Prof Martin Knight
BEng, MSc, PhD, FHEA

 

All Publications

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2010

  • Cyclic Loading Opens Hemichannels to Release ATP as Part of a Chondrocyte Mechanotransduction Pathway
    Garcia M, Knight MM
    J Orthop Res vol. 28 (4), 510-515.  
    01-04-2010
  • 1P338 1J1450 Mechano-regulation of gap junction communications between tenocytes within isolated fascicles(Bioengineering,Oral Presentations,The 48th Annual Meeting of the Biophysical Society of Japan)
    Maeda E, Ye S, Knight M, Wang W, Bader D, Lee D
    Seibutsu Butsuri, Biophysical Society of Japan vol. 50 (supplement2) 
    01-01-2010
  • A compartment model to evaluate the permeability of gap junctions between tenocytes in tendon fascicles
    Ye S, Maeda E, Knight M, Lee D, Bader D, Wang W
    Faseb Journal vol. 24 
    01-01-2010
  • Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1 beta-mediated cartilage degradation
    Wann AKT, Mistry J, Blain EJ, Michael-Titus AT, Knight MM
    Arthritis Res Ther vol. 12 (6) 
    01-01-2010
  • Measuring the biomechanical properties of cartilage cells
    Bader DL, Knight MM
    , Elsevier, 106-136.  
    01-01-2010

2009

  • Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium?
    Knight MM, McGlashan SR, Garcia M, Jensen CG, Poole CA
    J Anat vol. 214 (2), 275-283.  
    01-02-2009

2008

  • Biomechanical analysis of structural deformation in living cells
    Bader DL, Knight MM
    Med Biol Eng Comput vol. 46 (10), 951-963.  
    01-10-2008

2007

  • An improved confocal FRAP technique for the measurement of long-term actin dynamics in individual stress fibers
    Campbell JJ, Knight MM
    Microsc Res Techniq vol. 70 (12), 1034-1040.  
    01-12-2007
  • Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes
    Campbell JJ, Blain EJ, Chowdhury TT, Knight MM
    Biochem Bioph Res Co vol. 361 (2), 329-334.  
    21-09-2007
  • Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes
    KNIGHT MM, Chowdhury TT, Campbell JJ, Blain EJ
    Biochemical and Biophysical Research Communications vol. 361 (21), 329-334.  
    01-09-2007

2006

  • Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression
    Chowdhury TT, Knight MM
    J Cell Physiol vol. 209 (3), 845-853.  
    01-12-2006
  • Cyclic compression of chondrocytes modulates a purinergic calcium signalling pathway in a strain rate- and frequency-dependent manner
    Pingguan-Murphy B, El-Azzeh M, Bader DL, Knight MM
    J Cell Physiol vol. 209 (2), 389-397.  
    01-11-2006
  • Ultrastructure of insect and spider cocoon silks
    Hakimi O, Knight DP, Knight MM, Grahn MF, Vadgama P
    Biomacromolecules vol. 7 (10), 2901-2908.  
    09-10-2006
  • Mitochondrial dynamics in chondrocytes and their connection to the mechanical properties of the cytoplasm
    Bomzon Z, Knight MM, Bader DL, Kimmel E
    J Biomech Eng-T Asme vol. 128 (5), 674-679.  
    01-10-2006
  • Chondrocyte Deformation Induces Mitochondrial Distortion and Heterogeneous Intracellular Strain Fields
    Knight MM, Bomzon Z, Kimmel E, Sharma AM, Lee DA, Bader DL
    Biomechanics and Modeling in Mechanobiology, Springer Science and Business Media Llc vol. 5 (2-3), 180-191.  
    07-03-2006
  • Chondrocyte Deformation and Mechanotransduction in Cartilage Model Systems(International Workshop 2)
    Bader DL, Lee DA, Knight MM
    The Proceedings of The Bioengineering Conference Annual Meeting of Bed/Jsme, Japan Society of Mechanical Engineers vol. 2005.18, 2-3.  
    01-01-2006
  • Intracellular mechanics and mechanotransduction associated with chondrocyte deformation during pipette aspiration
    Ohashi T, Hagiwara M, Bader DL, Knight MM
    Biorheology vol. 43 (3-4), 201-214.  
    01-01-2006
  • Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose
    Knight MM, Toyoda T, Lee DA, Bader DL
    J Biomech vol. 39 (8), 1547-1551.  
    01-01-2006
  • Probing mechanical heterogeneity in chondrocytes using passive microtheology
    Bomzon Z, Knight MM, Bader DL, Kimmel E
    Journal of Biomechanics, Elsevier Bv vol. 39, S230-S230.  
    01-01-2006

