Prof Martin Knight
BEng, MSc, PhD, FHEA

 

Current Funding

  • Micro-manufacturing of tissue patterned organ-chips for accelerated deployment of new medicines
    Martin Knight, Hazel Screen, Julien Gautrot, Timothy Hopkins, John Connelly, Liisa Blowes and Xavier Griffin
    £1,787,725 EPSRC Engineering and Physical Sciences Research Council 
    Grant Summary

    01-10-2024 - 30-09-2027
  • EPSRC Centre for Doctoral Training in Next Generation Organ-on-a-Chip Technology (COaCT)
    Hazel Screen, Martin Knight, Thomas Iskratsch, Caroline Roney, Yi Sui, David Lee, Julia Shelton, Zion Tse, John Connelly, Adrian Biddle and Lucy Norling
    £7,066,811 EPSRC Engineering and Physical Sciences Research Council 
    Grant Summary

    01-07-2024 - 30-09-2032
  • Development of an Organ-on-a-chip model of polycystic kidney disease using CRISPR modified human kidney cell line
    Martin Knight and Cleo Bishop
    £39,986 Kidney Research UK 
    Grant Summary

    01-12-2023 - 30-11-2025
  • Epithelial Exchange Surfaces – From organizing principles to novel culture models of the gatekeepers of the body
    Martin Knight, Hazel Screen, Wen Wang, Clare Thompson and Cleo Bishop
    £260,676 EPSRC - EU Scheme 
    Grant Summary

    01-12-2023 - 30-11-2027
  • Precision Musculoskeletal Care
    John Whiteley, Costantino Pitzalis, Martin Knight, Gregory Slabaugh and Xavier Griffin
    £3,343,542 National Institute for Health Research
    01-12-2022 - 30-11-2027
  • Incorporating physical cues in organ-chip models
    Hazel Screen and Martin Knight
    £20,000 Emulate Inc.
    01-10-2022 - 30-09-2026
  • Human synovium-cartilage organ-chip for personalised surgical screening
    Martin Knight and Timothy Hopkins
    £311,203 Versus Arthritis
    01-04-2022 - 30-06-2026
  • Organ-on-a-chip Centre of Excellence
    Martin Knight and Hazel Screen
    £420,794 Emulate Inc.
    20-08-2019 - 01-10-2029

Recent Funding

  • Organ-chip Facility: A world-class in vitro models facility for the UK community, reducing the barriers to adoption to drive animal replacement
    Hazel Screen, Stefaan Verbruggen, Martin Knight, Julia Shelton, Timothy Hopkins and John Connelly
    £573,537 NC3Rs National Centre for the Replacement, Refinement and Reduction of Animals in Research 
    Grant Summary

    07-10-2024 - 14-03-2025
  • Production of a Human Growth Plate Organ-Chip Model of Skeletal Development
    Martin Knight, Clare Thompson and Hazel Screen
    £197,923 BBSRC Biotechnology and Biological Sciences Research Council
    01-02-2023 - 31-07-2024
  • Highthroughput Light Sheet Microscopy: Imaging Across Scales
    Viji Draviam Sastry, Caroline Brennan, Vidya Darbari, Jose Martin Duran, Ivan Kadurin, Maria Isabel Palacios De Castro, Richard Pickersgill, Sarah McClelland, Tyson Sharp and Martin Knight
    £386,205 MRC Medical Research Council
    01-10-2022 - 31-03-2023
  • Correlating structural and proteomic techniques on cartilage
    Himadri Gupta and Martin Knight
    £18,515 MRC Medical Research Council
    24-07-2022 - 28-02-2023
  • Emulate Organs-on-Chips Centre Technician
    Martin Knight, Hazel Screen and Clare Thompson
    £49,584 Emulate Inc.
    01-01-2021 - 31-12-2023
  • Organ-on-a-chip model of breast cancer bone metastases
    Martin Knight and Oliver Pearce
    £268,711 CR-UK Cancer Research UK
    01-01-2021 - 30-06-2024
  • MICA: Organ-on-a-chip models for safety testing of regenerative medicine products
    Hazel Screen and Martin Knight
    £473,325 MRC Medical Research Council
    24-08-2020 - 24-05-2024
  • EPSRC Core Equipment Call
    Wen Wang, Martin Knight, Clive Parini and Isaac Abrahams
    £125,000 EPSRC Engineering and Physical Sciences Research Council
    13-02-2020 - 12-08-2021
  • Does the biological clock within cartilage align to diurnal patterns in activity?
    David Lee, Hannah Heywood and Martin Knight
    £9,954 EPSRC Engineering and Physical Sciences Research Council
    01-10-2019 - 31-10-2020
  • Pharmaceutical modulation of cilia expression
    Martin Knight
    £3,000 Royal College of Surgeons
    07-05-2019 - 07-11-2019
  • Organ-on-a-chip technologies
    Hazel Screen and Martin Knight
    £479,339 Medical Research Council
    01-08-2018 - 30-09-2022
  • The effect of cobalt ions on primary cilia in bone cells
    Martin Knight and Frances Freer
    £2,500 Royal College of Surgeons
    01-05-2018 - 01-12-2018
  • META-DORM - Mechanobiology of METAstatic and DORMant cancer cells in bone marrow lesions
    Martin Knight
    £152,740 EU Commission - Horizon 2020
    01-01-2018 - 29-06-2020
  • Collagen Fibrillar Network in Ageing Cartilage
    Himadri Gupta and Martin Knight
    £374,874 BBSRC Biotechnology and Biological Sciences Research Council
    01-10-2017 - 24-07-2023
  • Innovation Fund: High-throughput Library Screen
    Martin Knight
    £9,960 BBSRC Biotechnology and Biological Sciences Research Council
    01-09-2016 - 31-08-2018
  • Osteoarthritis May Be Treated as an Environmental Ciliopathy
    Martin Knight
    £365,598 MRC Medical Research Council
    01-09-2014 - 20-03-2020