Prof Hazel Screen
BEng MRes PhD(Lond) CEng

 

Key Publications

  • Zamboulis D, Thorpe CT, Ashraf Kharaz Y, Birch HL, Clegg PD and Screen H (2020). "Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix." Elife Sciences Publications Ltd  Elife 
    16-10-2020

All Publications

    2022

    • Candarlioglu PL, Dal Negro G, Hughes D, Balkwill F, Harris K, Screen H, Morgan H, David R, Beken S, Guenat O, Rowan W and Amour A (2022). "Organ-on-a-chip: current gaps and future directions." Biochemical Society Transactions vol. 50 (2), 665-673.
      01-04-2022
    • Tayfur A, Sendil A, Sezik AC, Jean-François K, Sancho I, Le Sant G, Donmez G, Duman M, Tayfur B, Pawson J, Uzlasir S, Miller SC, Screen H and Morrissey D (2022). "Self-reported bio-psycho-social factors partially distinguish patellar tendinopathy from other knee problems and explain severity in jumping athletes: A case–control study." Physiotherapy vol. 114, e105-e106.
      01-02-2022
    • Tayfur A, Zenner D, Miller SC, Screen H and Morrissey D (2022). "Outcome predictors for recovery of patellar tendinopathy in jumping athletes: an international prospective cohort study." Bmj Journals  Bmj Open
      20-01-2022
    • Tayfur A, Haque A, Salles JI, Malliaras P, Screen H and Morrissey D (2022). "Are Landing Patterns in Jumping Athletes Associated with Patellar Tendinopathy? A Systematic Review with Evidence Gap Map and Meta-analysis." Sports Medicine vol. 52 (1), 123-137.
      01-01-2022

    2021

    • Zahradnik TM, Cresswell M, Squier K, Waugh C, Brunham L, Screen H and Scott A (2021). "Can Achilles tendon xanthoma be distinguished from Achilles tendinopathy using Dixon method MRI? A cross-sectional exploratory study." Bmc Musculoskeletal Disorders vol. 22 (1)
      01-12-2021
    • Patel D, Zamboulis DE, Spiesz EM, Birch HL, Clegg PD, Thorpe CT and Screen HRC (2021). "Structure-function specialisation of the interfascicular matrix in the human achilles tendon." Acta Biomaterialia vol. 131, 381-390.
      01-09-2021
    • Squier K, Scott A, Hunt MA, Brunham LR, Wilson DR, Screen H and Waugh CM (2021). "The effects of cholesterol accumulation on Achilles tendon biomechanics: A crosssectional study." Plos One vol. 16 (9 September)
      01-09-2021
    • Waugh C, Mousavizadeh R, Screen H and Scott A (2021). "The Impact of Hypercholesterolemia on Tendon Injury Repair." The Faseb Journal vol. 35 (S1)
      14-05-2021
    • Godinho MSC, Thorpe CT, Greenwald SE and Screen H (2021). "Elastase treatment of tendon specifically impacts the mechanical properties of the interfascicular matrix." Elsevier  Acta Biomaterialia
      26-01-2021
    • Siebert T, Screen HRC and Rode C (2021). "8 Computational modelling of muscle, tendon, and ligaments biomechanics." In Computational Modelling of Biomechanics and Biotribology in The Musculoskeletal System 155-186.
      01-01-2021

    2020

    • Zamboulis D, Thorpe CT, Ashraf Kharaz Y, Birch HL, Clegg PD and Screen H (2020). "Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix." Elife Sciences Publications Ltd  Elife
      16-10-2020
    • Gains C, Correia J, Baan G, Noort W, Screen H and Maas H (2020). "Force Transmission Between the Gastrocnemius and Soleus Sub-Tendons of the Achilles Tendon in Rat." Frontiers Media  Frontiers in Bioengineering and Biotechnology vol. 8, 700-700.
      17-07-2020
    • Shearer T, Parnell WJ, Lynch B, Screen HRC and Abrahams ID (2020). "A recruitment model of tendon viscoelasticity that incorporates fibril creep and explains strain-dependent relaxation." Journal of Biomechanical Engineering vol. 142 (7)
      01-07-2020
    • Tayfur A, Salles JI, Miller SC, Screen H and Morrissey D (2020). "Patellar tendinopathy outcome predictors in jumping athletes: feasibility of measures for a cohort study." Physical Therapy in Sport vol. 44, 75-84.
      01-07-2020

