Prof Joost de Bruijn
BSc, PhD, FBSE
All Publications
Page 1 of 4
2020
- Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma
Holthof LC, Van Der Horst HJ, Van Hal-Van Veen SE, Ruiter RWJ, Li F, Buijze M, Andersen MN, Yuan H, De Bruijn J, Van De Donk NWCJ, Lokhorst HM, Zweegman S, Groen RWJ and Mutis T
Haematologica, Ferrata Storti Foundation vol. 105 (2), E80-E83.
31-01-2020 - Macrophage polarization plays roles in bone formation instructed by calcium phosphate ceramics.
Li M, Guo X, Qi W, Wu Z, de Bruijn JD, Xiao Y, Bao C and Yuan H
Journal of Materials Chemistry B, Royal Society of Chemistry
22-01-2020 - MagnetOs, Vitoss, and Novabone in a Multi-endpoint Study of Posterolateral Fusion: A True Fusion or Not?
van Dijk LA, Barrère-de Groot F, Rosenberg AJWP, Pelletier M, Christou C, de Bruijn JD and Walsh WR
Clinical Spine Surgery, Lippincott, Williams & Wilkins
21-01-2020
2019
- Bone Morphogenetic Protein 4 Gene Therapy in Mice Inhibits Myeloma Tumor Growth, But Has a Negative Impact on Bone.
Westhrin M, Holien T, Zahoor M, Moen SH, Buene G, Størdal B, Hella H, Yuan H, de Bruijn JD, Martens A, Groen RW, Bosch F, Smith U, Sponaas A-M, Sundan A and Standal T
Jbmr Plus, Wiley vol. 4 (1), e10247-e10247.
23-10-2019 - Preparing for cell culture scale-out: establishing parity of bioreactor- and flask-expanded mesenchymal stromal cell cultures.
Das R, Roosloot R, van Pel M, Schepers K, Driessen M, Fibbe WE, de Bruijn JD and Roelofs H
J Transl Med vol. 17 (1), 241-241.
24-07-2019 - Combined CD28 and 4-1BB Costimulation Potentiates Affinity-tuned Chimeric Antigen Receptor-engineered T Cells.
Drent E, Poels R, Ruiter R, van de Donk NWCJ, Zweegman S, Yuan H, de Bruijn J, Sadelain M, Lokhorst HM, Groen RWJ, Mutis T and Themeli M
Clin Cancer Res vol. 25 (13), 4014-4025.
12-04-2019 - CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia
Naik J, Themeli M, de Jong-Korlaar R, Ruiter RWJ, Poddighe PJ, Yuan H, de Bruijn JD, Ossenkoppele GJ, Zweegman S, Smit L, Mutis T, Martens ACM, van de Donk NWCJ and Groen RWJ
Haematologica vol. 104 (3), e100-e103.
28-02-2019 - Accelerated bone formation by biphasic calcium phosphate with a novel sub-micron surface topography.
Duan R, van Dijk LA, Barbieri D, de Groot F, Yuan H and de Bruijn JD
Eur Cell Mater vol. 37, 60-73.
28-01-2019 - Efficacy of a synthetic calcium phosphate with submicron surface topography as autograft extender in lapine posterolateral spinal fusion.
van Dijk LA, Barbieri D, Barrère-de Groot F, Yuan H, Oliver R, Christou C, Walsh WR and de Bruijn JD
J Biomed Mater Res B Appl Biomater
07-01-2019
2018
- Biphasic calcium phosphate with submicron surface topography in an Ovine model of instrumented posterolateral spinal fusion.
van Dijk LA, Duan R, Luo X, Barbieri D, Pelletier M, Christou C, Rosenberg AJWP, Yuan H, Barrèrre-de Groot F, Walsh WR and de Bruijn JD
Jor Spine vol. 1 (4), e1039-e1039.
28-11-2018 - Modulating Bone Regeneration in Rabbit Condyle Defects with Three Surface-Structured Tricalcium Phosphate Ceramics
Duan R, Barbieri D, De Groot F, De Bruijn JD and Yuan H
Acs Biomaterials Science and Engineering vol. 4 (9), 3347-3355.
10-09-2018
2017
- Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis.
