Prof David Lee
BSc (Hons), MA, PhD
All Publications
Page 1 of 5
2022
- Modulation of sirtuins during monolayer chondrocyte culture influences cartilage regeneration upon transfer to a 3D culture environment
Heywood HK, Thorpe SD, Jeropoulos RM, Caton PW, Lee DA
Frontiers in Bioengineering and Biotechnology, Frontiers Media Sa vol. 10
06-12-2022 - Oscillations of the circadian clock protein, BMAL-1, align to daily cycles of mechanical stimuli: a novel means to integrate biological time within predictive in vitro model systems
Heywood HK, Gardner L, Knight MM, Lee DA
In Vitro Models, Springer Science and Business Media Llc vol. 1 (6), 405-412.
31-08-2022 - Covariation of Pluripotency Markers and Biomechanical Properties in Mouse Embryonic Stem Cells
Brookes O, Thorpe SD, Rigby Evans O, Keeling MC, Lee DA
Frontiers in Cell and Developmental Biology, Frontiers Media Sa vol. 10
16-05-2022
2020
- G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell Polarization
Lachowski D, Cortes E, Matellan C, Rice A, Lee DA, Thorpe SD, del Río Hernández AE
Frontiers in Cell and Developmental Biology, Frontiers Media Sa vol. 8
22-10-2020 - GPER Activation Inhibits Cancer Cell Mechanotransduction and Basement Membrane Invasion via RhoA
Rice A, Cortes E, Lachowski D, Oertle P, Matellan C, Thorpe SD, Ghose R, Wang H et al.
Cancers, Mdpi Ag vol. 12 (2), 289-289.
25-01-2020 - Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway
Chronopoulos A, Thorpe SD, Cortes E, Lachowski D, Rice AJ, Mykuliak VV, Róg T, Lee DA et al.
Nature Materials, Springer Science and Business Media Llc vol. 19 (6), 669-678.
06-01-2020
2018
- Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor
Cortes E, Lachowski D, Rice A, Thorpe SD, Robinson B, Yeldag G, Lee DA, Ghemtio L et al.
Oncogene, Springer Science and Business Media Llc vol. 38 (16), 2910-2922.
21-12-2018 - Retinoic Acid Receptor‐β Is Downregulated in Hepatocellular Carcinoma and Cirrhosis and Its Expression Inhibits Myosin‐Driven Activation and Durotaxis in Hepatic Stellate Cells
Cortes E, Lachowski D, Rice A, Chronopoulos A, Robinson B, Thorpe S, Lee DA, Possamai LA et al.
Hepatology, Ovid Technologies (Wolters Kluwer Health) vol. 69 (2), 785-802.
17-12-2018 - Tamoxifen mechanically reprograms the tumor microenvironment via\n
HIF \n ‐1A and reduces cancer cell survival
Cortes E, Lachowski D, Robinson B, Sarper M, Teppo JS, Thorpe SD, Lieberthal TJ, Iwamoto K et al.
Embo Reports, Springer Science and Business Media Llc vol. 20 (1)
12-12-2018 - GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment
Cortes E, Sarper M, Robinson B, Lachowski D, Chronopoulos A, Thorpe SD, Lee DA, del Río Hernández AE
Embo Reports, Springer Science and Business Media Llc vol. 20 (1)
11-12-2018
2017
- Development of a two-stage gene selection method that incorporates a novel hybrid approach using the cuckoo optimization algorithm and harmony search for cancer classification
Elyasigomari V, Lee DA, Screen HRC, SHAHEED MH
Journal of Biomedical Informatics vol. 67 (2017), 11-20.
03-02-2017 - Dynamic regulation of nuclear architecture and mechanics—a rheostatic role for the nucleus in tailoring cellular mechanosensitivity
Thorpe SD, Lee DA
Nucleus, Informa Uk Limited vol. 8 (3), 287-300.
02-02-2017
2016
- Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity
Heo S-J, Driscoll TP, Thorpe SD, Nerurkar NL, Baker BM, Yang MT, Chen CS, Lee DA et al.
Elife, Elife Sciences Publications, Ltd vol. 5
30-11-2016 - Oxygen tension modulates the effects of TNFα in compressed chondrocytes
Tilwani RK, Vessillier S, Pingguan-Murphy B, Lee DA, Bader DL, Chowdhury TT
Inflammation Research, Springer Science and Business Media Llc vol. 66 (1), 49-58.
22-09-2016 - Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells
Heo S-J, Han WM, Szczesny SE, Cosgrove BD, Elliott DM, Lee DA, Duncan RL, Mauck RL
Biophysical Journal, Elsevier Bv vol. 111 (4), 864-874.
