Dr Stefaan Verbruggen
BEng, PhD, FHEA

 

All Publications

2025

  • Altered vertebral biomechanical properties in prostate cancer patients following androgen deprivation therapy
    Gibson FG, Paggiosi MA, Handforth C, Brown JE, Li X, Dall'Ara E, Verbruggen SW
    Bone, Elsevier Bv vol. 195, 117465-117465.  
    01-06-2025
  • You are what you breathe? Metabolites may begin to explain the link between air pollution and bone damage
    Verbruggen SW
    Journal of Bone and Mineral Research, Oxford University Press (Oup) vol. 40 (7), 825-826.  
    19-05-2025

2024

  • Air Pollution and Osteoporosis
    Allen O, Knight MM, Verbruggen SW
    Current Osteoporosis Reports, Springer Science and Business Media Llc vol. 22 (6), 590-598.  
    20-09-2024
  • Analytical and computational studies predict negligible risk of cell death from eddy generation off flat surfaces in cell culture flow systems
    Morley EJ, Brockett CL, Verbruggen SW
    Frontiers in Bioengineering and Biotechnology, Frontiers Media Sa vol. 12 
    07-08-2024
  • Utilizing 3D Models to Unravel the Dynamics of Myeloma Plasma Cells’ Escape from the Bone Marrow Microenvironment
    Verbruggen SW, Freeman CL, Freeman FE
    Cancers, Mdpi Ag vol. 16 (5), 889-889.  
    22-02-2024
  • Role of the osteocyte in bone metastasis – The importance of networking
    Verbruggen SW
    Journal of Bone Oncology, Elsevier Bv vol. 44, 100526-100526.  
    01-02-2024

2023

  • A Novel Primary Cilium‐Mediated Mechanism Through which Osteocytes Regulate Metastatic Behavior of Both Breast and Prostate Cancer Cells
    Verbruggen SW, Nolan J, Duffy MP, Pearce OMT, Jacobs CR, Knight MM
    Advanced Science, Wiley vol. 11 (2) 
    15-11-2023
  • In silico assessment of the bone regeneration potential of complex porous scaffolds
    Asbai-Ghoudan R, Nasello G, Pérez MÁ, Verbruggen SW, Ruiz de Galarreta S, Rodriguez-Florez N
    Computers in Biology and Medicine, Elsevier Bv vol. 165, 107381-107381.  
    01-10-2023
  • Osteocytes and Primary Cilia
    Verbruggen SW, Sittichokechaiwut A, Reilly GC
    Current Osteoporosis Reports, Springer Science and Business Media Llc vol. 21 (6), 719-730.  
    08-09-2023
  • Osteoclastogenesis Requires Primary Cilia Disassembly and Can Be Inhibited by Promoting Primary Cilia Formation Pharmacologically
    Sutton MM, Duffy MP, Verbruggen SW, Jacobs CR
    Cells Tissues Organs, S. Karger Ag vol. 213 (3), 235-244.  
    22-05-2023
  • Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK
    Nolan J, Pearce OMT, Screen HRC, Knight MM, Verbruggen SW
    Cancers, Mdpi Ag vol. 15 (3), 635-635.  
    19-01-2023

2021

  • Disrupted osteocyte connectivity and pericellular fluid flow in bone with aging and defective TGF-β signaling
    Schurman CA, Verbruggen SW, Alliston T
    Proceedings of The National Academy of Sciences, Proceedings of The National Academy of Sciences vol. 118 (25) 
    14-06-2021
  • Mechanical Stimulation Modulates Osteocyte Regulation of Cancer Cell Phenotype
    Verbruggen SW, Thompson CL, Duffy MP, Lunetto S, Nolan J, Pearce OMT, Jacobs CR, Knight MM
    Cancers, Mdpi Ag vol. 13 (12), 2906-2906.  
    10-06-2021

2018

  • European Society of Biomechanics S.M. Perren Award 2018: Altered biomechanical stimulation of the developing hip joint in presence of hip dysplasia risk factors
    Verbruggen SW, Kainz B, Shelmerdine SC, Arthurs OJ, Hajnal JV, Rutherford MA, Phillips ATM, Nowlan NC
    Journal of Biomechanics, Elsevier Bv vol. 78, 1-9.  
    01-09-2018
  • Stresses and strains on the human fetal skeleton during development
    Verbruggen SW, Kainz B, Shelmerdine SC, Hajnal JV, Rutherford MA, Arthurs OJ, Phillips ATM, Nowlan NC
    Journal of The Royal Society Interface, The Royal Society vol. 15 (138), 20170593-20170593.  
    01-01-2018

2017

  • Function and failure of the fetal membrane: Modelling the mechanics of the chorion and amnion
    Verbruggen SW, Oyen ML, Phillips ATM, Nowlan NC
    Plos One, Public Library of Science (Plos) vol. 12 (3), e0171588-e0171588.  
    28-03-2017
  • Ontogeny of the Human Pelvis
    Verbruggen SW, Nowlan NC
    The Anatomical Record, Wiley vol. 300 (4), 643-652.  
    15-03-2017

2016

  • In silico bone mechanobiology: modeling a multifaceted biological system
    Giorgi M, Verbruggen SW, Lacroix D
    Wires Systems Biology and Medicine, Wiley vol. 8 (6), 485-505.  
    07-09-2016
  • Mechanisms of osteocyte stimulation in osteoporosis
    Verbruggen SW, Vaughan TJ, McNamara LM
    Journal of The Mechanical Behavior of Biomedical Materials, Elsevier Bv vol. 62, 158-168.  
    01-09-2016

2015

  • Modeling the biomechanics of fetal movements
    Verbruggen SW, Loo JHW, Hayat TTA, Hajnal JV, Rutherford MA, Phillips ATM, Nowlan NC
    Biomechanics and Modeling in Mechanobiology, Springer Science and Business Media Llc vol. 15 (4), 995-1004.  
    03-11-2015
  • Altered Mechanical Environment of Bone Cells in an Animal Model of Short- and Long-Term Osteoporosis
    Verbruggen SW, Mc Garrigle MJ, Haugh MG, Voisin MC, McNamara LM
    Biophysical Journal, Elsevier Bv vol. 108 (7), 1587-1598.  
    01-04-2015

2014

  • Bone cell mechanosensation of fluid flow stimulation: a fluid–structure interaction model characterising the role integrin attachments and primary cilia
    Vaughan TJ, Mullen CA, Verbruggen SW, McNamara LM
    Biomechanics and Modeling in Mechanobiology, Springer Science and Business Media Llc vol. 14 (4), 703-718.  
    16-11-2014

2013

  • Are all osteocytes equal? Multiscale modelling of cortical bone to characterise the mechanical stimulation of osteocytes
    Vaughan TJ, Verbruggen SW, McNamara LM
    International Journal For Numerical Methods in Biomedical Engineering, Wiley vol. 29 (12), 1361-1372.  
    29-07-2013
  • Fluid flow in the osteocyte mechanical environment: a fluid–structure interaction approach
    Verbruggen SW, Vaughan TJ, McNamara LM
    Biomechanics and Modeling in Mechanobiology, Springer Science and Business Media Llc vol. 13 (1), 85-97.  
    09-04-2013

2012

  • Strain amplification in bone mechanobiology: a computational investigation of the\n in vivo\n mechanics of osteocytes
    Verbruggen SW, Vaughan TJ, McNamara LM
    Journal of The Royal Society Interface, The Royal Society vol. 9 (75), 2735-2744.  
    06-06-2012