2005

  • Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles
    Pingguan-Murphy B, Lee DA, Bader DL, Knight MM
    Arch Biochem Biophys vol. 444 (1), 45-51.  
    01-12-2005

2004

  • Confocal analysis of local and cellular strains in chondrocyte-agarose constructs subjected to mechanical shear.
    Sawae Y, Shelton JC, Bader DL, Knight MM
    Ann Biomed Eng vol. 32 (6), 860-870.  
    01-06-2004
  • Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage
    Holloway I, Kayser M, Lee DA, Bader DL, Bentley G, Knight MM
    Osteoarthr Cartilage vol. 12 (1), 17-24.  
    01-01-2004

2003

  • Live cell imaging using confocal microscopy induces intracellular calcium transients and cell death
    Knight MM, Roberts SR, Lee DA, Bader DL
    Am J Physiol-Cell Ph vol. 284 (4), C1083-C1089.  
    01-04-2003
  • Confocal Analysis of Local and Cellular Strains in Chondrocyte - Agarose Constructs Subjected to Shear.
    Bader DL, SHELTON JC, Knight MM, Sawae Y
    J Biochemical Engineering Asme 
    01-01-2003

2002

  • Cell and nucleus deformation in compressed chondrocyte-alginate constructs: temporal changes and calculation of cell modulus
    Knight MM, Bravenboer JVDB, Lee DA, van Osch GJVM, Weinans H, Bader DL
    Bba-Gen Subjects vol. 1570 (1), 1-8.  
    15-02-2002

2001

  • Chondrocyte deformation within mechanically and enzymatically extracted chondrons compressed in agarose
    Knight MM, Ross JM, Sherwin AF, Lee DA, Bader DL, Poole CA
    Bba-Gen Subjects vol. 1526 (2), 141-146.  
    03-05-2001
  • Temporal changes in cytoskeletal organisation within isolated chondrocytes quantified using a novel image analysis technique
    Knight MM, Idowu BD, Lee DA, Bader DL
    Med Biol Eng Comput vol. 39 (3), 397-404.  
    01-05-2001
  • Mechanical compression influences intracellular Ca2+ signaling in chondrocytes seeded in agarose constructs
    Roberts SR, Knight MM, Lee DA, Bader DL
    J Appl Physiol vol. 90 (4), 1385-1391.  
    01-04-2001
  • Compressive deformation and damage of muscle cell subpopulations in a model system
    Bouten CVC, Knight MM, Lee DA, Bader DL
    Ann Biomed Eng vol. 29 (2), 153-163.  
    01-02-2001

2000

  • Beta transition and stress-induced phase separation in the spinning of spider dragline silk
    Knight DP, Knight MM, Vollrath F
    Int J Biol Macromol vol. 27 (3), 205-210.  
    13-06-2000
  • Confocal analysis of cytoskeletal organisation within isolated chondrocyte sub-populations cultured in agarose
    Idowu BD, Knight MM, Bader DL, Lee DA
    Histochem J vol. 32 (3), 165-174.  
    01-03-2000
  • Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels
    Lee DA, Knight MM, Bolton JF, Idowu BD, Kayser MV, Bader DL
    J Biomech vol. 33 (1), 81-95.  
    01-01-2000

1998

  • Measurement of the deformation of isolated chondrocytes in agarose subjected to cyclic compression
    Knight MM, Ghori SA, Lee DA, Bader DL
    Med Eng Phys vol. 20 (9), 684-688.  
    01-11-1998
  • Response of chondrocyte subpopulations cultured within unloaded and loaded agarose
    Lee DA, Noguchi T, Knight MM, O'Donnell L, Bentley G, Bader DL
    J Orthop Res vol. 16 (6), 726-733.  
    01-11-1998
  • The influence of elaborated pericellular matrix on the deformation of isolated articular chondrocytes cultured in agarose
    Knight MM, Lee DA, Bader DL
    Bba-Mol Cell Res vol. 1405 (1-3), 67-77.  
    21-10-1998

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