    2019

    • Chineye U, Jones E, Riley G, Morrissey D and Screen H (2019). "An in vitro investigation into the effects of 10Hz cyclic loading on tenocyte metabolism." Wiley  Scandinavian Journal of Medicine and Science in Sports
      18-05-2019
    • Capilnasiu A, Hadjicharalambous M, Fovargue D, Patel D, Holub O, Bilston L, Screen H, Sinkus R and Nordsletten D (2019). "Magnetic resonance elastography in nonlinear viscoelastic materials under load." Biomechanics and Modeling in Mechanobiology vol. 18 (1), 111-135.
      15-02-2019
    • Anssari-Benam A, Screen HRC and Bucchi A (2019). "Insights into the micromechanics of stress-relaxation and creep behaviours in the aortic valve." J Mech Behav Biomed Mater vol. 93, 230-245.
      12-02-2019

    2018

    2017

    • Godinho MSC, Thorpe CT, Greenwald SE and Screen HRC (2017). "Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing." Scientific Reports vol. 7 (1)
      01-12-2017
    • Shearer T, Thorpe CT, Spiesz E and SCREEN HRC (2017). "The relative compliance of energy-storing tendons may be due to the helical fibril arrangement of their fascicles." Royal Society, The  Journal of The Royal Society Interface
      09-08-2017
    • Thorpe CT, Riley GP, Birch HL, Clegg PD and Screen HRC (2017). "Fascicles and the interfascicular matrix show decreased fatigue life with ageing in energy storing tendons." Acta Biomaterialia vol. 56, 58-64.
      01-07-2017
    • BECER CR, Screen HRC, Patel D and Liu R (2017). "A2B-Miktoarm Glycopolymer Fibers and Their Interactions with Tenocytes." American Chemical Society  Bioconjugate Chemistry
      21-06-2017
    • Patel D, Sharma S, Bryant SJ and Screen HRC (2017). "Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response." Advanced Healthcare Materials vol. 6 (4)
      22-02-2017
    • Elyasigomari V, Lee DA, Screen HRC and SHAHEED MH (2017). "Development of a two-stage gene selection method that incorporates a novel hybrid approach using the cuckoo optimization algorithm and harmony search for cancer classification." Journal of Biomedical Informatics vol. 67 (2017), 11-20.
      03-02-2017
    • Anssari-Benam A, Bucchi A, SCREEN HRC and Evans SL (2017). "A transverse isotropic viscoelastic constitutive model for aortic valve tissue." Royal Society, The: Open Access  Royal Society Open Science
      11-01-2017
    • Gupta HS and Screen HRC (2017). "Structural building blocks of soft tissues: Tendons and heart valves." In Cism International Centre For Mechanical Sciences, Courses and Lectures 1-35.
      01-01-2017

