Fatigue Damage in tendon tissue

Principal investigator: Hazel SCREEN
Co-investigator(s): G. Riley, T. Demirci and J. Shepherd
Funding source(s): Wellcome Trust
 Start: 01-04-2009  /  End: 31-03-2013
 Amount: £182,982
Directly incurred staff: Taylan Demirci, Jennifer Shepherd

Histological section of tendon, showing the organised arrangement of the collagenThis Wellcome funded project is interested in how fatigue accumulates in our tissues, and how overloading can lead to localised structural damage. We are interested in characterising this damage and the effect is has on cell mechanics in order to determine how fatigue may accumulate in different tendons, and its effect on the tissue functionality.