The regulation of mechanosensing in healthy and atherosclerotic VSMC
|Funding source(s): ||BHF British Heart Foundation|
| ||Start: 01-12-2020 / End: 30-11-2023|
| ||Amount: £238,021|
Vascular smooth muscle cellsplay a central role in the onset and progression of many cardiovascular diseases, from atherosclerosis to vascular injury, where their migration, matrix secretion, or degradation functions are deregulated. Here we are investigating how the phenotypic switch is regulated through physical/mechanical stimuli.