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Smart Matrices for Minimally Invasive Regenerative Medicine

Principal investigator: Alvaro MATA
Co-investigator(s): D. Eglin (AO Research Institute Davos Switzerland) and C. Semino (Institute Quimic de Sarria Barcelona Spain)

This project aims to develop a novel injectable bioactive matrix for cartilage and bone regeneration. The material is based on a functionalized hyaluronic acid with a thermosensitive segment and bioactive dendrimers capable of providing reversible liquid-to-gel assembly upon temperature change, a biocompatible 3D environment for cell growth, and a cocktail of bioactive signals designed to stimulate specific biological responses.