    2016

    • Thorpe CT, Riley GP, Birch HL, Clegg PD and Screen HRC (2016). "Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons." Acta Biomaterialia vol. 42, 308-315.
      15-09-2016
    • Handsfield GG, Slane LC and Screen HRC (2016). "Nomenclature of the tendon hierarchy: An overview of inconsistent terminology and a proposed size-based naming scheme with terminology for multi-muscle tendons." Journal of Biomechanics vol. 49 (13), 3122-3124.
      06-09-2016
    • Mozdzen L, Thorpe S, SCREEN HRC and Harley B (2016). "The effect of gradations in mineral content, matrix alignment, and applied strain on human mesenchymal stem cell morphology within collagen biomaterials." Wiley: 12 Months  Advanced Healthcare Materials
      01-06-2016
    • Thorpe CT, Karunaseelan KJ, Ng Chieng Hin J, Riley GP, Birch HL, Clegg PD and Screen HRC (2016). "Distribution of proteins within different compartments of tendon varies according to tendon type." Journal of Anatomy vol. 229 (3), 450-458.
      25-04-2016
    • Rowson D, Knight MM and Screen HRC (2016). "Zonal variation in primary cilia elongation correlates with localized biomechanical degradation in stress deprived tendon." J Orthop Res vol. 34 (12), 2146-2153.
      23-03-2016
    • Chaudhry S, Fernando R, Screen H, Waugh C, Tucker A and Morrissey D (2016). "The use of medical infrared thermography in the detection of tendinopathy: a systematic review." Physical Therapy Reviews vol. 21 (2), 75-82.
      03-03-2016
    • Thorpe CT, Peffers MJ, Simpson D, Halliwell E, Screen HRC and Clegg PD (2016). "Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition." Scientific Reports vol. 6
      04-02-2016
    • Thorpe CT and Screen HRC (2016). "Tendon structure and composition." Advances in Experimental Medicine and Biology vol. 920, 3-10.
      01-01-2016

    2015

    • Thorpe CT, Godinho MSC, Riley GP, Birch HL, Clegg PD and Screen HRC (2015). "The interfascicular matrix enables fascicle sliding and recovery in tendon, and behaves more elastically in energy storing tendons." Journal of The Mechanical Behavior of Biomedical Materials vol. 52, 85-94.
      01-12-2015
    • Thorpe CT, Chaudhry S, Lei II, Varone A, Riley GP, Birch HL, Clegg PD and Screen HRC (2015). "Tendon overload results in alterations in cell shape and increased markers of inflammation and matrix degradation." Scandinavian Journal of Medicine and Science in Sports vol. 25 (4), e381-e391.
      01-08-2015
    • Elyasigomari V, Mirjafari MS, Screen HRC and Shaheed MH (2015). "Cancer classification using a novel gene selection approach by means of shuffling based on data clustering with optimization." Applied Soft Computing Journal vol. 35, 43-51.
      06-07-2015
    • Spiesz EM, Thorpe CT, Chaudhry S, Riley GP, Birch HL, Clegg PD and Screen HRC (2015). "Tendon extracellular matrix damage, degradation and inflammation in response to in vitro overload exercise." Journal of Orthopaedic Research vol. 33 (6), 889-897.
      01-06-2015
    • Screen HRC, Berk DE, Kadler KE, Ramirez F and Young MF (2015). "Tendon functional extracellular matrix." Journal of Orthopaedic Research vol. 33 (6), 793-799.
      01-06-2015
    • Chaudhry S, Morrissey D, Woledge RC, Bader DL and Screen HRC (2015). "Eccentric and concentric exercise of the triceps surae: An in vivo study of dynamic muscle and tendon biomechanical parameters." Journal of Applied Biomechanics vol. 31 (2), 69-78.
      01-04-2015
    • Chaudhry S, Morrissey D, Woledge RC, Bader DL and Screen HRC (2015). "Eccentric and Concentric Exercise of the Triceps Surae: An in Vivo Study of Dynamic Muscle and Tendon Biomechanical Parameters." J Appl Biomech vol. 31 (2), 69-78.
      01-04-2015
    • Thorpe CT, Spiesz EM, Chaudhry S, Screen HRC and Clegg PD (2015). "Science in brief: Recent advances into understanding tendon function and injury risk." Equine Veterinary Journal vol. 47 (2), 137-140.
      01-03-2015
    • Mani-Babu S, Morrissey D, Waugh C, Screen H and Barton C (2015). "The effectiveness of extracorporeal shock wave therapy in lower limb tendinopathy: a systematic review." Am J Sports Med vol. 43 (3), 752-761.
      01-03-2015
    • Thorpe CT, Birch HL, Clegg PD and Screen HRC (2015). "Chapter 1 Tendon Physiology and Mechanical Behavior Structure–Function Relationships." In Tendon Regeneration 3-39.
      01-01-2015
    • Chaudhry S, Morrissey D, Woledge RC, Bader DL and Screen HRC (2015). "Eccentric and concentric exercise of the triceps surae: An in vivo study of dynamic muscle and tendon biomechanical parameters." Journal of Applied Biomechanics vol. 31 (2), 69-78.
      01-01-2015
    • Waugh CM, Morrissey D, Jones E, Riley GP, Langberg H and Screen HRC (2015). "In vivo biological response to extracorporeal shockwave therapy in human tendinopathy." European Cells and Materials vol. 29, 268-280.
      01-01-2015
    • Thorpe CT, Birch HL, Clegg PD and Screen HRC (2015). "Tendon Physiology and Mechanical Behavior: Structure-Function Relationships." In Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes 3-39.
      01-01-2015

