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Dr Oliver Pearce


Research Funding

Current Funded Research Projects

Organ-on-a-chip model of breast cancer bone metastases

Funding source: CR-UK Cancer Research UK
Start: 01-12-2020  /  End: 31-05-2023
Amount: £268,711

Background A common site for invasive ductal carcinomas (IDC) metastasis is bone, affecting about 70% of patients. Once metastasis to bone has occurred the five-year survival rate drops from 99% to 29%.  How breast cancer metastasises to bone is poorly understood, partly because of the lack of appropriate models. Organ-on-a-chip technology is …