Zhang J, Dalbay MT, Luo X, Vrij E, Barbieri D, Moroni L, de Bruijn JD, van Blitterswijk CA, Chapple JP, Knight MM and Yuan H
Acta Biomater vol. 57, 487-497.
15-07-2017 - Genetically engineered mesenchymal stromal cells produce IL-3 and TPO to further improve human scaffold-based xenograft models
Carretta M, de Boer B, Jaques J, Antonelli A, Horton SJ, Yuan H, de Bruijn JD, Groen RWJ, Vellenga E and Schuringa JJ
Experimental Hematology vol. 51, 36-46.
01-07-2017 - A Rational Strategy for Reducing On-Target Off-Tumor Effects of CD38-Chimeric Antigen Receptors by Affinity Optimization
Drent E, Themeli M, Poels R, de Jong-Korlaar R, Yuan H, de Bruijn J, Martens ACM, Zweegman S, van de Donk NWCJ, Groen RWJ, Lokhorst HM and Mutis T
Molecular Therapy vol. 25 (8), 1946-1958.
13-05-2017 - * Comparison of Two Moldable Calcium Phosphate-Based Bone Graft Materials in a Noninstrumented Canine Interspinous Implantation Model.
Barbieri D, Yuan H, Ismailo¿lu AS and de Bruijn JD
Tissue Eng Part A vol. 23 (23-24), 1310-1320.
28-02-2017 - Cells responding to surface structure of calcium phosphate ceramics for bone regeneration.
Zhang J, Sun L, Luo X, Barbieri D, de Bruijn JD, van Blitterswijk CA, Moroni L and Yuan H
J Tissue Eng Regen Med
08-02-2017
2016
- Establishing human leukemia xenograft mouse models by implanting human bone marrow-2 like scaffold-based niches
DE BRUIJN JD
Blood, American Society of Hematology
22-12-2016 - Sepantronium bromide (YM155) improves daratumumab-mediated cellular lysis of multiple myeloma cells by abrogation of bone marrow stromal cell-induced resistance.
de Haart SJ, Holthof L, Noort WA, Minnema MC, Emmelot ME, Aarts-Riemens T, Doshi P, Sasser K, Yuan H, de Bruijn J, Martens AC, van de Donk NW, Lokhorst HM, Groen RW and Mutis T
Haematologica vol. 101 (8), e339-e342.
01-08-2016 - COST-EFFICIENT, CLOSED-SYSTEM MSC CULTURE TO THERAPEUTICALLY RELEVANT QUANTITIES
Das R, Roosloot R, Burer J, Driessen M, Tra W, van Santen P and de Bruijn J
Cytotherapy vol. 18 (6), S81-S82.
01-06-2016 - ONE-STEP BONE MARROW-DERIVED MSC CULTURE USING NOVEL BIOREACTOR TECHNOLOGY
Das R, Roosloot R, Burer J, Zuijderduijn R, Roelofs H, van Santen P and de Bruijn J
Cytotherapy vol. 18 (6), S80-S81.
01-06-2016 - Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft model
Sontakke P, Carretta M, Jaques J, Brouwers-Vos AZ, Lubbers-Aalders L, Yuan H, de Bruijn JD, Martens ACM, Vellenga E, Groen RWJ and Schuringa JJ
Leukemia
17-05-2016 - Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma
Drent E, Groen RWJ, Noort WA, Themeli M, van Bueren JJL, Parren PWHI, Kuball J, Sebestyen Z, Yuan H, de Bruijn J, van de Donk NWCJ, Martens ACM, Lokhorst HM and Mutis T
Haematologica vol. 101 (5), 616-625.
30-04-2016
2015
- International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials
Galipeau J, Krampera M, Barrett J, Dazzi F, Deans RJ, DeBruijn J, Dominici M, Fibbe WE, Gee AP, Gimble JM, Hematti P, Koh MBC, LeBlanc K, Martin I, McNiece IK, Mendicino M, Oh S, Ortiz L, Phinney DG, Planat V, Shi Y, Stroncek DF, Viswanathan S, Weiss DJ and Sensebe L
Cytotherapy vol. 18 (2), 151-159.
