Dr Timothy Hopkins
PhD

 

All Publications

2025

  • Increased synovitis and pro-inflammatory macrophage abundance are observed in the synovia of patients at risk of developing post-traumatic OA compared to those with established OA
    Hopkins T, Garcia J, Hulme CH, Tins B, Perry J, Jermin P, Gallacher P, Barnett A et al.
    Osteoarthritis and Cartilage Open, Elsevier Bv vol. 7 (3), 100643-100643.  
    01-09-2025
  • Engineering growth factor gradients to drive spatiotemporal tissue patterning in organ-on-a-chip systems
    Hopkins T, Midha S, Grossemy S, Screen HRC, Wann AKT, Knight MM
    Journal of Tissue Engineering, Sage Publications vol. 16 
    18-04-2025

2024

  • Intra-Articular Injection of Human Umbilical Cord-Derived Mesenchymal Stromal Cells Reduces Radiographic Osteoarthritis in an Ovine Model
    Perry J, Mennan C, Cool P, McCarthy HS, Newell K, Hopkins T, Hulme C, Wright KT et al.
    Cartilage, Sage Publications 
    03-11-2024

2023

  • Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment
    Thompson CL, Hopkins T, Bevan C, Screen HRC, Wright KT, Knight MM
    Biomedical Materials, IOP Publishing vol. 18 (6) 
    10-10-2023
  • Relationship Between Activity Level and Knee Function Is Influenced by Negative Affect in Patients Undergoing Cell Therapy for Articular Cartilage Defects in the Knee
    Hopkins T, Roberts S, Richardson JB, Gallacher P, Bailey A, Kuiper JH
    Orthopaedic Journal of Sports Medicine, Sage Publications vol. 11 (2) 
    01-02-2023

2022

  • Chondrocyte Isolation and Expansion
    Harrison P, Hopkins T, Hulme C, McCarthy H, Wright K
    In Methods in Molecular Biology, Springer Us 9-19.  
    11-11-2022

2021

  • Identifying Consensus and Open Questions around Assessing or Predicting the Quality and Success of Cartilage Repair: A Delphi Study
    Hopkins T, Richardson J, Kuiper JH
    Surgeries, Mdpi Ag vol. 2 (3), 286-302.  
    06-08-2021
  • An In Vitro System to Study the Effect of Subchondral Bone Health on Articular Cartilage Repair in Humans
    Hopkins T, Wright KT, Kuiper NJ, Roberts S, Jermin P, Gallacher P, Kuiper JH
    Cells, Mdpi Ag vol. 10 (8), 1903-1903.  
    27-07-2021
  • Short-Term Evaluation of Cellular Fate in an Ovine Bone Formation Model
    Markides H, Foster NC, McLaren JS, Hopkins T, Black C, Oreffo ROC, Scammell BE, Echevarria I et al.
    Cells, Mdpi Ag vol. 10 (7), 1776-1776.  
    14-07-2021

2020

  • The use of technology in the subcategorisation of osteoarthritis: a Delphi study approach
    Mennan C, Hopkins T, Channon A, Elliott M, Johnstone B, Kadir T, Loughlin J, Peffers M et al.
    Osteoarthritis and Cartilage Open, Elsevier Bv vol. 2 (3), 100081-100081.  
    01-09-2020

2019

  • Combined Autologous Chondrocyte and Bone Marrow Mesenchymal Stromal Cell Implantation in the Knee: An 8-year Follow Up of Two First-In-Man Cases
    Wang J, Wright KT, Perry J, Tins B, Hopkins T, Hulme C, McCarthy HS, Brown A et al.
    Cell Transplantation, Sage Publications vol. 28 (7), 924-931.  
    08-05-2019