Dr Stefaan Verbruggen
BEng, PhD, FHEA
Key Publications
- Verbruggen SW, Nolan J, Duffy MP, Pearce OMT, Jacobs CR and Knight MM (2023). A Novel Primary Cilium‐Mediated Mechanism Through which Osteocytes Regulate Metastatic Behavior of Both Breast and Prostate Cancer Cells. Wiley: Advanced Science vol. 11 (2)
15-11-2023 - Schurman CA, Verbruggen SW and Alliston T (2021). Disrupted osteocyte connectivity and pericellular fluid flow in bone with aging and defective TGF-β signaling. Proceedings of The National Academy of Sciences: Proceedings of The National Academy of Sciences of The United States of America vol. 118 (25)
14-06-2021 - Verbruggen SW, Thompson CL, Duffy MP, Lunetto S, Nolan J, Pearce OMT, Jacobs CR and Knight MM (2021). Mechanical Stimulation Modulates Osteocyte Regulation of Cancer Cell Phenotype. Mdpi: Cancers vol. 13 (12)
10-06-2021 - Verbruggen SW, Kainz B, Shelmerdine SC, Hajnal JV, Rutherford MA, Arthurs OJ, Phillips ATM and Nowlan NC (2018). Stresses and strains on the human fetal skeleton during development. The Royal Society: Journal of The Royal Society Interface vol. 15 (138)
01-01-2018 - Verbruggen SW, Oyen ML, Phillips ATM and Nowlan NC (2017). Function and failure of the fetal membrane: Modelling the mechanics of the chorion and amnion. Plos One vol. 12 (3), e0171588-e0171588.
28-03-2017
All Publications
2024
- Verbruggen SW, Freeman CL and Freeman FE (2024). Utilizing 3D Models to Unravel the Dynamics of Myeloma Plasma Cells’ Escape from the Bone Marrow Microenvironment. Cancers, Mdpi vol. 16 (5)
22-02-2024 - Verbruggen SW (2024). Role of the osteocyte in bone metastasis – The importance of networking. Journal of Bone Oncology, Elsevier vol. 44
17-01-2024
2023
- Verbruggen SW, Nolan J, Duffy MP, Pearce OMT, Jacobs CR and Knight MM (2023). A Novel Primary Cilium‐Mediated Mechanism Through which Osteocytes Regulate Metastatic Behavior of Both Breast and Prostate Cancer Cells. Advanced Science, Wiley vol. 11 (2)
15-11-2023 - Verbruggen SW, Sittichokechaiwut A and Reilly GC (2023). Osteocytes and Primary Cilia. Current Osteoporosis Reports, Springer
08-09-2023 - Asbai-Ghoudan R, Nasello G, Pérez MÁ, Verbruggen SW, Ruiz de Galarreta S and Rodriguez-Florez N (2023). In silico assessment of the bone regeneration potential of complex porous scaffolds. Computers in Biology and Medicine, Elsevier vol. 165
14-08-2023 - Sutton MM, Duffy MP, Verbruggen SW and Jacobs CR (2023). Osteoclastogenesis requires primary cilia disassembly and can be inhibited by promoting primary cilia formation pharmacologically. Cells Tissues Organs, Karger Publishers, 1-10.
22-05-2023 - Nolan J, Pearce OMT, Screen HRC, Knight MM and Verbruggen SW (2023). Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK. Cancers, Mdpi vol. 15 (3)
19-01-2023
2021
- Schurman CA, Verbruggen SW and Alliston T (2021). Disrupted osteocyte connectivity and pericellular fluid flow in bone with aging and defective TGF-β signaling. Proceedings of The National Academy of Sciences of The United States of America, Proceedings of The National Academy of Sciences vol. 118 (25)
14-06-2021 - Verbruggen SW, Thompson CL, Duffy MP, Lunetto S, Nolan J, Pearce OMT, Jacobs CR and Knight MM (2021). Mechanical Stimulation Modulates Osteocyte Regulation of Cancer Cell Phenotype. Cancers, Mdpi vol. 13 (12)
10-06-2021
2018
- Verbruggen SW, Kainz B, Shelmerdine SC, Arthurs OJ, Hajnal JV, Rutherford MA, Phillips ATM and Nowlan NC (2018). European Society of Biomechanics S.M. Perren Award 2018: Altered biomechanical stimulation of the developing hip joint in presence of hip dysplasia risk factors. Journal of Biomechanics, Elsevier vol. 78, 1-9.
20-07-2018 - Verbruggen SW, Kainz B, Shelmerdine SC, Hajnal JV, Rutherford MA, Arthurs OJ, Phillips ATM and Nowlan NC (2018). Stresses and strains on the human fetal skeleton during development. Journal of The Royal Society Interface, The Royal Society vol. 15 (138)
01-01-2018
2017
- Verbruggen SW, Oyen ML, Phillips ATM and Nowlan NC (2017). Function and failure of the fetal membrane: Modelling the mechanics of the chorion and amnion. Plos One vol. 12 (3), e0171588-e0171588.
28-03-2017 - Verbruggen SW and Nowlan NC (2017). Ontogeny of the Human Pelvis. The Anatomical Record, Wiley vol. 300 (4), 643-652.
15-03-2017
2016
- Giorgi M, Verbruggen SW and Lacroix D (2016). In silico bone mechanobiology: modeling a multifaceted biological system. Wires Mechanisms of Disease, Wiley vol. 8 (6), 485-505.
07-09-2016 - Verbruggen SW, Vaughan TJ and McNamara LM (2016). Mechanisms of osteocyte stimulation in osteoporosis. Journal of The Mechanical Behavior of Biomedical Materials, Elsevier vol. 62, 158-168.
10-05-2016
2015
- Verbruggen SW, Loo JHW, Hayat TTA, Hajnal JV, Rutherford MA, Phillips ATM and Nowlan NC (2015). Modeling the biomechanics of fetal movements. Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 15 (4), 995-1004.
03-11-2015 - Verbruggen SW, Garrigle MJM, Haugh MG, Voisin MC and McNamara LM (2015). Altered Mechanical Environment of Bone Cells in an Animal Model of Short- and Long-Term Osteoporosis. Biophysical Journal, Elsevier vol. 108 (7), 1587-1598.
01-04-2015
2014
- Vaughan TJ, Mullen CA, Verbruggen SW and McNamara LM (2014). Bone cell mechanosensation of fluid flow stimulation: a fluid–structure interaction model characterising the role integrin attachments and primary cilia. Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 14 (4), 703-718.
16-11-2014
2013
- Vaughan TJ, Verbruggen SW and McNamara LM (2013). Are all osteocytes equal? Multiscale modelling of cortical bone to characterise the mechanical stimulation of osteocytes. International Journal For Numerical Methods in Biomedical Engineering, Wiley vol. 29 (12), 1361-1372.
29-07-2013 - Verbruggen SW, Vaughan TJ and McNamara LM (2013). Fluid flow in the osteocyte mechanical environment: a fluid–structure interaction approach. Biomechanics and Modeling in Mechanobiology, Springer Nature vol. 13 (1), 85-97.
09-04-2013
2012
- Verbruggen SW, Vaughan TJ and McNamara LM (2012). Strain amplification in bone mechanobiology: a computational investigation of the in vivo mechanics of osteocytes. Journal of The Royal Society Interface, The Royal Society vol. 9 (75), 2735-2744.
06-06-2012