17-11-2015 - CULTURE OF ADIPOSE-DERIVED STEM CELLS IN A CLOSED BIOREACTOR SYSTEM FOR CELL THERAPY
Tra W, Das R, Driessen M, van Santen P and de Bruijn J
Cytotherapy vol. 17 (6), S44-S44.
01-06-2015 - Effect of particle size on osteoinductive potential of microstructured biphasic calcium phosphate ceramic
Wang L, Barbieri D, Zhou H, De Bruijn JD, Bao C and Yuan H
Journal of Biomedical Materials Research - Part A vol. 103 (6), 1919-1929.
01-06-2015 - Influence of fluoride in poly(d, l -lactide)/apatite composites on bone formation
Luo X, Barbieri D, Passanisi G, Yuan H and De Bruijn JD
Journal of Biomedical Materials Research - Part B Applied Biomaterials vol. 103 (4), 841-852.
01-05-2015 - The RAPIDOS project-European and Chinese collaborative research on biomaterials.
Eglin D, Alini M, de Bruijn J, Gautrot J, Grijpma DW, Kamer L, Lai Y, Lu S, Peijs T, Peng J, Tang TT, Wang X, Richards RG and Qin L
J Orthop Translat vol. 3 (2), 78-84.
20-03-2015 - Microporous calcium phosphate ceramics driving osteogenesis through surface architecture
Zhang J, Barbieri D, Ten Hoopen H, De Bruijn JD, Van Blitterswijk CA and Yuan H
Journal of Biomedical Materials Research - Part A vol. 103 (3), 1188-1199.
01-03-2015 - Influence of surface microstructure and chemistry on osteoinduction and osteoclastogenesis by biphasic calcium phosphate discs
Davison NL, Su J, Yuan H, van den Beucken JJJP, de Bruijn JD and de Groot FB
European Cells and Materials vol. 29, 314-329.
01-01-2015
2014
- The size of surface microstructures as an osteogenic factor in calcium phosphate ceramics.
Zhang J, Luo X, Barbieri D, Barradas AMC, de Bruijn JD, van Blitterswijk CA and Yuan H
Acta Biomater vol. 10 (7), 3254-3263.
01-07-2014 - Submicron-scale surface architecture of tricalcium phosphate directs osteogenesis in vitro and in vivo
Davison NL, Luo X, Schoenmaker T, Everts V, Yuan H, Barrère-de Groot F and de Bruijn JD
European Cells and Materials vol. 27, 281-297.
15-04-2014 - CONTROLLED CULTURE OF ADHERENT CELLS IN A NOVEL, CLOSED BIOREACTOR SYSTEM FOR CELL THERAPY PRODUCTION
Das R, Roosloot R, Tra W, Roelofs H, van Santen P and de Bruijn J
Cytotherapy vol. 16 (4), S102-S103.
01-04-2014 - Poly(trimethylene carbonate) and biphasic calcium phosphate composites for orbital floor reconstruction: A feasibility study in sheep
van Leeuwen AC, Yuan H, Passanisi G, van der Meer JW, de Bruijn JD, van Kooten TG, Grijpma DW and Bos RRM
European Cells and Materials vol. 27, 81-97.
31-01-2014 - Effect of particle size on osteoinductive potential of microstructured biphasic calcium phosphate ceramic
Wang L, Barbieri D, Zhou H, de Bruijn JD, Bao C and Yuan H
Journal of Biomedical Materials Research - Part A, John Wiley and Sons Inc.
01-01-2014 - Liposomal clodronate inhibition of osteoclastogenesis and osteoinduction by submicrostructured beta-tricalcium phosphate
Davison NL, Gamblin AL, Layrolle P, Yuan H, de Bruijn JD and Barrère-de Groot F
Biomaterials vol. 35 (19), 5088-5097.
01-01-2014 - Microporous calcium phosphate ceramics driving osteogenesis through surface architecture
Zhang J, Barbieri D, ten Hoopen H, de Bruijn JD, van Blitterswijk CA and Yuan H
Journal of Biomedical Materials Research - Part A
01-01-2014 - Osteoclast resorption of beta-tricalcium phosphate controlled by surface architecture
Davison NL, ten Harkel B, Schoenmaker T, Luo X, Yuan H, Everts V, Barrère-de Groot F and de Bruijn JD
Biomaterials vol. 35 (26), 7441-7451.