    2014

    • Shepherd JH, Riley GP and Screen HRC (2014). "Early stage fatigue damage occurs in bovine tendon fascicles in the absence of changes in mechanics at either the gross or micro-structural level." J Mech Behav Biomed Mater vol. 38, 163-172.
      01-10-2014
    • Peffers MJ, Thorpe CT, Collins JA, Eong R, Wei TKJ, Screen HRC and Clegg PD (2014). "Proteomic analysis reveals age-related changes in tendon matrix composition, with age- and injury-specific matrix fragmentation." J Biol Chem vol. 289 (37), 25867-25878.
      12-09-2014
    • Thorpe C, Peffers M, Simpson D, Halliwell E, Screen H and Clegg P (2014). "104 Characterisation Of The Proteome Of The Tendon Interfascicular Matrix." British Journal of Sports Medicine vol. 48 (Suppl 2), a68-a68.
      05-09-2014
    • Patel D, Bryant S, Riley G, Jones E and Screen H (2014). "78 Human Tenocyte Metabolism Under Pathological And Physiological Loading Conditions." British Journal of Sports Medicine vol. 48 (Suppl 2), a51-a51.
      05-09-2014
    • Rowson D, Knight M and Screen H (2014). "89 Primary Cilia In Tenocytes From The Inter-fascicular Matrix And The Fascicular Matrix." British Journal of Sports Medicine vol. 48 (Suppl 2), a58-a59.
      05-09-2014
    • Spiesz EM, Thorpe CT, Chaudhry S, Riley GP, Birch HL, Clegg PD and Screen HR (2014). "98 Early Inflammatory Response Of Tenocytes To Overload." British Journal of Sports Medicine vol. 48 (Suppl 2), a63-a64.
      05-09-2014
    • Morrissey D, Morton S, Anuj CA and Screen H (2014). "Achillessehnentendinopathie." Sportphysio vol. 02 (03), 105-111.
      20-08-2014
    • Thorpe CT, Riley GP, Birch HL, Clegg PD and Screen HRC (2014). "Effect of fatigue loading on structure and functional behaviour of fascicles from energy-storing tendons." Acta Biomater vol. 10 (7), 3217-3224.
      01-07-2014
    • Waugh C, Jones E, Riley G, Langberg H, Morrissey D and Screen H (2014). "The effects of extracorporeal shockwave therapy on matrix metalloprotease activity in tendinopathy (1046.8)." The Faseb Journal vol. 28 (S1)
      01-04-2014
    • Thorpe CT, Riley GP, Birch HL, Clegg PD and Screen HRC (2014). "Fascicles from energy-storing tendons show an age-specific response to cyclic fatigue loading." Journal of The Royal Society Interface vol. 11 (92)
      06-03-2014
    • Smith R, McIlwraith W, Schweitzer R, Kadler K, Cook J, Caterson B, Dakin S, Heinegard D, Screen H, Stover S, Crevier-Denoix N, Clegg P, Collins M, Little C, Frisbie D, Kjaer M, van Weeren R, Werpy N, Denoix J-M, Carr A, Goldberg A, Bramlage L, Smith M and Nixon A (2014). "Advances in the understanding of tendinopathies: A report on the Second Havemeyer Workshop on equine tendon disease." Equine Veterinary Journal vol. 46 (1), 4-9.
      01-01-2014
    • Shepherd JH, Legerlotz K, Demirci T, Klemt C, Riley GP and Screen HRC (2014). "Functionally distinct tendon fascicles exhibit different creep and stress relaxation behaviour." Proc Inst Mech Eng H vol. 228 (1), 49-59.
      01-01-2014

