Smart Matrices for Minimally Invasive Regenerative Medicine
|Principal investigator:||Alvaro MATA|
|Co-investigator(s):||D. Eglin (AO Research Institute Davos Switzerland) and C. Semino (Institute Quimic de Sarria Barcelona Spain)|
This project aims to develop a novel injectable bioactive matrix for cartilage and bone regeneration. The material is based on a functionalized hyaluronic acid with a thermosensitive segment and bioactive dendrimers capable of providing reversible liquid-to-gel assembly upon temperature change, a biocompatible 3D environment for cell growth, and a cocktail of bioactive signals designed to stimulate specific biological responses.