NV, Thompson CL, Osborn DPS, Cogger KF, Ashworth R, Knight MM, Beales PL and Chapple JP (2012). "Heat shock induces rapid resorption of primary cilia." J Cell Sci vol. 125 (Pt 18), 4297-4305.
      15-09-2012
    • Pravincumar P, Bader DL and Knight MM (2012). "Viscoelastic Cell Mechanics and Actin Remodelling Are Dependent on the Rate of Applied Pressure." Plos One vol. 7 (9)
      11-09-2012
    • Wann AKT and Knight MM (2012). "Primary cilia elongation in response to interleukin-1 mediates the inflammatory response." Cellular and Molecular Life Sciences vol. 69 (17), 2967-2977.
      01-09-2012
    • Bonzani IC, Campbell JJ, Knight MM, Williams A, Lee DA, Bader DL and Stevens MM (2012). "Dynamic compressive strain influences chondrogenic gene expression in human periosteal cells: a case study." J Mech Behav Biomed Mater vol. 11, 72-81.
      01-07-2012
    • Wann AKT, Zuo N, Haycraft CJ, Jensen CG, Poole CA, McGlashan SR and Knight MM (2012). "Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes." Faseb Journal vol. 26 (4), 1663-1671.
      01-04-2012
    • Maeda E, Ye S, Wang W, Bader DL, Knight MM and Lee DA (2012). "Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading." Biomechanics and Modeling in Mechanobiology vol. 11 (3-4), 439-447.
      01-03-2012
    • Gladman SJ, Huang W, Lim SN, Dyall SC, Boddy S, Kang JX, Knight MM, Priestley JV and Michael-Titus AT (2012). "Improved outcome after peripheral nerve injury in mice with increased levels of endogenous Omega-3 polyunsaturated fatty acids." Journal of Neuroscience vol. 32 (2), 563-571.
      11-01-2012
    • Hosny NA, Lee DA and Knight MM (2012). "Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations." J Biomed Opt vol. 17 (1)
      01-01-2012
    • Wann AKT, Thompson C and Knight MM (2012). "The role of the primary cilium in chondrocyte response to mechanical loading." In Mechanically Gated Channels and Their Regulation 405-426.
      01-01-2012

    2011

    • Gladman S, Lim SN, Dyall S, Knight MM, Priestley JV and Michael-Titus AT (2011). "Omega-3 fatty acids and acute neurological trauma: A perspective on clinical translation." Ocl - Oleagineux Corps Gras Lipides vol. 18 (6), 317-323.
      01-11-2011
    • Maeda E, Ye S, Wang W, Bader DL, Knight MM and Lee DA (2011). "Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading." Biomechanics and Modeling in Mechanobiology, 1-9.
      01-01-2011
    • Lee DA, Knight MM, Campbell JJ and Bader DL (2011). "Stem cell mechanobiology." J Cell Biochem vol. 112 (1), 1-9.
      01-01-2011

    2010

    • Gladman SJ, Ward RE, Michael-Titus AT, Knight MM and Priestley JV (2010). "The effect of mechanical strain or hypoxia on cell death in subpopulations of rat dorsal root ganglion neurons in vitro." Neuroscience vol. 171 (2), 577-587.
      01-12-2010
    • Vaughan NM, Grainger J, Bader DL and Knight MM (2010). "The potential of pulsed low intensity ultrasound to stimulate chondrocytes matrix synthesis in agarose and monolayer cultures." Medical and Biological Engineering and Computing vol. 48 (12), 1215-1222.
      01-12-2010
    • Wann AKT, Mistry J, Blain EJ, Michael-Titus AT and Knight MM (2010). "Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1β-mediated cartilage degradation." Arthritis Research and Therapy vol. 12 (6)
      08-11-2010
    • Heywood HK, Knight MM and Lee DA (2010). "Both superficial and deep zone articular chondrocyte subpopulations exhibit the crabtree effect but have different basal oxygen consumption rates." Journal of Cellular Physiology vol. 223 (3), 630-639.
      01-06-2010
    • Garcia M and Knight MM (2010). "Cyclic loading opens hemichannels to release ATP as part of a chondrocyte mechanotransduction pathway." Journal of Orthopaedic Research vol. 28 (4), 510-515.
      01-04-2010
    • Maeda E, Ye S, Knight M, Wang W, Bader D and Lee D (2010). "1P338 1J1450 Mechano-regulation of gap junction communications between tenocytes within isolated fascicles(Bioengineering,Oral Presentations,The 48th Annual Meeting of the Biophysical Society of Japan)." Seibutsu Butsuri vol. 50 (supplement2)
      01-01-2010
    • Bader DL and Knight MM (2010). "4 Measuring the biomechanical properties of cartilage cells." In Regenerative Medicine and Biomaterials For The Repair of Connective Tissues 106-136.
      01-01-2010
    • Archer C, Ralphs J, Säämänen A-M, Arokoski JPA, Jurvelin JS, Kiviranta I, Hinz B, Hunziker EB, Bader DL, Knight MM, Dell’accio F, Vincent TL, Aigner T, Schmitz N, Söder S, McIlwraith CW, Hangody L, Kish G, Koreny T, Hangody LR, Módis L, Brittberg M, Sato M, Andriamanalijaona R, Li H, Elisseeff JH, Trice ME, Benjamin M, Kjær M and Magnusson SP (2010). "Contributor contact details." In Regenerative Medicine and Biomaterials For The Repair of Connective Tissues xiii-xvii.
      01-01-2010
    • Bader DL and Knight MM (2010). "Measuring the biomechanical properties of cartilage cells."
      01-01-2010
    • McGlashan SR, Knight MM, Chowdhury TT, Joshi P, Jensen CG, Kennedy S and Poole CA (2010). "Mechanical loading modulates chondrocyte primary cilia incidence and length." Cell Biology International vol. 34 (5), 441-446.
      01-01-2010

