A note on cookies

We use cookies to improve your experience of our website. Privacy Policy

Queen Mary University of LondonQueen Mary University of London
Events menu

Programme and Abstracts

Abstracts Booklet »

Jump to:

Thursday 11th April 2019

08:00-08:50 Coffee, Registration, Poster set-up 
08:50-09:00 Opening: Anthony Bull
09:00-09:30 Keynote Lecture 1 Chair:  Rob Krams
  Yiannis Ventikos , UCL, London, UK
The role of blood flow and inflammation on cerebral aneurysm formation.
09:30-10:45 Cellular mechanosensors Chairs: Hanjoong Jo and J. Serbanovic-Canic
09:30-09:50 Ellie Tzima , Oxford University, UK
The role of PECAM1 in mechano-sensing
09:50-10:10 David Beech, University of Leeds, UK
Piezo-1 and calcium in mechano-sensing
10:10-10:30 Julien Vermot, IGBMC, France
Cilia and their role in mechano-sensing
10:30-10:45 John Tarbell, New York, USA
The role of the mechanosensing endothelial glycocalyx in matrix stiffness-mediated vascular disease
10:45-11:15 Coffee break
11:15-13:00 Mechano Predictors of Atherosclerosis. Chairs: John Oshinski and Peter Weinberg 
11:15-11:35 Ranil de Silva, Imperial College London, UK
Evaluation of shear stress and strain in pig coronaries
11:35-11:55 Peter Stone, Harvard University, US
Spatial relationships among local endothelial shear stress, minimal luminal area, and near-infrared spectroscopy lipid signal in patients with coronary artery disease:Implications for plaque destabilization
11:55-12:15 Martin Schwartz, Yale, Manchester, UK/USA
The role of NFkB in mechanotransduction
12:15-12:30 Stephane Avril, Fr
On the role played by wall shear stress in the alteration of biomechanical properties of ascending thoracic aortic aneurysms
12:30-12:45 Eline Hartman, ErasmusMC, The Netherlands
The synergistic effect of NIRS-detected lipid-rich plaque and five different wall shear stress metrics on human coronary plaque growth
12:45-13:00 Blanca Tardajos Ayllón, Sheffield, UK
c-Rel drives atherosclerosis at sites of disturbed blood flow by activating inflammatory and proliferative transcriptional programmes in endothelium.
13:00-14:30 Lunch and Poster Session 1
14:30-15:55 Imaging of Blood Vessels Chairs: Kim van der Heiden and Ton van der Steen
14:30-14:50 Antoniadis Charalambos, Oxford University, UK
Non-invasive imaging of perivascular fat to predict events.
14:50-15:10 Rene Botnar, King’s College London, UK
Molecular Imaging of advanced plaques.
15:10-15:25 Habib Samedy, Emory Hospital, Atlanta, USA
High Coronary Shear Stress in Patients With Coronary Artery Disease Predicts Myocardial Infarction
15:25-15:40 Yichen Ding, USA
Integrating Light-Sheet Imaging with Advanced Computation to Recapitulate Developmental Cardiac Mechanics
15:40-15:55 Jason Tarkin, Cambridge, UK
Coronary artery inflammation compared to wall shear stress, plaque composition and peri-coronary adipose tissue using PET-CT
15:55-16:25 Coffee break
16:25-17:20 Gender and Cardiovascular Disease  Chairs: Steve White and Jolanda Wentzel
16:25-16:45 Hester den Ruijter, UMCU, NL
Gender differences in CVD- plaque erosion.
16:45-17:05 T Christian Gasser, KTH Royal Institute of Technology
Gender differences in AAA
17:05-17:20 Francoise Lenfant, Inserm, Toulouse, Fr
Gender differences in blood flow-mediated remodeling
17:20-21:00 Conference Dinner and Drinks -

Friday 12th April 2019

08:00-08:50  Coffee, Thea and Poster Session
08:50-09:00 Opening: Peter Weinberg 
09:00-09:30 Keynote Lecture 2 Chair: Paul Evans
  Michael Simons, Yale, USA
Cell fate and aortic aneurysm
09:30-10:25 Pulse Wave Analysis Chairs: Jordi Alastruey and Frank Gijsen
09:30-09:50 Kim Parker, Imperial College London, UK
Future Directions for Wave Intensity Analysis
09:50-10:10 Peter Weinberg, Imperial College London, UK
A non-invasive method for measurement of arterial wave speed, intensity and refections
10:10-10:25 Sam Vennin, KCL, UK
Ventricular dynamics is a main determinant of the augmentation index: An in in vivo and in silico study
10:25-11:00 Coffee break
11:00-12:25 What is the cause of plaque destabilization? Chairs: Peter Stone and Christina Warboys
11:00-11:20 Patrick Segers, University of Ghent, BE
Wall shear stress and plaque development: did we buy a pig in a poke
11:20-11:40 Martin Bennet, Cambridge University, UK 
Wall stress is the main determinant of plaque rupture
11:40-11:55 Sandro Satta, Manchester, UK
A pivotal role for Nrf2 in endothelial detachment– implications for endothelial erosion of stenotic plaques
11:55-12:10 Christos Bourantas, QMUL/UCL, UK
Prognostic implications of endothelial shear stress distribution estimated in three-dimensional quantitative coronary angiography models: A combined analysis of the PROSPECT and IBIS 4 studies
12:10-12:25 Ali C. Akyildiz, ErasmusMC, The Netherlands
Mechanical Predictors of Atherosclerotic Plaque Rupture Beyond “Where Stress, There is Rupture”
12:25-14:00 Lunch and Poster Session 2
14:00-15:30 Cellular Signaling Chairs: Rob Krams and Maria Fragiadaki
14:00-14:20 Holger GerhardtMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), DU
Creating and breaking symmetry in vascular networks
14:20-14:40  Thomas Webb, Leicester, UK
JCAD, a human coronary artery disease gene, is a novel regulator of endothelial hippo signaling
14:40-15:00 Paul Evans, Sheffield University, UK
Notch signaling in mechanotransduction
15:00-15:15 Nicole van Engeland, Eindhoven, the Netherlands
Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic forces
15:15-15:30 Christina Warboys, Imperial College, UK
Inflammatory Activation of Endothelial Cells Induced by Disturbed Flow is Regulated by Frizzled-4 and β-catenin via a Non-Canonical Pathway
15:30-16:00 Awards, closing and drinks