At the recent British Society for Matrix Biology (BSMB) meeting in Cardiff, Clare Thompson was awarded a prize for the best oral presentation by a young investigator. The theme of the meeting was 'Under pressure: the cell's response' with presentations describing the response of cartilage, tendon and other tissues to mechanical loading. Clare's presentation was entitled: 'Primary cilia disassembly down regulates mechanosensitive hedgehog signalling - a feedback mechanism controlling ADAMTS5 expression in chondrocytes. She is just finishing her PhD thesis investigating chondrocyte primary cilia and hedgehog signalling under the supervision of Prof Martin Knight (SEMS) and Dr Paul Chapple (William Harvey Research Institute).