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Prof Martin Knight
BEng, MSc, PhD, FHEA


Research Group Members

Prof Knight has a large multidisciplinary research group with expertise including biomedical engineering, biomechanics, cell physiology, molecular biology, organ-on-a-chip technology, cancer and musculoskeletal disease. The group currently consists of 4 post docs and 8 current PhD students with additional project students studying biomedical engineering at undergraduate and MSc level. We are actively seeking collaboration with externally funded research fellows and PhD students.

Postdoctoral Research Assistants

Dr Thompson
Prof Knight
Dr Inamdar
INAMDAR, Sheetal
Prof Knight
NOLAN, Joanne

Current PhD Students

NameThesis Title
BADAR, WaqasNanoscale damage markers for early osteoarthritis detection in the bone-cartilage unit
BEJA FERREIRA, MartaBiophysical biomarkers to characterize cancer-associated fibroblasts in drug screening strategies.
GARCIA SANCHEZ, BrendaNovel Models of Tendinopathy on a Chip
JURADO TERRAZAS, DarielOrgan-on-a-chip model of cartilage disease
MCFIE, MeganDevelopment of high throughput imaging screen of compounds effecting primary cilia structure and resulting modulation of mechanosignalling and other cilia functions in chondrocytes.
MENG, HuanThe effect of substrate stiffness on primary cilia and regulation of the tumour microenvironment.
SAMAD, HudairMicrofluidics for sorting circulating tumor cells
ZHANG, JinshuaiSynthesis of hybrid perovskite single crystals and study of their optoelectronic and photonic properties with nano/microstructures

PhD Graduates

NameThesis Title
ZHANG, XiaoliThe role of phosphorylation Ezrin in regulating the relationship between biophysical properties and cell migration (2020)
FU, SuThe role of primary cilia in the anti-inflammatory effects of mechanical loading in cartilage cells. (2019)
LUO, PiaopiaoMircrofluidic-based Model of the Microvasculature to Study the Impact of Glycocalyx on Angiogenesis (2019)
INAMDAR, SheetalNanoscale mechanics of collagen in articular cartilage (2018)
ROWSON, DanielThe role of primary cilia in tendinopathy (2018)
XU, JingThe effects of cobalt and chromium ions and nanoparticles on macrophage and fibroblast behaviour (2018)
DALBAY, MelisRoles of primary cilia in hMSC in differentiation (2016)
WANG, ZhaoThe effects of the rate of hypo-osmotic challenge and IFT88 mutation on the biomechanics of chondrocytes. (2016)
SLIOGERYTE, KristinaMechanical properties of stem cells using micropipette aspiration (2015)
DE VILLIERS, Danielle SimoneAccelerated wear protocols for understanding clinical wear in modern hip prostheses (2014)
IRIANTO, JeromeNuclear Related Responses to Osmotic Challenge in Chondrocytes (2013)
THOMPSON, ClaireInteraction between primary cilia length and hedgehog signalling in response to mechanical and thermal stress (2013)
PRAVINCUMAR, PriyankaViscoelastic Response of Cells and the Role of Actin Cytoskeletal Remodelling (2012)
HOSNY, NeveenDevelopment of a non-invasive method to detect pericellular spatial oxygen gradients using FLIM (2011)
VAUGHAN, NatalieThe potential of pulsed low-intensity ultrasound to stimulate chondrocytes in a 3D model system (2009)
BARIA, KatherineModulation of the effect of tensile strain on fibroblasts by extracellular matrix molecules and serum (2006)
PINGGUAN, BCalcium mediated signalling pathways for chondrocytes in 3D constructs subjected to cyclic loading (2006)