    2013

    • Shepherd JH and Screen HRC (2013). "Fatigue loading of tendon." Int J Exp Pathol vol. 94 (4), 260-270.
      01-08-2013
    • Thorpe CT, Klemt C, Riley GP, Birch HL, Clegg PD and Screen HRC (2013). "Helical sub-structures in energy-storing tendons provide a possible mechanism for efficient energy storage and return." Acta Biomater vol. 9 (8), 7948-7956.
      01-08-2013
    • Thorpe CT, Birch HL, Clegg PD and Screen HRC (2013). "The role of the non-collagenous matrix in tendon function." Int J Exp Pathol vol. 94 (4), 248-259.
      01-08-2013
    • Legerlotz K, Riley GP and Screen HRC (2013). "GAG depletion increases the stress-relaxation response of tendon fascicles, but does not influence recovery." Acta Biomater vol. 9 (6), 6860-6866.
      01-06-2013
    • Anssari-Benam A, Legerlotz K, Bader DL and Screen HRC (2013). "Response to letter to the editor: End effects in mechanical testing of biomaterials." Journal of Biomechanics vol. 46 (5)
      15-03-2013
    • Legerlotz K, Jones GC, Screen HRC and Riley GP (2013). "Cyclic loading of tendon fascicles using a novel fatigue loading system increases interleukin-6 expression by tenocytes." Scandinavian Journal of Medicine and Science in Sports vol. 23 (1), 31-37.
      01-02-2013
    • Thorpe CT, Udeze CP, Birch HL, Clegg PD and Screen HR (2013). "Capacity for sliding between tendon fascicles decreases with ageing in injury prone equine tendons: a possible mechanism for age-related tendinopathy?" Eur Cell Mater vol. 25, 48-60.
      08-01-2013
    • Thorpe CT, Klemt C, Riley GP, Birch HL, Clegg PD and Screen HRC (2013). "Helical sub-structures in energy-storing tendons provide a possible mechanism for efficient energy storage and return." Acta Biomaterialia vol. 9 (8), 7948-7956.
      01-01-2013
    • Screen HRC, Toorani S and Shelton JC (2013). "Microstructural stress relaxation mechanics in functionally different tendons." Medical Engineering and Physics vol. 35 (1), 96-102.
      01-01-2013
    • Anssari-Benam A, Legerlotz K, Bader DL and Screen HRC (2013). "Response to letter to the editor: End effects in mechanical testing of biomaterials." Journal of Biomechanics
      01-01-2013

    2012

    • Thorpe CT, Udeze CP, Birch HL, Clegg PD and Screen HRC (2012). "Specialization of tendon mechanical properties results from interfascicular differences." Journal of The Royal Society Interface vol. 9 (76), 3108-3117.
      07-11-2012
    • Anssari-Benam A, Legerlotz K, Bader DL and Screen HRC (2012). "On the specimen length dependency of tensile mechanical properties in soft tissues: gripping effects and the characteristic decay length." J Biomech vol. 45 (14), 2481-2482.
      21-09-2012
    • Screen HRC and Tanner KE (2012). "Structure and Biomechanics of Biological Composites." In Wiley Encyclopedia of Composites 
      20-07-2012
    • Legerlotz K, Jones ER, Screen HRC and Riley GP (2012). "Increased expression of IL-6 family members in tendon pathology." Rheumatology vol. 51 (7), 1161-1165.
      01-07-2012
    • Anssari-Benam A, Gupta HS and Screen HRC (2012). "Strain transfer through the aortic valve." Journal of Biomechanical Engineering vol. 134 (6)
      29-06-2012
    • Morrissey D, Graham J, Screen H, Sinha A, Small C, Twycross-Lewis R and Woledge R (2012). "Coronal plane hip muscle activation in football code athletes with chronic adductor groin strain injury during standing hip flexion." Manual Therapy vol. 17 (2), 145-149.
      01-04-2012
    • Screen HRC, Toorani S and Shelton JC (2012). "Microstructural stress relaxation mechanics in functionally different tendons." Medical Engineering and Physics
      01-01-2012