01-01-2014 - Poly(trimethylene carbonate) and biphasic calcium phosphate composites for orbital floor reconstruction: A feasibility study in sheep
van Leeuwen AC, Yuan H, Passanisi G, van der Meer JW, de Bruijn JD, van Kooten TG, Grijpma DW and Bos RRM
European Cells and Materials vol. 27, 81-97.
01-01-2014 - The morphology and functions of articular chondrocytes on a honeycomb-patterned surface.
Eniwumide JO, Tanaka M, Nagai N, Morita Y, de Bruijn J, Yamamoto S, Onodera S, Kondo E, Yasuda K and Shimomura M
Biomed Res Int vol. 2014
01-01-2014 - Zinc in calcium phosphate mediates bone induction: In vitro and in vivo model
Luo X, Barbieri D, Davison N, Yan Y, De Bruijn JD and Yuan H
Acta Biomaterialia vol. 10 (1), 477-485.
01-01-2014
2013
- Influence of polymer molecular weight in osteoinductive composites for bone tissue regeneration
Barbieri D, Yuan H, Luo X, Farè S, Grijpma DW and De Bruijn JD
Acta Biomaterialia vol. 9 (12), 9401-9413.
01-12-2013 - Comparing autograft, allograft, and tricalcium phosphate ceramic in a goat instrumented posterolateral fusion model
Delawi D, Kruyt MC, Huipin Y, Vincken KL, De Bruijn JD, Oner FC and Dhert WJA
Tissue Engineering - Part C: Methods vol. 19 (11), 821-828.
01-11-2013 - Controlling dynamic mechanical properties and degradation of composites for bone regeneration by means of filler content
Barbieri D, de Bruijn JD, Luo X, Farè S, Grijpma DW and Yuan H
Journal of The Mechanical Behavior of Biomedical Materials vol. 20, 162-172.
01-04-2013 - Continuous and Uninterrupted Oxygen Tension Influences the Colony Formation and Oxidative Metabolism of Human Mesenchymal Stem Cells
Pattappa G, Thorpe SD, Jegard NC, Heywood HK, de Bruijn JD and Lee DA
Tissue Engineering Part C-Methods vol. 19 (1)
01-01-2013 - Influence of polymer molecular weight in osteoinductive composites for bone tissue regeneration
Barbieri D, Yuan H, Luo X, Farè S, Grijpma DW and de Bruijn JD
Acta Biomaterialia
01-01-2013 - Zinc in calcium phosphate mediates bone induction: In vitro and in vivo model
Luo X, Barbieri D, Davison N, Yan Y, de Bruijn JD and Yuan H
Acta Biomaterialia
01-01-2013
2012
- Reconstructing the human hematopoietic niche in immunodeficient mice: Opportunities for studying primary multiple myeloma
Groen RWJ, Noort WA, Raymakers RA, Prins HJ, Aalders L, Hofhuis FM, Moerer P, Van Velzen JF, Bloem AC, Van Kessel B, Rozemuller H, Van Binsbergen E, Buijs A, Yuan H, De Bruijn JD, De Weers M, Parren PWHI, Schuringa JJ, Lokhorst HM, Mutis T and Martens ACM
Blood vol. 120 (3)
19-07-2012 - In vivo performance of microstructured calcium phosphate formulated in novel water-free carriers
Davison N, Yuan H, de Bruijn JD and Barrere-de Groot F
Acta Biomaterialia vol. 8 (7), 2759-2769.
01-07-2012 - Patterns of Amino Acid Metabolism by Proliferating Human Mesenchymal Stem Cells
Higuera GA, Schop D, Spitters TWGM, van Dijkhuizen-Radersma R, Bracke M, de Bruijn JD, Martens D, Karperien M, van Boxtel A and van Blitterswijk CA
Tissue Engineering Part A vol. 18 (5-6), 654-664.
01-03-2012
2011
- Load-bearing composite for bone regeneration
Barbieri D, Altomare L, Xu Q, Farè S, Grijpma DW, De Bruijn JD and Yuan H
24th European Conference On Biomaterials - Annual Conference of The European Society For Biomaterials
01-12-2011