Prof Martin Knight
BEng, MSc, PhD, FHEA

 

All Publications

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2010

2009

  • Articular chondrocytes express connexin 43 hemichannels and P2 receptors - A putative mechanoreceptor complex involving the primary cilium?
    Knight MM, Mcglashan SR, Garcia M, Jensen CG and Poole CA
    Journal of Anatomy vol. 214 (2), 275-283.  
    05-02-2009

2008

  • Biomechanical analysis of structural deformation in living cells
    Bader DL and Knight MM
    Medical and Biological Engineering and Computing vol. 46 (10), 951-963.  
    27-08-2008

2007

  • Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes
    Campbell JJ, Blain EJ, Chowdhury TT and Knight MM
    Biochemical and Biophysical Research Communications vol. 361 (2), 329-334.  
    21-09-2007
  • Loading alters actin dynamics and up-regulates cofilin gene expression in chondrocytes
    KNIGHT MM, Chowdhury TT, Campbell JJ and Blain EJ
    Biochemical and Biophysical Research Communications vol. 361 (21), 329-334.  
    01-09-2007
  • An improved confocal FRAP technique for the measurement of long-term actin dynamics in individual stress fibers
    Campbell JJ and Knight MM
    Microscopy Research and Technique vol. 70 (12), 1034-1040.  
    01-01-2007

2006

  • Purinergic pathway suppresses the release of NO and stimulates proteoglycan synthesis in chondrocyte/agarose constructs subjected to dynamic compression
    Chowdhury TT and Knight MM
    Journal of Cellular Physiology vol. 209 (3), 845-853.  
    01-12-2006
  • Cyclic compression of chondrocytes modulates a purinergic calcium signalling pathway in a strain rate- and frequency-dependent manner
    Pingguan-Murphy B, El-Azzeh M, Bader DL and Knight MM
    Journal of Cellular Physiology vol. 209 (2), 389-397.  
    01-11-2006
  • Mitochondrial dynamics in chondrocytes and their connection to the mechanical properties of the cytoplasm
    Bomzon Z, Knight MM, Bader DL and Kimmel E
    Journal of Biomechanical Engineering vol. 128 (5), 674-679.  
    01-10-2006
  • Ultrastructure of insect and spider cocoon silks
    Hakimi O, Knight DP, Knight MM, Grahn MF and Vadgama P
    Biomacromolecules vol. 7 (10), 2901-2908.  
    01-10-2006
  • Intracellular mechanics and mechanotransduction associated with chondrocyte deformation during pipette aspiration
    Ohashi T, Hagiwara M, Bader DL and Knight MM
    Biorheology vol. 43 (3-4), 201-214.  
    18-08-2006
  • Chondrocyte deformation induces mitochondrial distortion and heterogeneous intracellular strain fields
    Knight MM, Bomzon Z, Kimmel E, Sharma AM, Lee DA and Bader DL
    Biomech Model Mechan vol. 5 (2-3), 180-191.  
    01-06-2006
  • Chondrocyte Deformation and Mechanotransduction in Cartilage Model Systems(International Workshop 2)
    Bader DL, Lee DA and Knight MM
    The Proceedings of The Bioengineering Conference Annual Meeting of Bed/Jsme, Japan Society of Mechanical Engineers vol. 2005.18, 2-3.  
    01-01-2006
  • Mechanical compression and hydrostatic pressure induce reversible changes in actin cytoskeletal organisation in chondrocytes in agarose.
    Knight MM, Toyoda T, Lee DA and Bader DL
    J Biomech vol. 39 (8), 1547-1551.  
    01-01-2006
  • Probing mechanical heterogeneity in chondrocytes using passive microtheology
    Bomzon Z, Knight MM, Bader DL and Kimmel E
    Journal of Biomechanics, Elsevier vol. 39 
    01-01-2006

