Prof Rob Krams
MD, PhD
All Publications
Page 1 of 5
2025
- Non-lethal effects of predation risk enhance long-term memory in Drosophila melanogaster
Behaviour, De Gruyter vol. 162 (3-4), 227-241.
22-04-2025 - Great Tit (Parus major) Nestlings Have Longer Telomeres in Old‐Growth Forests Than in Young Forests
Ecology and Evolution, Wiley vol. 15 (1)
01-01-2025
2024
- Editorial: Computational modelling of cardiovascular hemodynamics and machine learning
Frontiers in Cardiovascular Medicine, Frontiers vol. 11
22-02-2024 - Assessment of the nano-mechanical properties of healthy and atherosclerotic coronary arteries by atomic force microscopy
Journal of The Royal Society Interface, The Royal Society vol. 21 (211)
01-02-2024
2023
- TCT-613 Comparison of Histology-Trained Deep Learning Approach With Human Expert Analysts for Automated Plaque Component Classification in Hybrid Intravascular Ultrasound-Optical Coherence Tomography Images
Journal of The American College of Cardiology, Elsevier vol. 82 (17), b246-b247.
01-10-2023 - Considering the Influence of Coronary Motion on Artery-Specific Biomechanics Using Fluid–Structure Interaction Simulation
Annals of Biomedical Engineering, Springer vol. 51 (9), 1950-1964.
12-07-2023 - Editorial: Computational modeling for assessing coronary artery pathophysiology
Frontiers in Cardiovascular Medicine, Frontiers Media vol. 10
17-01-2023
2022
- JAG1-NOTCH4 mechanosensing drives atherosclerosis
Science Advances, American Association For The Advancement of Science vol. 8 (35)
02-09-2022 - TCT-254 Histology-Trained Deep Learning Methodology for Automated Coronary Plaque Component Classification in Combined Intravascular Ultrasound-Optical Coherence Tomography Images
Journal of The American College of Cardiology, Elsevier vol. 80 (12)
01-09-2022
2021
- Mechanosensitive pathways are regulated by mechanosensitive miRNA clusters in endothelial cells
Biophysical Reviews, Springer (Part of Springer Nature) vol. 13 (5), 787-796.
23-10-2021 - Moving shear stress towards the clinic: preclinical comparison of optical coherence tomography-based versus angiography-based time-averaged wall shear stress estimations
European Heart Journal vol. 42 (Supplement_1)
12-10-2021 - Correction: BS18 Profiling endothelial gene expression in coronary atherosclerotic plaques in a human-like D374Y-PCSK9 hyperlipidaemic porcine model
Heart, Bmj vol. 107 (19), e10-e10.
14-09-2021 - Considerations for analysis of endothelial shear stress and strain in FSI models of atherosclerosis
Journal of Biomechanics, Elsevier vol. 128
28-08-2021
2020
- 3D co-registration algorithm for catheter-based optical coherence tomography
Optics Continuum, Optica Publishing Group vol. 3 (10)
17-09-2020 - Shear Stress Estimated by Quantitative Coronary Angiography Predicts Plaques Prone to Progress and Cause Events
Jacc Cardiovascular Imaging, Elsevier vol. 13 (10), 2206-2219.
13-05-2020 - Targeted Molecular Iron Oxide Contrast Agents for Imaging Atherosclerotic Plaque
Nanotheranostics, Ivyspring International Publisher vol. 4 (4), 184-194.
01-01-2020
2019
- Expert recommendations on the assessment of wall shear stress in human coronary arteries: existing methodologies, technical considerations, and clinical applications.
European Heart Journal, Oxford University Press (Oup)
30-09-2019 - Reliable in Vivo Intravascular Imaging Plaque Characterisation: A Challenge Unmet
American Heart Journal, Elsevier
23-07-2019 - The emerging role of YAP/TAZ in mechanotransduction.
J Thorac Dis vol. 9 (5), E507-E509.
01-05-2019 - Disturbed flow induces a sustained, stochastic NF-κB activation which may support intracranial aneurysm growth in vivo.
Sci Rep vol. 9 (1), 4738-4738.
18-03-2019 - Plaque burden influences accurate classification of fibrous cap atheroma by in vivo optical coherence tomography in a porcine model of advanced coronary atherosclerosis.
Eurointervention vol. 14 (10), 1129-1135.
20-02-2019
2018
- New developments in mechanotransduction: Cross talk of the Wnt, TGF-β and Notch signalling pathways in reaction to shear stress
Current Opinion in Biomedical Engineering vol. 5, 96-104.
01-03-2018
2017
- Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.
Circulation, American Heart Association, Inc vol. 136 (12), 1140-1154.
11-07-2017 - Connexin40 controls endothelial activation by dampening NFκB activation.
Oncotarget, Impact Journals vol. 8 (31), 50972-50986.