    2011

    • Screen HRC, Seto J, Krauss S, Boesecke P and Gupta HS (2011). "Extrafibrillar diffusion and intrafibrillar swelling at the nanoscale are associated with stress relaxation in the soft collagenous matrix tissue of tendons." Soft Matter vol. 7 (23), 11243-11251.
      07-11-2011
    • Anssari-Benam A, Bader DL and Screen HRC (2011). "Anisotropic time-dependant behaviour of the aortic valve." Journal of The Mechanical Behavior of Biomedical Materials vol. 4 (8), 1603-1610.
      01-11-2011
    • Simms C, Screen H and Evans S (2011). "Nonlinearities in soft tissue strain." J Mech Behav Biomed Mater vol. 4 (8)
      01-11-2011
    • Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH and Screen HRC (2011). "Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment." Proc Inst Mech Eng H vol. 225 (8), 821-830.
      01-08-2011
    • Morrissey D, Roskilly A, Twycross-Lewis R, Isinkaye T, Screen H, Woledge R and Bader D (2011). "The effect of eccentric and concentric calf muscle training on Achilles tendon stiffness." Clinical Rehabilitation vol. 25 (3), 238-247.
      01-03-2011
    • Anssari-Benam A, Bader DL and Screen HRC (2011). "A combined experimental and modelling approach to aortic valve viscoelasticity in tensile deformation." J Mater Sci-Mater M vol. 22 (2), 253-262.
      01-02-2011
    • Sweeney E, Chaudhury S, Screen H, Woledge R, Bader D, Maffulli N and Morrissey D (2011). "The effect of eccentric and concentric loading speed on the normal achilles tendon: an in vivo biomechanical study." British Journal of Sports Medicine vol. 45 (2)
      20-01-2011
    • Chaudhry S, Screen HRC, Woledge RC, Bader D and Morrissey D (2011). "The effect of loading speed on the force frequency spectrum during eccentric & concentric calf exercise." British Journal of Sports Medicine vol. 45 (2)
      20-01-2011
    • Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH and Screen HRC (2011). "Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment." P I Mech Eng H vol. 225 (H8), 821-830.
      01-01-2011

    2010

    • Legerlotz K, Riley GP and Screen HRC (2010). "Specimen dimensions influence the measurement of material properties in tendon fascicles." Journal of Biomechanics vol. 43 (12), 2274-2280.
      01-08-2010
    • Screen HRC, Byers S, Lynn AD, Nguyen V, Patel D and Bryant SJ (2010). "Characterization of a novel fiber composite material for mechanotransduction research of fibrous connective tissues." Advanced Functional Materials vol. 20 (5), 738-747.
      09-03-2010
    • Gupta HS, Seto J, Krauss S, Boesecke P and Screen HRC (2010). "In situ multi-level analysis of viscoelastic deformation mechanisms in tendon collagen." Journal of Structural Biology vol. 169 (2), 183-191.
      01-02-2010

    2009

    • Screen HRC and Evans SL (2009). "Measuring strain distributions in the tendon using confocal microscopy and finite elements." J Strain Anal Eng vol. 44 (5), 327-335.
      01-07-2009
    • SCREEN H (2009). "Hierarchical approaches to understanding tendon mechanics." Japan Society of Mechanical Engineers  Journal of Biomechanical Science and Engineering vol. 4 (4), 481-499.
      01-01-2009

    2008

    • Toorani S, Shelton JC and Screen HRC (2008). "Characterizing structure-function relationships in tendon." 8th World Biomaterials Congress 2008 vol. 2

      01-12-2008
    • Screen HRC (2008). "Investigating load relaxation mechanics in tendon." Journal of The Mechanical Behavior of Biomedical Materials vol. 1 (1), 51-58.
      01-01-2008

    2007

    2006

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