2005

  • Activation of chondrocytes calcium signalling by dynamic compression is independent of number of cycles.
    Pingguan-Murphy B, Lee DA, Bader DL and Knight MM
    Arch Biochem Biophys vol. 444 (1), 45-51.  
    01-12-2005

2004

  • Confocal analysis of local and cellular strains in chondrocyte-agarose constructs subjected to mechanical shear.
    Sawae Y, Shelton JC, Bader DL and Knight MM
    Ann Biomed Eng vol. 32 (6), 860-870.  
    01-06-2004
  • Increased presence of cells with multiple elongated processes in osteoarthritic femoral head cartilage.
    Holloway I, Kayser M, Lee DA, Bader DL, Bentley G and Knight MM
    Osteoarthritis Cartilage vol. 12 (1), 17-24.  
    01-01-2004
  • Mechanical loading of chondrocytes embedded in 3D constructs: in vitro methods for assessment of morphological and metabolic response to compressive strain.
    Lee DA and Knight MM
    Methods Mol Med vol. 100, 307-324.  
    01-01-2004

2003

2002

  • Cell and nucleus deformation in compressed chondrocyte-alginate constructs: temporal changes and calculation of cell modulus.
    Knight MM, van de Breevaart Bravenboer J, Lee DA, van Osch GJVM, Weinans H and Bader DL
    Biochim Biophys Acta vol. 1570 (1), 1-8.  
    15-02-2002

2001

  • Chondrocyte deformation within mechanically and enzymatically extracted chondrons compressed in agarose.
    Knight MM, Ross JM, Sherwin AF, Lee DA, Bader DL and Poole CA
    Biochim Biophys Acta vol. 1526 (2), 141-146.  
    03-05-2001
  • Temporal changes in cytoskeletal organisation within isolated chondrocytes quantified using a novel image analysis technique.
    Knight MM, Idowu BD, Lee DA and Bader DL
    Med Biol Eng Comput vol. 39 (3), 397-404.  
    01-05-2001
  • Mechanical compression influences intracellular Ca2+ signaling in chondrocytes seeded in agarose constructs.
    Roberts SR, Knight MM, Lee DA and Bader DL
    J Appl Physiol (1985) vol. 90 (4), 1385-1391.  
    01-04-2001
  • Compressive deformation and damage of muscle cell subpopulations in a model system.
    Bouten CV, Knight MM, Lee DA and Bade DL
    Ann Biomed Eng vol. 29 (2), 153-163.  
    01-02-2001

2000

  • Confocal analysis of cytoskeletal organisation within isolated chondrocyte sub-populations cultured in agarose.
    Idowu BD, Knight MM, Bader DL and Lee DA
    Histochem J vol. 32 (3), 165-174.  
    01-03-2000
  • Beta transition and stress-induced phase separation in the spinning of spider dragline silk
    Knight DP, KNIGHT MM and Vollrath F
    International Journal of Biological Macromolecules vol. 27 (3), 205-210.  
    01-01-2000
  • Chondrocyte deformation within compressed agarose constructs at the cellular and sub-cellular levels.
    Lee DA, Knight MM, Bolton JF, Idowu BD, Kayser MV and Bader DL
    J Biomech vol. 33 (1), 81-95.  
    01-01-2000

1998

  • Response of chondrocyte subpopulations cultured within unloaded and loaded agarose.
    Lee DA, Noguchi T, Knight MM, O'Donnell L, Bentley G and Bader DL
    J Orthop Res vol. 16 (6), 726-733.  
    01-11-1998
  • The influence of elaborated pericellular matrix on the deformation of isolated articular chondrocytes cultured in agarose.
    Knight MM, Lee DA and Bader DL
    Biochim Biophys Acta vol. 1405 (1-3), 67-77.  
    21-10-1998
  • Measurement of the deformation of isolated chondrocytes in agarose subjected to cyclic compression.
    Knight MM, Ghori SA, Lee DA and Bader DL
    Med Eng Phys vol. 20 (9), 684-688.  
    01-01-1998

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