Dr Joanne Nolan
Centre Scientist, QM+Emulate Organs-on-Chips Centre
Engineering 323, Mile End
|Supervisors:||Prof Martin Knight, Dr Oliver Pearce|
|Expertise:||I joined Queen Mary in 2021 working on an interdisciplinary CRUK-EPSRC funded project across both SEMS and Barts Cancer Institute. This work, in partnership with Emulate, focused on developing a new organ-on-a-chip model of breast cancer bone metastasis to study the interactions between breast cancer and bone cells. I currently manage the QM+Emulates Centre's suite of Human Emulation Systems with specialist training in the use of the platform. This involves leading the development of new models within the centre and providing support and training for research teams in the design, preparation and analysis of studies and development of research proposals.|
|Affiliations:||Irish Association for Cancer Research, European Association for Cancer Research (Ambassador), American Association for Cancer Research, Biochemical Society.|
I received my PhD from the University of Limerick, Ireland, where my research focused on breast cancer and how the extracellular matrix (ECM) influences cancer cell phenotype. This research investigated how individual components of the ECM regulate breast cancer cell behaviour across a range of breast cancer subtypes but also focused on how tissue stiffness combined with ECM composition has a distinct effect on cancer cells.