22-03-2017
2016
- Zebrafish Model for Functional Screening of Flow-Responsive Genes.
Arterioscler Thromb Vasc Biol, Wolters Kluwer Health, Inc vol. 37 (1), 130-143.
10-11-2016 - Disturbed Cyclical Stretch of Endothelial Cells Promotes Nuclear Expression of the Pro-Atherogenic Transcription Factor NF-κB.
Ann Biomed Eng, Springer Nature vol. 45 (4), 898-909.
27-10-2016 - Influence of shear stress magnitude and direction on atherosclerotic plaque composition
Royal Society Open Science, The Royal Society vol. 3 (10)
01-10-2016 - Development of a synthetic gene network to modulate gene expression by mechanical forces.
Sci Rep, Springer Nature vol. 6, 29643-29643.
12-07-2016 - 0109 : Connexin40 controls endothelial activation by dampening NF B activation
Archives of Cardiovascular Diseases Supplements vol. 8 (3), 203-203.
01-04-2016 - Comparison between direct and reverse electroporation of cells in situ: a simulation study
Physiological Reports, Wiley vol. 4 (6)
01-03-2016 - Corrigendum to “Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques” [J Mol Cell Cardiol] 89B (2015) 168–172
Journal of Molecular and Cellular Cardiology, Elsevier vol. 91
01-02-2016 - Integration of flow studies for robust selection of mechanoresponsive genes
Thrombosis and Haemostasis, Thieme vol. 115 (03), 474-483.
01-01-2016
2015
- Quantification of plaque stiffness by Brillouin microscopy in experimental thin cap fibroatheroma
Journal of The Royal Society Interface, The Royal Society vol. 12 (112)
01-11-2015 - Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques
Journal of Molecular and Cellular Cardiology, Elsevier vol. 89 (Pt B), 168-172.
30-10-2015 - Shear stress-induced atherosclerotic plaque composition in ApoE−/− mice is modulated by connexin37
Atherosclerosis, Elsevier vol. 243 (1), 1-10.
25-08-2015 - Inducing Persistent Flow Disturbances Accelerates Atherogenesis and Promotes Thin Cap Fibroatheroma Development in D374Y-PCSK9 Hypercholesterolemic Minipigs
Circulation, Wolters Kluwer vol. 132 (11), 1003-1012.
15-07-2015 - Enhancement of Non-Invasive Trans-Membrane Drug Delivery Using Ultrasound and Microbubbles During Physiologically Relevant Flow
Ultrasound in Medicine & Biology, Elsevier vol. 41 (9), 2435-2448.
09-06-2015 - Mammalian synthetic biology: emerging medical applications
Journal of The Royal Society Interface, The Royal Society vol. 12 (106)
01-05-2015 - Imaging phase separation in model lipid membranes through the use of BODIPY based molecular rotors
Physical Chemistry Chemical Physics, Royal Society of Chemistry (Rsc) vol. 17 (28), 18393-18402.
01-01-2015
2014
- Elevated Uptake of Plasma Macromolecules by Regions of Arterial Wall Predisposed to Plaque Instability in a Mouse Model
Plos One, Public Library of Science (Plos) vol. 9 (12)
22-12-2014 - A novel high-throughput platform for siRNA transfection of primary mammalian cells
Atherosclerosis, Elsevier vol. 237 (2)
01-12-2014 - A novel integrated platform for gene network inference and validation: beyond the dream consortium
Atherosclerosis, Elsevier vol. 237 (2)
01-12-2014 - Forecasting vulnerable plaque response to aemorheological flow
Atherosclerosis, Elsevier vol. 237 (2)
01-12-2014 - Longitudinal predictive analysis of vulnerable plaques in a mouse model of atherosclerosis
Atherosclerosis, Elsevier vol. 237 (2)
01-12-2014 - Symbolic representation and inference of regulatory networks: uncovering mechanosensitive gene networks
Atherosclerosis, Elsevier vol. 237 (2)
01-12-2014 - Biomechanical factors in atherosclerosis: mechanisms and clinical implications†
European Heart Journal, Oxford University Press (Oup) vol. 35 (43), 3013-3020.
17-09-2014 - In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18F-FEDAA1106
Molecular Imaging, Sage Publications vol. 13 (6)
01-08-2014 - In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18F-FEDAA1106.
Mol Imaging vol. 13 (6)
01-08-2014 - Thin-Cap Fibroatheroma Rupture Is Associated With a Fine Interplay of Shear and Wall Stress
Arteriosclerosis Thrombosis and Vascular Biology, Wolters Kluwer vol. 34 (10), 2224-2231.
24-07-2014 - Intimal hyperplasia following implantation of helical-centreline and straight-centreline stents in common carotid arteries in healthy pigs: influence of intraluminal flow
Journal of The Royal Society Interface, The Royal Society vol. 11 (92)
06-03-2014