High-resolution mapping of chemical activity of cells on surfaces is important for the understanding biological processes. We are aiming to develop the first flexible and biocompatible electrochemical imaging chip for in-vivo imaging of cell activity. The groundwork for this will be laid by this PhD project by developing novel organic semiconductor coatings suitable for high-resolution photocurrent imaging and measurement of cell-signalling processes such as cell impedance, cell surface charges, release of metabolites and neurotransmitters.