    2009

    • Knight MM, Mcglashan SR, Garcia M, Jensen CG and Poole CA (2009). "Articular chondrocytes express connexin 43 hemichannels and P2 receptors - A putative mechanoreceptor complex involving the primary cilium?" Journal of Anatomy vol. 214 (2), 275-283.
      05-02-2009

    2008

    • Bader DL and Knight MM (2008). "Biomechanical analysis of structural deformation in living cells." Medical and Biological Engineering and Computing vol. 46 (10), 951-963.
      27-08-2008

    2007

    • Campbell JJ and Knight MM (2007). "An improved confocal FRAP technique for the measurement of long-term actin dynamics in individual stress fibers." Microscopy Research and Technique vol. 70 (12), 1034-1040.
      01-12-2007
    • Campbell JJ, Blain EJ, Chowdhury TT and Knight MM (2007). "Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes." Biochemical and Biophysical Research Communications vol. 361 (2), 329-334.
      21-09-2007
    • KNIGHT MM, Chowdhury TT, Campbell JJ and Blain EJ (2007). "Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes." Biochemical and Biophysical Research Communications vol. 361 (21), 329-334.
      01-09-2007

    2006

    • Chowdhury TT and Knight MM (2006). "Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression." Journal of Cellular Physiology vol. 209 (3), 845-853.
      01-12-2006
    • Pingguan-Murphy B, El-Azzeh M, Bader DL and Knight MM (2006). "Cyclic compression of chondrocytes modulates a purinergic calcium signalling pathway in a strain rate- and frequency-dependent manner." Journal of Cellular Physiology vol. 209 (2), 389-397.
      01-11-2006
    • Bomzon Z, Knight MM, Bader DL and Kimmel E (2006). "Mitochondrial dynamics in chondrocytes and their connection to the mechanical properties of the cytoplasm." Journal of Biomechanical Engineering vol. 128 (5), 674-679.
      01-10-2006
    • Hakimi O, Knight DP, Knight MM, Grahn MF and Vadgama P (2006). "Ultrastructure of insect and spider cocoon silks." Biomacromolecules vol. 7 (10), 2901-2908.
      01-10-2006
    • Ohashi T, Hagiwara M, Bader DL and Knight MM (2006). "Intracellular mechanics and mechanotransduction associated with chondrocyte deformation during pipette aspiration." Biorheology vol. 43 (3-4), 201-214.

      18-08-2006
    • Knight MM, Bomzon Z, Kimmel E, Sharma AM, Lee DA and Bader DL (2006). "Chondrocyte deformation induces mitochondrial distortion and heterogeneous intracellular strain fields." Biomech Model Mechan vol. 5 (2-3), 180-191.
      01-06-2006
    • Bader DL, Lee DA and Knight MM (2006). "Chondrocyte Deformation and Mechanotransduction in Cartilage Model Systems(International Workshop 2)." The Proceedings of The Bioengineering Conference Annual Meeting of Bed/Jsme vol. 2005.18, 2-3.
      01-01-2006
    • Knight MM, Toyoda T, Lee DA and Bader DL (2006). "Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose." J Biomech vol. 39 (8), 1547-1551.
      01-01-2006

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