01-08-2016 - Chondrocyte dedifferentiation increases cell stiffness by strengthening membrane-actin adhesion
Sliogeryte K, Botto L, Lee DA, Knight MM
Osteoarthritis and Cartilage, Elsevier Bv vol. 24 (5), 912-920.
01-05-2016 - States rights and Australia’s adoption of the statute of Westminster, 1931–1942
Lee D
History Australia, Informa Uk Limited vol. 13 (2), 258-274.
02-04-2016 - Bioenergetic reprogramming of articular chondrocytes by exposure to exogenous and endogenous reactive oxygen species and its role in the anabolic response to low oxygen
Heywood HK, Lee DA
Journal of Tissue Engineering and Regenerative Medicine, Wiley vol. 11 (8), 2286-2294.
22-01-2016 - Type VI Collagen Regulates Dermal Matrix Assembly and Fibroblast Motility
Theocharidis G, Drymoussi Z, Kao AP, Barber AH, Lee DA, Braun KM, Connelly JT
Journal of Investigative Dermatology vol. 136 (1), 74-83.
01-01-2016
2015
- Biophysical Regulation of Chromatin Architecture Instills a Mechanical Memory in Mesenchymal Stem Cells
Heo S-J, Thorpe SD, Driscoll TP, Duncan RL, Lee DA, Mauck RL
Scientific Reports, Springer Science and Business Media Llc vol. 5 (1)
23-11-2015 - FINITE ELEMENT ANALYSIS OF MECHANICAL DEFORMATION OF CHONDROCYTE TO 2D SUBSTRATE AND 3D SCAFFOLD
CHEN J, BADER DL, LEE DA, KNIGHT MM
Journal of Mechanics in Medicine and Biology, World Scientific Pub Co Pte Lt vol. 15 (05), 1550077-1550077.
01-10-2015 - Verket som ble borte – ekfrase som dokumentasjon for ettertiden
Grøttum I, Nødseth IL
Ekfrase, Scandinavian University Press / Universitetsforlaget As vol. 6 (01), 50-54.
11-05-2015
2014
- Stem cell differentiation increases membrane-actin adhesion regulating cell blebability, migration and mechanics
Sliogeryte K, Thorpe SD, Lee DA, Botto L, Knight MM
Scientific Reports, Springer Science and Business Media Llc vol. 4 (1)
04-12-2014 - Quantification of chromatin condensation level by image processing
Irianto J, Lee DA, Knight MM
Medical Engineering &Amp; Physics, Elsevier Bv vol. 36 (3), 412-417.
01-03-2014 - Culture Expansion in Low-Glucose Conditions Preserves Chondrocyte Differentiation and Enhances Their Subsequent Capacity to Form Cartilage Tissue in Three-Dimensional Culture
Heywood HK, Nalesso G, Lee DA, Dell'Accio F
Bioresearch Open Access, Mary Ann Liebert Inc vol. 3 (1), 9-18.
01-02-2014
2013
- Osmotic Challenge Drives Rapid and Reversible Chromatin Condensation in Chondrocytes
Irianto J, Swift J, Martins RP, McPhail GD, Knight MM, Discher DE, Lee DA
Biophysical Journal, Elsevier Bv vol. 104 (4), 759-769.
01-02-2013 - Continuous and Uninterrupted Oxygen Tension Influences the Colony Formation and Oxidative Metabolism of Human Mesenchymal Stem Cells
Pattappa G, Thorpe SD, Jegard NC, Heywood HK, de Bruijn JD, Lee DA
Tissue Engineering Part C: Methods, Mary Ann Liebert Inc vol. 19 (1), 68-79.
01-01-2013 - Reluctant relaxation
Lee D
History Australia, Informa Uk Limited vol. 10 (3), 149-170.
01-01-2013
2012
- New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures
Sillitoe I, Cuff AL, Dessailly BH, Dawson NL, Furnham N, Lee D, Lees JG, Lewis TE et al.
Nucleic Acids Research, Oxford University Press (Oup) vol. 41 (D1), D490-D498.
29-11-2012 - Cell Mechanics, Structure, and Function Are Regulated by the Stiffness of the Three-Dimensional Microenvironment
Chen J, Irianto J, Inamdar S, Pravincumar P, Lee DA, Bader DL, Knight MM
Biophysical Journal, Elsevier Bv vol. 103 (6), 1188-1197.
01-09-2012 - Mechanical Regulation of Nuclear Structure and Function
Martins RP, Finan JD, Farshid G, Lee DA
Annual Review of Biomedical Engineering, Annual Reviews vol. 14 (1), 431-455.
15-08-2012 - Dynamic compressive strain influences chondrogenic gene expression in human periosteal cells: A case study
Bonzani IC, Campbell JJ, Knight MM, Williams A, Lee DA, Bader DL, Stevens MM
Journal of The Mechanical Behavior of Biomedical Materials, Elsevier Bv vol. 11, 72-81.
01-07-2012 - Improving metabolic flux predictions using absolute gene expression data
Lee D, Smallbone K, Dunn WB, Murabito E, Winder CL, Kell DB, Mendes P, Swainston N
Bmc Systems Biology, Springer Science and Business Media Llc vol. 6 (1)
19-06-2012 - Stanley Melbourne Bruce in London, 1938–41
Lee D
The Journal of Imperial and Commonwealth History, Informa Uk Limited vol. 40 (1), 45-65.
01-03-2012 - Scaling and mesostructure of Carbopol dispersions
Gutowski IA, Lee D, de Bruyn JR, Frisken BJ
Rheologica Acta, Springer Science and Business Media Llc vol. 51 (5), 441-450.
18-01-2012 - Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading
Maeda E, Ye S, Wang W, Bader DL, Knight MM, Lee DA
Biomechanics and Modeling in Mechanobiology vol. 11 (3-4), 439-447.
01-01-2012 - Single photon counting fluorescence lifetime detection of pericellular oxygen concentrations
Hosny NA, Lee DA, Knight MM
Journal of Biomedical Optics, Spie-Intl Soc Optical Eng vol. 17 (1), 016007-016007.
01-01-2012 - White Globules in Melanocytic Neoplasms: In Vivo and Ex Vivo Characteristics
Jaimes N, Scope A, Welzel J, Wang KX, Lee DA, Siegel DM, Marghoob AA
Dermatologic Surgery, Ovid Technologies (Wolters Kluwer Health) vol. 38 (1), 128-132.
01-01-2012
2011
- The mechanics of flexor tendon adhesions
Branford OA, Lee DA, Bader DL, Grobbelaar AO
Journal of Hand Surgery (European Volume), Sage Publications vol. 37 (6), 555-563.
14-12-2011 - The attachment of intrinsic and extrinsic, mobilized and immobilized adhesion cells to collagen and fibronectin
Branford OA, Lee DA, Rolfe KJ, Grobbelaar AO
Journal of Hand Surgery (European Volume), Sage Publications vol. 37 (6), 564-572.
17-11-2011 - Extensive oral herpes simplex virus type 1 infection in a haematopoietic stem cell transplant recipient not responding to aciclovir
Moses SE, Osborne W, Valappil M, Collin M, Lee D, Waugh S, Jackson G, Parry CM et al.
Journal of Clinical Virology, Elsevier Bv vol. 52 (2), 67-69.
01-10-2011 - The Metabolism of Human Mesenchymal Stem Cells During Proliferation and Differentiation
Pattappa G, Heywood HK, De Bruijn JD, Lee DA
J Cell Physiol vol. 226 (10), 2562-2570.
01-10-2011 - The metabolism of human mesenchymal stem cells during proliferation and differentiation.
Pattappa G, Heywood HK, de Bruijn JD, Lee DA
Journal of Cellular Physiology vol. 226 (10), 2562-2570.
01-10-2011 - Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment.
Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH, Screen HRC
Proc Inst Mech Eng H vol. 225 (8), 821-830.
01-08-2011 - Gap junction permeability between tenocytes within tendon fascicles is suppressed by tensile loading
Maeda E, Ye S, Wang W, Bader DL, Knight MM, Lee DA
Biomechanics and Modeling in Mechanobiology, Springer Science and Business Media Llc vol. 11 (3-4), 439-447.
25-06-2011 - Investigating the microstructure of a yield-stress fluid by light scattering
Lee D, Gutowski IA, Bailey AE, Rubatat L, de Bruyn JR, Frisken BJ
Physical Review E, American Physical Society (Aps) vol. 83 (3)
10-03-2011 - 1,000 structures and more from the MCSG
Lee D, de Beer TAP, Laskowski RA, Thornton JM, Orengo CA
Bmc Structural Biology, Springer Science and Business Media Llc vol. 11 (1), 2-2.
01-01-2011 - Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment
Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH, Screen HRC
P I Mech Eng H vol. 225 (H8), 821-830.
01-01-2011 - Electrospray deposited fibronectin retains the ability to promote cell adhesion
Martyn SV, Heywood HK, Rockett P, Paine MD, Wang MJ, Dobson PJ, Sheard SJ, Lee DA et al.
J Biomed Mater Res B vol. 96B (1), 110-118.
01-01-2011 - Novel devices for diagnosis and treatment
Lee DA, Siegel DM
Journal of Drugs in Dermatology vol. 10 (1), 21-22.
01-01-2011